- Viral gastroenteritis research and epidemiology
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Retinal Development and Disorders
- Cerebrovascular and Carotid Artery Diseases
- Ocular and Laser Science Research
- Acute Ischemic Stroke Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Intraocular Surgery and Lenses
- Animal Virus Infections Studies
- Virus-based gene therapy research
- Retinal Imaging and Analysis
- Corneal surgery and disorders
- Viral Infections and Immunology Research
- Retinal and Optic Conditions
- Respiratory viral infections research
- Connexins and lens biology
- Intracranial Aneurysms: Treatment and Complications
- Optical Imaging and Spectroscopy Techniques
- Aldose Reductase and Taurine
- HIV Research and Treatment
- Ocular Diseases and Behçet’s Syndrome
- Protease and Inhibitor Mechanisms
- Advanced MRI Techniques and Applications
- Ophthalmology and Visual Impairment Studies
Georgetown University Medical Center
2004-2025
Georgetown University
2004-2025
University College London
2015-2024
Georgetown Lombardi Comprehensive Cancer Center
2024
University of Birmingham
2023
Institute of Ophthalmology
1985-2019
AZ Technology (United States)
2019
Virginia Commonwealth University
2019
Victorian Infectious Diseases Reference Laboratory
2009-2018
University of London
1975-2018
Twenty-four patients of comparable age, blood pressure, and degree dementia were classified by an "Ischemic Score" based on clinical features into "multi-infarct" "primary degenerative" dementia. Regional cerebral flow (CBF) was measured the intracarotid xenon 133 method. Both groups showed a decreased proportion rapidly clearing brain tissue (largely gray matter). Cerebral per 100 gm minute normal in primary degenerative group but low multi-infarct group. This suggests is adequate for...
Critically ill patients who require mechanical ventilation are at increased risk for gastrointestinal bleeding from stress ulcers. There conflicting data on the effect of histamine H2-receptor antagonists and cytoprotective agent sucralfate rates bleeding, ventilator-associated pneumonia, mortality.
Journal Article REGIONAL CEREBRAL OXYGEN SUPPLY AND UTILIZATION IN DEMENTIA: A CLINICAL PHYSIOLOGICAL STUDY WITH OXYGEN-15 POSITRON TOMOGRAPHY - 15 TOMOHRAPHY Get access R. S. J. FRACKOWIAK, FRACKOWIAK From the MRC Cyclotron Unit, and Department of Medicine (Neurology), Hammersmith HospitalLondon W12 OHSNational Hospital for Nervous DiseasesQueen Square, London WCIIII Neurological Clinic, University RomeItaly Search other works by this author on: Oxford Academic PubMed Google Scholar C....
Clinical NMR imaging of the brain: 140 casesGM Bydder, RE Steiner, IR Young, AS Hall, DJ Thomas, J Marshall, CA Pallis and NJ LeggAudio Available | Share
Abstract Data on 1898 menstrual cycles, for 241 married women, were analysed by means of a quantal regression programme. The locations the day ovulation was determined basal body temperature method. Estimates obtained risk conception from an act coitus each day, as measured ovulation. relationship between fecundability and coital frequency also examined.
In 4,470 critically ill patients, we examined the impact of transfusion practice on mortality rates. As compared with survivors, patients who died in intensive care units (ICU) had lower hemoglobin values (95 +/- 26 versus 104 23 g/L, p < 0.0001) and were transfused red cells more frequently (42.6% 28.0%, 0.0001). cardiac disease, there was a trend toward an increased when 95 g/L (55% 42%, = 0.09) as anemic other diagnoses. Patients anemia, high APACHE II score (> 20), diagnosis...
The relationships between cerebral blood flow (CBF), arterial oxygen content, whole viscosity and the transport of to brain have been studied in 54 subjects with variations content resulting from alterations haemoglobin concentration ranging 5.7 19.1 g/dl. A highly significant relationship was found CBF altering maintain rate within certain limits. No effect changes evident. In a multiple regression analysis emerged as major determinant after this had taken into account there no influence...
Background Despite practice guidelines promoting delirium assessment in intensive care, few data exist regarding current practices among nurses and how these compare with those for sedation assessment. Objectives To identify perceptions of care to assessing sedation. Methods A paper/Web-based survey was administered 601 staff working 16 units at 5 acute hospitals specifying the Boston, Massachusetts area. Results Overall, 331 (55%) responded. Only 3% ranked as most important condition...
The time of onset a completed stroke was recorded in 707 patients. Of the 554 cerebral infarctions 40% occurred between midnight and 6 a.m. Onset at night was, if anything, less common among 153 cases hemorrhage.
While the use of a protocol to guide sedation and analgesia therapy in intensive care unit has been shown improve patient outcomes, compliance is often poor. We hypothesized that formal, consistent intervention by pharmacists promote adherence our institution's guidelines would clinical outcomes. The purpose this study was document impact daily pharmacist interventions on outcomes patients prescribed continuous sedative therapy.Before-after study.Two medical units (total 18 beds) at...
To determine whether the volume of retinal tissue passing between inner and outer retina in macular edema could be used as an indicator visual acuity.Diabetic uveitic patients with cystoid (81 subjects, 129 eyes) were recruited. Best corrected logMAR acuity spectral optical coherence tomography (OCT/SLO; OTI, Toronto, ONT, Canada) performed all patients. Coronal OCT scans obtained from a cross section plexiform layers analyzed grid five concentric radii (500, 1000, 1500, 2000, 2500 μm...
A series of comparative exposures to both argon and krypton lasers have been made at 3 locations in a human retina--the fovea, the macula, intraretinal vessels. In fovea irradiations resulted damage inner outer retinal layers as result absorption within pigment epithelium macular pigment, while damaged retina choroid. macula systems retina, again sufficient radiation passed into choroid induce blood vessel occlusion, haemorrhage, oedema. When vessels were irradiated, only with was energy...