- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Functional Brain Connectivity Studies
- Medical Imaging Techniques and Applications
- MRI in cancer diagnosis
- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Atomic and Subatomic Physics Research
- NMR spectroscopy and applications
- HIV Research and Treatment
- Neural and Behavioral Psychology Studies
- Photoacoustic and Ultrasonic Imaging
- Fetal and Pediatric Neurological Disorders
- Transcranial Magnetic Stimulation Studies
- Parkinson's Disease Mechanisms and Treatments
- Ultrasound Imaging and Elastography
- Visual perception and processing mechanisms
- Genetic Neurodegenerative Diseases
- Retinal Imaging and Analysis
- Prion Diseases and Protein Misfolding
- Electrical and Bioimpedance Tomography
- Advanced X-ray Imaging Techniques
- Spinal Dysraphism and Malformations
- Neurological disorders and treatments
- Bone and Joint Diseases
University of Arizona
2017-2025
Duke University Hospital
2013-2023
Duke Medical Center
2013-2023
Banner - University Medical Center Tucson
2018-2022
Duke University
2011-2021
Durham VA Medical Center
2018
Rogers (United States)
2017
Widener University
2015
National Tsing Hua University
2011
National Sun Yat-sen University
2011
A brain-computer interface (BCI) is a way of conveying an individual's thoughts to control computer or electromechanical hardware. Capitalizing on the ability characterize brain activity in reproducible manner, we explored possibility using real-time fMRI interpret spatial distribution function as BCI commands. Using high-field (3T) MRI scanner, activities associated with four distinct covert functional tasks were detected and subsequently translated into predetermined commands for moving...
Aberrant accumulation of transition metals in the brain may have an early and important role pathogenesis several neurodegenerative disorders, including Huntington disease (HD).To comprehensively evaluate validate distribution metal deposition using advanced magnetic resonance imaging methods from premanifest through symptomatic stages HD.Observational study.University center.Twenty-eight HD expanded gene carriers, 34 patients with HD, 56 age- sex-matched healthy control subjects were...
Meditation practice alters intrinsic resting-state functional connectivity (rsFC) in the default mode network (DMN). However, little is known regarding effects of meditation on other networks. The aim current study was to investigate experience and meditation-state (msFC) multiple networks (RSNs). practitioners (MPs) performed two 5-minute scans, one during rest, while meditating. A naïve control group (CG) underwent scan. Exploratory regression analyses relations between years rsFC msFC...
Abstract A technique suitable for diffusion tensor imaging (DTI) at high field strengths is presented in this work. The method based on a periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) k ‐space trajectory using EPI as the signal readout module, and hence dubbed PROPELLER EPI. implementation of included series correction schemes to reduce possible errors associated intrinsically higher sensitivity off‐resonance effects. Experimental results 3.0 Tesla...
Connectivity mapping based on resting-state fMRI is rapidly developing, and this methodology has great potential for clinical applications. However, before can be applied diagnosis, prognosis, monitoring treatment an individual patient with neurologic or psychiatric diseases, it essential to assess its long-term reproducibility between-subject variations among healthy individuals. The purpose of the study was quantify test-retest ICN measures derived from variation across whole...
Purpose A projection onto convex sets reconstruction of multiplexed sensitivity encoded MRI (POCSMUSE) is developed to reduce motion‐related artifacts, including respiration artifacts in abdominal imaging and aliasing interleaved diffusion‐weighted imaging. Theory Images with reduced are reconstructed an iterative (POCS) procedure that uses the coil profile as a constraint. This method can be applied data obtained different pulse sequences k‐space trajectories. In addition, various...
Background Diffusion imaging holds great potential for the non‐invasive assessment of glymphatic system in humans. One technique, diffusion tensor along perivascular space (DTI‐ALPS), has introduced ALPS‐index, a novel metric evaluating diffusivity within space. However, it still needs to be established whether observed reduction ALPS‐index reflects axonal changes, common occurrence neurodegenerative diseases. Purpose To determine alterations can influence change ALPS‐index. Study Type...
A novel and effective technique is described for distortion correction in echo planar imaging (EPI) utilizing the field maps derived from multi-echo gradient-echo images. The distortions different off-resonance related factors such as inhomogeneity, eddy current effect, radiofrequency pulse frequency offset, chemical shift effect can be simultaneously reduced to a great extent. With proposed post-processing algorithm of multi-channel modulation, may corrected without unwrapping phase...
Quantitative susceptibility mapping (QSM) measures tissue magnetic and typically relies on time-consuming three-dimensional (3D) gradient-echo (GRE) MRI. Recent studies have shown that two-dimensional (2D) multi-slice echo-planar imaging (GRE-EPI), which is commonly used in functional MRI (fMRI) other dynamic techniques, can also be to produce data suitable for QSM with much shorter scan times. However, the production of high-quality maps difficult because obtained by 2D scans often phase...
Abstract Odd–even echo inconsistencies result in Nyquist ghost artifacts the reconstructed EPI images. The reduce image signal‐to‐noise ratio and make it difficult to correctly interpret data. In this article a new 2D phase mapping protocol postprocessing algorithm are presented for an effective removal. After appropriate k ‐space data regrouping, map accurately encoding low‐ high‐order errors is derived from two phase‐encoded reference scans, which were originally proposed by Hu Le (Magn...
We report a functional magnetic resonance imaging method to deliver task-specific brain activities as biofeedback signals guide individuals increase cortical activity in auditory areas during sound stimulation. A total of 11 study participants underwent multiple scan sessions, while the changes activated volume within primary and secondary were fed back them between sessions. On basis feedback information, attempted number significant voxels subsequent trial sessions by adjusting their level...