A5103226588- Fluorine in Organic Chemistry
- Cyclopropane Reaction Mechanisms
- Asymmetric Synthesis and Catalysis
- Chemical Synthesis and Analysis
- Synthesis and Reactions of Organic Compounds
- Synthesis and Catalytic Reactions
- Synthesis of β-Lactam Compounds
- Asymmetric Hydrogenation and Catalysis
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Axial and Atropisomeric Chirality Synthesis
- Catalytic C–H Functionalization Methods
- Inorganic Fluorides and Related Compounds
- Catalytic Cross-Coupling Reactions
- Fuel Cells and Related Materials
- Synthesis and Biological Evaluation
- Molecular spectroscopy and chirality
- Carbohydrate Chemistry and Synthesis
- Porphyrin and Phthalocyanine Chemistry
- Synthetic Organic Chemistry Methods
- Electrocatalysts for Energy Conversion
- Insect and Pesticide Research
- Analytical Chemistry and Chromatography
- Chemical Synthesis and Reactions
- Advanced MRI Techniques and Applications
Setsunan University
2015-2024
Kyoto University
2002-2024
Kobe University
2007-2022
Mitsui Chemicals (Germany)
2021
University of Yamanashi Hospital
2018-2020
Soochow University
2020
Slovak University of Technology in Bratislava
2020
Jiangxi Provincial People's Hospital
2020
University of Minnesota
2020
Institute of Chemical Technology
2020
An analytical in-situ technique was utilized to evaluate reactant gas transport resistance (Rother) in catalyst layers (CLs). It found that Rother increased with the decrease of Pt-loadings CLs although their thickness decreased. Effective Knudsen diffusion coefficient calculated from pore size distribution and porosity. estimated almost steady regardless Pt-loadings. To understand increase Rother, a simple model established including secondary pores local around Pt surface. should be...
The influence of the ionomer content on proton transport phenomena in catalyst layers a fuel cell was examined using pseudo (PCLs) consisting carbon support and ionomer. Effective conductivity PCL increased with increasing both graphitized ketjen black (GKB) (KB) systems. It found that coverage θ Bruggeman factor γ, which is related to tortuosity path PCL, did not depend appreciably. In GKB system, volume fraction dominant difference . However, results water adsorption analysis heterogeneous...
A highly reactive alkylrhodium complex was formed from Me2Zn and RhCl(PPh3)3 effectively catalyzed a Csp3–Csp3 homocoupling reaction of benzyl halides. coupling using Rh catalyst has not been reported up to now. The proceeded under very mild conditions gave the corresponding products even if they had substituents such as an uncovered formyl or hydroxymethyl group.
An understanding of potential age-related changes in brain stiffness and its regional variation is important for further clinical application MR elastography.To investigate the effect age on global young middle-aged adults.Prospective.Fifty subjects with normal brains aged their 20s, 30s, 40s, 50s, or 60s (five men, five women per decade).3.0T MRI elastography a vibration frequency 60 Hz.Stiffness was measured nine regions (cerebrum, temporal lobes, sensorimotor areas, frontotemporal...
Synthesis of α-CF3 carbonyl compounds has been recognized to be difficult up now because the polarization CF3δ−-Iδ+ is opposite that CH3δ+-Iδ−, and this makes it introduce CF3+ unit enolates. We recently reported an effective α-trifluoromethylation ketones by using Et2Zn with Rh catalyst, but mechanism not fully cleared. Now, we carried out detailed mechanistic studies found involvement a highly reactive alkylrhodium complex which derived from RhCl(PPh3)3 in α-trifluoromethylation....
(E)-Trimethyl-(3,3,3-trifluoroprop-1-enyl)silane (1) was synthesized as a reagent for use in Hiyama cross-coupling reactions the production of β-trifluoromethylstyrene derivatives. Cross-coupling 1 with electronically diverse aryl iodides achieved by treatment CsF presence catalytic amounts palladium to afford desired products moderate good yields.
A nickel-catalyzed Negishi coupling of bromodifluoroacetamides with arylzinc reagents has been developed. This reaction allows access to difluoromethylated aromatic compounds containing a variety aryl groups and amide moieties. Furthermore, highly effective transformation the functionalized difluoromethyl group (−CF2CONR1R2) was realized via microwave-assisted reduction under mild conditions. The notable features this strategy are its generality use low-cost nickel catalyst ligand; thus,...
Abstract This account concentrates on our new methodologies for the synthesis of fluorine analogues amino acids and their derivatives using Reformatsky‐type reactions ethyl bromodifluoroacetate dibromofluoroacetate with imines promoted by Wilkinson catalyst. First, we present rhodium‐catalyzed reaction diethylzinc chemoselective α,α‐difluoro‐β‐lactams non‐cyclized products, 3‐alkylamino‐2,2‐difluorocarboxylates. was expanded to asymmetric difluoro‐β‐lactams two types chiral auxiliaries. To...
An enantioselective Reformatsky reaction has been developed for the of ethyl dibromofluoroacetate (1) with an imine. This method represents first ligand-promoted imino-Reformatsky approach to use a halofluoroacetate. The amino alcohol ligand allowed preparation enantioenriched α-bromo-α-fluoro-β-lactams in good yields enantioselectivities up 96% ee. process also provided access β-lactam rings bearing two stereogenic centers.
The atomic-scale mechanism of enhanced ionic conductivity in (Ba,Ca)F 2 with isovalent cation mixing is revealed via a first-principles investigation defect formation and migration.
Treatment of alpha,beta-unsaturated ketones with CF(3)I in the presence Et(2)Zn and RhCl(PPh(3))(3) gave novel alpha-trifluoromethylation products good yields. Hydrogen transfer from ethyl group on rhodium complex to beta-position enone seems play an important role this reaction.
A new fluorous ligand was synthesized from the acetonide of dimethyl tartarate, which showed excellent asymmetric induction on addition dimethylzinc to aldehydes. This will be useful for synthesis bioactive compounds with a methyl carbinol moiety. It could recycled without using solvent or column.
1,3-Diketones were synthesized from α,β-unsaturated ketones by treatment with acid chlorides and Et2Zn in the presence of RhCl(PPh3)3. This is a very simple extremely chemoselective reaction to give adduct at α-position ketones.
Ethyl bromodifluoroacetate reacted with alkenyl or aryl iodides in the presence of copper powder dimethyl sulfoxide (DMSO) to give corresponding alkynyl- aryldiffuoroacetates moderated good yields.
Metabolism of imidacloprid in the housefly Musca domestica was investigated. After injection 14C-labeled imidacloprid, radioactivity decreased to approximately 20% initial level within 24 hr. Most 14C excreta as well that insect body accounted for by an olefin derivative imidacloprid. The pre-application piperonyl butoxide or propargyl propyl phenylphosphonate a synergist suppressed degradation and delayed excretion insecticidal components from houseflies. These results suggested activity...