Shaohui Yang

ORCID: 0000-0001-6543-8175
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About
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Research Areas
  • RNA modifications and cancer
  • Cancer-related gene regulation
  • Cancer-related molecular mechanisms research
  • Studies on Chitinases and Chitosanases
  • MicroRNA in disease regulation
  • Neonatal Health and Biochemistry
  • Head and Neck Cancer Studies
  • Plant Ecology and Soil Science
  • Renal and Vascular Pathologies
  • Galectins and Cancer Biology
  • Drug-Induced Hepatotoxicity and Protection
  • Bone Metabolism and Diseases
  • Ferroptosis and cancer prognosis
  • Epigenetics and DNA Methylation
  • Acupuncture Treatment Research Studies
  • Liver Disease and Transplantation
  • Metabolism and Genetic Disorders
  • Land Use and Ecosystem Services
  • Molecular Biology Techniques and Applications
  • Metabolism, Diabetes, and Cancer
  • Retinal Imaging and Analysis
  • Forest Management and Policy
  • Lung Cancer Treatments and Mutations
  • Chronic Kidney Disease and Diabetes
  • Cholangiocarcinoma and Gallbladder Cancer Studies

Ningxia Water Conservancy
2025

Ningbo Medical Center Lihuili Hospital
2021-2022

Ningbo University
2022

Shantou University
2019

First Affiliated Hospital of Shantou University Medical College
2019

First Affiliated Hospital of Henan University of Science and Technology
2017

China Medical University
1993-1995

Biomass is a vital index used to evaluate the vegetation rebuilding effect of mining slopes after restoration. It essential establish models for estimating biomass and carbon storage community on slopes. Therefore, this paper establishes such vegetation, taking an abandoned quarry ecological restoration in Yixing City, Jiangsu Province, as research object. Firstly, variables estimation were determined based correlation analysis results; model was comprehensively selected, accuracy optimal...

10.3390/su17020734 article EN Sustainability 2025-01-17

Dysregulated microRNAs (miRNAs) are common in human cancer and involved the proliferation, promotion, metastasis of tumor cells. Therefore, this study aimed to evaluate expression biological function miR-1236-3p colon cancer. This screened miRNA normal tissues through array analysis. In addition, quantitative Reverse Transcription-Polymerase Chain Reaction (qRT-PCR) analysis was performed validate from patients cell lines. Online predicting algorithms luciferase reporter assays were also...

10.3389/fonc.2021.688882 article EN cc-by Frontiers in Oncology 2021-09-03

To develop clinical nomograms for prediction of overall survival (OS) and cancer-specific (CSS) in patients with stage IV tongue squamous cell carcinoma (TSCC) after surgery based on the Surveillance, Epidemiology, End Results (SEER) program database.We collected data resected TSCC from SEER database, divided them into training set validation by 7:3 randomly. Kaplan-Meier analysis Cox regression were adopted to distinguish independent risk factors OS CSS. Clinical constructed predict 3-year...

10.1097/md.0000000000016206 article EN cc-by-nc Medicine 2019-06-01

Colon cancer is highly prevalent, and cell proliferation migration are major reasons for its progression to malignancy. The upregulation of INHBA, a glycoprotein hormone that regulates the secretion pituitary hormones, documented be oncogenic in numerous cancers, consisting breast, gastric, ovarian cancer. Herein, we assessed role INHBA along with colon cells.TCGA datasets were used assess expression correlation prognosis patients. Analyses on JASPAR, PROMO, ENCODE databases, uncovered high...

10.1002/jcla.24539 article EN Journal of Clinical Laboratory Analysis 2022-06-11

The present study investigated the expression, mutation, and methylation profile of PNN its prognostic value in digestive tract cancers. disparities signaling pathways immune landscape colon adenocarcinoma (COAD) based on expression were specifically explored.The levels PNN, survival data esophageal cancer, gastric adenocarcinoma, COAD, rectal evaluated using several bioinformatic databases. Gene Ontology (GO) enrichment analysis gene set (GSEA) performed to investigate enriched biological...

