Fatima Benchikh

ORCID: 0000-0001-6863-8818
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Research Areas
  • Phytochemicals and Antioxidant Activities
  • Phytochemistry and Biological Activities
  • Medicinal Plant Research
  • Natural Antidiabetic Agents Studies
  • Essential Oils and Antimicrobial Activity
  • Phytochemical and Pharmacological Studies
  • Ethnobotanical and Medicinal Plants Studies
  • Cholinesterase and Neurodegenerative Diseases
  • Flavonoids in Medical Research
  • Complementary and Alternative Medicine Studies
  • Medicinal Plants and Neuroprotection
  • Drug-Induced Hepatotoxicity and Protection
  • Herbal Medicine Research Studies
  • Nigella sativa pharmacological applications
  • Natural Products and Applications
  • Natural Compound Pharmacology Studies
  • Insect and Pesticide Research
  • Diet and metabolism studies
  • Natural product bioactivities and synthesis
  • Insect Pest Control Strategies
  • Gastrointestinal motility and disorders
  • Food Science and Nutritional Studies
  • melanin and skin pigmentation
  • Pharmacology and Nanomedicine Research
  • Traditional Chinese Medicine Analysis

University Ferhat Abbas of Setif
2015-2025

The phytochemical study of Galium tunetanum Lam., Rubiaceae, leaves led to the isolation 13 compounds from chloroform–methanol and methanol extracts, including six iridoid glycosides, one non-glycoside iridoid, two p-coumaroyl phenolic acids, flavonoid glycosides. structural determination isolated was performed by mono- bidimensional NMR spectroscopic data, as well ESI-MS experiments. All were this species for first time. anti-angiogenic effects iridoids also reported on new blood vessels...

10.1016/j.bjp.2018.03.010 article EN cc-by-nc-nd Revista Brasileira de Farmacognosia 2018-05-01

In this study, Salvia aegyptiaca and verbenaca aerial part decoction methanol extracts (SAE DE, SAE ME, SVR ME) were screened for their in vitro antioxidant, anti-Alzheimer, antidiabetic enzymes inhibition activities. The antioxidant properties of determined using DPPH radical scavenging, ABTS Alkaline DMSO superoxide β-carotene bleaching, reducing power, metal chelating activity assays. All showed high capacity the with best performance detected ME ME. S. a low inhibitory...

10.1111/jfbc.13472 article EN Journal of Food Biochemistry 2020-09-30

Background/aim: This study explores the antiulcer activity of different doses Salvia aegyptiaca (SAE) methanol (ME) and decoctedextracts (DE) on ethanol-induced gastric ulcers in rats.Materials methods: Female Wistar rats weighing 180–200 g were divided into five groups: control, omeprazole (positive control),and extract-treated (100, 200, 400 mg/kg). Ulcers induced with absolute ethanol 30 min after treatment extracts.The experiment was followed by macroscopic histopathological examination....

10.55730/1300-0152.2722 article EN TURKISH JOURNAL OF BIOLOGY 2025-02-24

The objective of this effort is to quantify the amounts phenolics and in vitro antioxidant capacities Allium sphaerocephalon L. flowers’ hydroethanolic (EOH) aqueous (AQE) extracts. two extracts' total phenolic (TPC) flavonoid content (TFC) were determined spectrophotometrically. Results showed extraction yield obtained by EOH AQE 18.30% 11.80%, respectively. gave higher TPC (12.73±0.91µg GAE/mg DW) TFC (7.67±0.24µg QE/mg than (TPC = 9.71±0.53µg DW TFC= 5.68±0.90µg QE/ mg DW). Five...

10.52711/0974-360x.2024.00140 article EN Research Journal of Pharmacy and Technology 2024-02-20

Phytotherapy has known a great evolution all the world and some medicinal plants are important remedies of diseases. Ammoides atlantica is one used in folk medicine. This study aims to estimate total phenolics flavonoids contents then investigate both vitro antioxidant activity models aqueous extract (AqE) from atlantica. Total polyphenol were determined using Folin Ciocalteu's reagent; quantified employing AlCl3 Method. The property was assessed by DPPH-scavenging radicals lipid...

