Filomena Conforti

ORCID: 0000-0001-6699-005X
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About
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Research Areas
  • Phytochemistry and Biological Activities
  • Essential Oils and Antimicrobial Activity
  • Phytochemicals and Antioxidant Activities
  • Natural Antidiabetic Agents Studies
  • Natural product bioactivities and synthesis
  • Pharmacology and Obesity Treatment
  • Sesquiterpenes and Asteraceae Studies
  • Plant Toxicity and Pharmacological Properties
  • Cholinesterase and Neurodegenerative Diseases
  • Plant chemical constituents analysis
  • Natural Compound Pharmacology Studies
  • Phytochemistry and biological activities of Ficus species
  • Synthesis and biological activity
  • Chemical synthesis and alkaloids
  • Drug-Induced Hepatotoxicity and Protection
  • Bee Products Chemical Analysis
  • Insect Pest Control Strategies
  • Phytochemistry and Bioactive Compounds
  • Computational Drug Discovery Methods
  • Photodynamic Therapy Research Studies
  • Insect and Pesticide Research
  • Medicinal Plants and Neuroprotection
  • Phytochemistry and Bioactivity Studies
  • Bioactive Compounds and Antitumor Agents
  • Cynara cardunculus studies

University of Calabria
2016-2025

Nutrition Sciences (Belgium)
2014

The chemical composition and antioxidant activities of wild cultivated Laurus nobilis leaves Foeniculum vulgare subsp. piperitum seeds were determined. Differences found in the total phenolic content fennel. GC-MS analysis non polar fractions showed a different between plants. Cultivated laurel had high terpenes such as linool, α-terpinol, α-terpinyl acetate, thymol, caryophyllene, aromandrene, selinene, farnesene, cadinene, while eugenol methyl eugenol, vitamin E, sterols. potential...

10.1248/bpb.29.2056 article EN Biological and Pharmaceutical Bulletin 2006-01-01

The pandemic, due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has stimulated the search for antivirals tackle COVID-19 infection. Molecules with known pharmacokinetics and already approved human use have been demonstrated or predicted be suitable used either directly as a base scaffold-based drug design. Among these substances, quercetin is potent in vitro inhibitor of 3CLpro, SARS-CoV-2 main protease. However, its low vivo bioavailability calls modifications molecular...

10.3390/biomedicines9040375 article EN cc-by Biomedicines 2021-04-02

This study reports on the biological properties, antioxidant and antidiabetic, of two varieties Amaranthus caudatus seeds, Oscar blanco Victor red. Oil, squalene phenolic contents were also determined. Seeds both investigated found to possess very different levels (2.2% in variety 7.5% red variety). Although activity A. var. statistically did not differ significantly from each other (IC50 values ethyl acetate extracts 0.50 mg/ml 0.62 mg/ml, respectively), significant differences noticed...

10.1248/bpb.28.1098 article EN Biological and Pharmaceutical Bulletin 2005-01-01

The present study showed for the first time in vitro properties (antioxidant, hypoglycaemic and anticholinesterase) of Citrus medica L. cv. Diamante which belongs to Rutaceae family. n-hexane extract citron peel is characterized by presence monoterpenes sesquiterpenes. most abundant constituents were two monoterpenes: limonene gamma-terpinene. significant antioxidant activity that was carried out using different assays (DPPH test, beta-carotene bleaching test bovine brain peroxidation...

10.1002/ptr.2077 article EN Phytotherapy Research 2007-01-18

This study aimed to investigate the acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activity of essential oils from Pinus nigra subsp. nigra, P. var. calabrica, heldreichii leucodermis. is relevant treatment Alzheimer’s disease (AD), since cholinesterase drugs are currently only available treat AD. leucodermis exhibited most promising activity, with IC50 values 51.1 80.6 μg/mL against AChE BChE, respectively. An interesting was also observed oil, an value 94.4 μg/mL....

10.3109/14756360903389856 article EN Journal of Enzyme Inhibition and Medicinal Chemistry 2010-04-30

Inhibition of digestive enzymes is one the most widely studied mechanisms used to determine potential efficacy natural products as anti-obesity agents. In vitro studies reported here were performed evaluate inhibitory activity formulations edible plants from Italy on amylase and lipase by monitoring hydrolysis nitrophenyl caprilate glycoside bonds in digestible carbohydrate foods.The formulation obtained Capparis sicula exhibited strongest effect pancreatic (IC50 = 0.53 mg mL(-1) ) while...

10.1002/jsfa.6544 article EN Journal of the Science of Food and Agriculture 2013-12-21
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