A5028981615- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Immune Cell Function and Interaction
- Brucella: diagnosis, epidemiology, treatment
- Insect symbiosis and bacterial influences
- Galectins and Cancer Biology
- Reproductive System and Pregnancy
- Immunotherapy and Immune Responses
Universidade Nova de Lisboa
2019-2025
Chagas disease (CD) is a vector-borne Neglected Zoonotic Disease (NZD) caused by flagellate protozoan, Trypanosoma cruzi, that affects various mammalian species across America, including humans and domestic animals. However, due to an increase in population movements new routes of transmission, T. cruzi infection presently considered worldwide health concern, no longer restricted endemic countries. Dogs play major role the cycle acting very efficiently as reservoirs allowing perpetuation...
Leishmaniasis is a group of parasitic diseases whose etiological agent the protozoa Leishmania . These afflict impoverished populations in tropical and subtropical regions affect wild domestic animals. Canine leishmaniasis global disease mostly caused by L. infantum Dogs are recognized as good reservoir since harbor infection long before developing disease, facilitating parasite transmission. Furthermore, there growing evidence that dogs may also be American spp. amazonensis The innate...
Dendritic cells (DCs) capture pathogens and process antigens, playing a crucial role in activating naïve T cells, bridging the gap between innate acquired immunity. However, little is known about DC activation when facing
African trypanosomiasis or sleeping sickness is a zoonotic disease caused by Trypanosoma brucei, protozoan parasite transmitted Glossina spp. (tsetse fly). Parasite introduction into mammal hosts triggers succession of events, involving both innate and adaptive immunity. Macrophages (MΦ) have key role in defence since they are antigen-presenting cells microbicidal function essential for trypanosome clearance. Adaptive immune carried out lymphocytes, especially T that promote an integrated...