A5100442331- Endometrial and Cervical Cancer Treatments
- Cervical Cancer and HPV Research
- Uterine Myomas and Treatments
- Ovarian cancer diagnosis and treatment
- Endometriosis Research and Treatment
- Pelvic and Acetabular Injuries
- Pelvic floor disorders treatments
- Colorectal and Anal Carcinomas
- Osteoarthritis Treatment and Mechanisms
- Pregnancy and preeclampsia studies
- Anorectal Disease Treatments and Outcomes
- Cancer Risks and Factors
- Radiomics and Machine Learning in Medical Imaging
- Urological Disorders and Treatments
- MRI in cancer diagnosis
- Hernia repair and management
- Maternal and fetal healthcare
- Venous Thromboembolism Diagnosis and Management
- Gynecological conditions and treatments
- Reproductive System and Pregnancy
- Reproductive Biology and Fertility
- Urinary Bladder and Prostate Research
- Knee injuries and reconstruction techniques
- Vascular Procedures and Complications
- Cancer-related molecular mechanisms research
Southern Medical University
2016-2025
Nanfang Hospital
2016-2025
Peking University
2013-2025
Peking University Third Hospital
2009-2025
Fuyang City People's Hospital
2024-2025
Shanghai Medical Information Center
2024
Development Research Center
2024
University of Calgary
2017-2024
Zhejiang University
2024
Second Affiliated Hospital of Guangzhou Medical University
2024
Background Building on earlier work, the toxicity probability interval (TPI) method, we present a modified TPI (mTPI) design that is calibration-free for phase I trials. Purpose Our goal to improve trial conduct and provide more effective designs while maintaining simplicity of original design. Methods Like mTPI consists practical dose-finding scheme guided by posterior inference simple Bayesian model. However, new method proposes improved decision rules based statistic, unit mass (UPM). For...
The aim of the present study was to validate usefulness new octapolar multifrequency bioelectrical impedance analysis (BIA) for assessment appendicular skeletal muscle mass (ASM) by comparing it with that dual-energy X-ray absorptiometry (DXA) and investigate prevalence sarcopenia in Chinese community-dwelling elderly according Asian Working Group Sarcopenia (AWGS) definition.A cross-sectional conducted communities Chengdu, China. A total 944 adults aged ≥60 years were included. ASM measured...
Bacterial infections in wounds continue to be a major challenge clinical settings worldwide and represent significant threat human health. This work proposes novel expandable versatile methods for solidifying sodium alginate (SA) with metal ions (such as Fe
ABSTRACT The pharmacokinetics of intravenous anidulafungin in adult intensive care unit (ICU) patients were assessed this study and compared with historical data from a general patient population healthy subjects. Intensive plasma sampling was performed over dosing interval at steady state 21 ICU candidemia/invasive candidiasis. All received the recommended regimen (a 200-mg loading dose on day 1, followed by daily 100-mg maintenance dose), except for 54-year-old 240-kg female (who 150-mg...
Abstract BACKGROUND: Mycosis fungoides (MF) and leukemic Sézary syndrome (SS) are the most common cutaneous T cell lymphomas (CTCL), but their etiology remains unknown. After patients were observed with hydrochlorothiazide (HCTZ)‐associated CTCL, HCTZ was examined as a putative chronic antigen in cohort of prospectively staged patients. METHODS: Demographic drug exposure data from 1443 confirmed MF SS Hypertensive CTCL divided into users or nonusers for statistical analysis by chi‐square t...
In the presence of Ru(phen)3Cl2 or fac-Ir(ppy)3 under visible-light irradiation, addition fluorinated radicals to N-arylacrylamides followed by an intramolecular cyano group insertion cascade cyclization process produced trifluoroalkyl difluoroalkyl phenanthridine derivatives in moderate good yields. Three easily available fluoroalkylated reagents CF3SO2Cl, BrCF2CO2Et and BrCF2PO(OEt)2 were used as sources radicals.
Does protein source or human serum albumin (HSA) in embryo culture media influence the subsequent birthweight? A significant difference was observed gestational age- and gender-adjusted birthweight (Z scores) proportion of large-for-gestational age (LGA) babies between embryos cultured G1 v5 those G1-PLUS media. It has been reported that birthweights singletons born from Vitrolife are significantly higher than Cook group media, (Vitrolife, Gothenburg, Sweden) is associated with increased...
Purpose: The actual incidence of deep vein thrombosis (DVT) in femoral neck fractures is underestimated. This study aimed to investigate the DVT lower extremities after fracture before and operation. Methods: clinical data patients with treated at Xi’an Honghui Hospital between July 1, 2016, December 31, 2018, were collected. examined ultrasonography operation divided into non-thrombosis groups according their ultrasonographic results. was reported as a percentage. Results: rates...
Urticaria is a common skin disease characterized by episodes of wheals, and it has negative effect on patients' quality life. Large-scale population-based epidemiological studies urticaria are scarce in China. The aim this survey was to determine the prevalence, clinical forms, risk factors Chinese population.This conducted 35 cities from 31 provinces, autonomous regions, municipalities Two three communities each city were selected investigation. Participants completed questionnaires...
Abstract Purpose To develop and validate a deep learning‐based pathological risk score (RS) with an aim of predicting patients' prognosis to investigate the potential association between information within whole slide image (WSI) cervical cancer prognosis. Methods A total 251 patients International Federation Gynecology Obstetrics (FIGO) Stage IA1–IIA2 who underwent surgery without any preoperative treatment were enrolled in this study. Both clinical characteristics WSI each patient...
Radical hysterectomy combined with pelvic lymphadenectomy is the standard treatment for early-stage cervical cancer, but unrecognized nerves are vulnerable to irreversible damage during surgery. This early clinical trial investigated feasibility and safety of intraoperative near-infrared (NIR) fluorescence imaging (NIR-FI) indocyanine green (ICG) identifying radical cancer.Sixty-six adults cancer were enrolled in this prospective, open-label, single-arm, single-center trial. NIR-FI was...
Objective: To investigate whether pretreatment CT-derived radiomic features could be applied for prediction of clinical response to neoadjuvant chemotherapy (NACT) in locally advanced cervical cancer (LACC). Patients and Methods: 277 LACC patients treated with NACT followed by surgery/radiotherapy were included this multi-institution retrospective study. 1294 extracted from venous contrast enhanced non-enhanced CT imaging each patient. Five combined methods feature selection used reduce...
Abstract Objective To compare survival outcomes of different postoperative adjuvant therapies (PATs) for early‐stage cervical cancer (ECC) patients with one intermediate‐risk pathological factor (IPF). Methods A total 2889 stage IA1 to IIA2 were included in this study. Three PAT groups identified, namely a no therapy (NAT) group ( n = 773), an radiotherapy/chemoradiotherapy (ART) 1648) and chemotherapy (ACT) 468). Kaplan–Meier analysis COX regression used the overall (OS) disease‐free (DFS)...
To compare the long-term survival outcomes, recurrence patterns and morbidity of type B C radical hysterectomy (RH) for stage IB2 cervical cancer (FIGO 2018). Based on FOUR-C database, patients who underwent or RH in 47 hospitals from 2004 to 2018 were reviewed. Univariate multivariate analyses performed 5-year overall (OS) recurrence-free (RFS), between two groups after propensity score matching (PSM). A total 1308 enrolled this study, 840 468 C. There was no difference outcomes C, either...