10.1002/jcla.24327 article EN cc-by-nc Journal of Clinical Laboratory Analysis 2022-03-08

Insulin resistance promotes the occurrence of liver cancer and decreases its chemosensitivity. Rosiglitazone (ROSI), a thiazolidinedione insulin sensitiser, could be used for diabetes with has been reported to show anticancer effects on human malignant cells. In this paper, we investigated combination ROSI chemotherapeutics growth metastasis insulin-resistant hepatoma. vitro assay, significantly enhanced inhibitory adriamycin (ADR) proliferation, autophagy migration hepatoma HepG2/IR cells...

10.1080/1061186x.2020.1844216 article EN Journal of drug targeting 2020-10-29

Effects of acupuncture on experimental hyperbilirubinemia and cholangitis were studied in male rats (n = 33). The group treated with acupuncture, 18, 12 6 hr prior to 6, 18 after oral administration α-napthylisothiocyanate (ANIT, 100 mg per Kg). Rats sacrificed 48 hours challenge. Serum liver samples taken for biochemical histological analysis, respectively. Results this study revealed that ANIT exhibited elevations bilirubin, SGOT SGPT as well cholangitis. In receiving ANIT, morphological...

10.1142/s0192415x95000171 article EN The American Journal of Chinese Medicine 1995-01-01

The effects of moxibustion on experimental hyperbilirubinemia and cholangitis were studied in male rats (n=33). group treated with moxibustion, 18, 12 6 hours prior to 6, 18 after challenge oral α-napthylisothiocyanate (AN1T, 100 mg per kg). Rats sacrificed 48 challenge. Serum liver samples taken for biochemical histological analysis, respectively. results revealed that ANIT exhibited elevations bilirubin, SGOT SGPT as well cholangitis. In receiving ANIT, morphological parameters injury...

10.1142/s0192415x93000273 article EN The American Journal of Chinese Medicine 1993-01-01

Background: Astragaloside (AS) has been clinically used in the management of fracture, but underlying mechanism AS involved fracture healing is still unknown, so objective our study was to explore above potential AS. Materials and Methods: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay, flow cytometry analysis, real-time polymerase chain reaction, Western blot computational luciferase immunohistochemistry (IHC) were utilized detect healing. Results: Cell growth rate,...

10.4103/pm.pm_656_18 article EN Pharmacognosy Magazine 2020-01-01

Abstract Objective To observe the expression of YKL-40 in serum patients with colorectal cancer and to study effect gene on proliferation angiogenesis colon cell lines. Methods Serum samples 79 before 7 days after surgery, 13 precancerous lesions 21 healthy controls were collected, was detected by enzyme-linked immunosorbent assays (ELISAs). The HCT116 line high selected from lines HCT-15, SW480, then, cells divided into an experimental group a control group. inhibited small interfering RNA...

10.21203/rs.3.rs-1089158/v2 preprint EN Research Square (Research Square) 2022-03-10

Abstract Background: Pinin (PNN) was originally identified for acting an essential role in epithelial cell-cell adhesion. We aim to illuminate the expression profile, mutation feature, methylation status of PNN and its prognostic value digestive tract cancers. Methods: Expression data PNN, as well clinical information on esophagus cancer (ESCA), gastric adenocarcinoma (STAD), colon (COAD) rectal (READ) were acquired from The Cancer Genome Atlas database. expression, feature prognosis...

10.21203/rs.3.rs-705965/v1 preprint EN cc-by Research Square (Research Square) 2021-08-03

Abstract Objective To observe the expression of YKL-40 in serum patients with colorectal cancer, and to study effect gene on proliferation angiogenesis colon cancer cell lines. Methods The precancerous lesions, healthy controls were collected, was detected by enzyme-linked immunosorbent assay (ELISA) technology. Screened lines high from HCT-15, HCT-116, SW480, interfered through siRNA technology, co-cultured bevacizumab, cells CCK8 method Proliferation, formation test detect blood vessel...

10.21203/rs.3.rs-1089158/v1 preprint EN cc-by Research Square (Research Square) 2021-11-30
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