10.22270/jddt.v10i3-s.4151 article EN Journal of Drug Delivery and Therapeutics 2020-06-30

Oxidative stress resulted from free radicals and reactive oxygen species (ROS) are associated with many diseases. Phytotherapy has known a great evolution all the world some medicinal plants important remedies of Myrtle (Mrytus communis L.) is plant Myrtaceae family which common in Mediterranean region, flowering, always green leaves fruit. This study aims to investigate vitro antioxidant capacity Myrtus berries methanol extract its three fractions using five assays: ABTS scavenging...

10.24925/turjaf.v10i6.1089-1094.5062 article EN cc-by-nc Turkish Journal of Agriculture - Food Science and Technology 2022-07-03

Artemisia absinthium L. is a medicinal plant largely used in traditional medicine. The aim of this study was to estimate the content polyphenols, and flavonoids compounds also evaluate antioxidant anti-ulcer activities Aqueous extract from aerial parts. Folin-Ciocalteau AlCl3 methods were applied order quantify polyphenolic contents, respectively. However, DPPH method vitro activity. Quantitative analysis yield phenolic aqueous showed that 19.32% its 58.66 ± 2.16 μg GAE / mg dry for...

10.22270/jddt.v10i4.4253 article EN Journal of Drug Delivery and Therapeutics 2020-07-15

Reactive oxygen (ROS) and nitrogen species (RNS) are produced in all cells play important roles physiology. The loss of the redox balance, either by an increase oxidant molecules ROS RNS or decreased antioxidant system activities cause a state oxidative stress. Several studies going on worldwide directed towards finding natural antioxidants plant origin. Plants containing phenolic compounds have been reported to possess strong activity. objective this study is evaluate total polyphenols...

10.22270/jddt.v10i4-s.4245 article EN Journal of Drug Delivery and Therapeutics 2020-08-15

The objective of this study is to evaluate the antioxidant, antiulcer, anti-inflammatory and analgesic activity aqueous extract Angelica archangelica L., a medicinal plant traditional pharmacopoeia Algeria. showed large amount total polyphenols, tannins, chlorophyll a, b, carotenoids small flavonoids with values 80.16±14.3 mg EAG/g extract, 3.12±2.01 EQ/g 226.10±4.50 EAT/g 6.10±50.62, 12.00±31.53 1.78±0.40 μg/mL respectively. In addition, A. high ability trap DPPH radical in IC50 at...

10.24925/turjaf.v10i2.334-340.5023 article EN cc-by-nc Turkish Journal of Agriculture - Food Science and Technology 2022-03-03

Ocimum basilicum L. (O. L.) with the vernacular name of Reihan or Reyhan is a medicinal plant from Lamiaceae family, widely used in traditional Algerian medicine. The aim present study was to research uses and mode application O. M’sila region (northern Algeria), estimate content polyphenols flavonoids methanolic aqueous extracts this evaluate antioxidant activity these by 2, 2’-diphenyl-1-picryl hydrazyl (DPPH). results ethnopharmacological survey showed that decoction leaves fresh dry form...

10.22270/jddt.v10i4-s.4308 article EN Journal of Drug Delivery and Therapeutics 2020-08-15

This study aimed to estimate the total phenolic and flavonoid contents evaluate antioxidant activity of Hydro-methanolic from Saccocalyx satureioides Coss Dur aerial part. Total polyphenols were determined using Folin-Ciocalteu’s reagent. The flavonoids estimated method Aluminum chloride (AlCl3). capacity was evaluated two in vitro models (the 1,1-diphenyl-2-picrylhydrazyl (DPPH) reducing power). content extract 171.34 ±1.43 mg Gallic acid equivalent/g dry (GAE/g) 18.6 ± 0.46 Quercetin...

10.22270/jddt.v10i4.4166 article EN Journal of Drug Delivery and Therapeutics 2020-07-15

Free radicals or highly reactive oxygen species are capable of inducing oxidative damage to the human body Plants containing phenolic compounds have potent antioxidant capacity. The present study was undertaken investigate in vitro activities Myrtus communis L. (Myrtaceae), a plant widely used as natural remedy for digestive disorders folk medicine. Total polyphenol contents were determined using Folin Ciocalteu's reagent; flavonoids quantified employing AlCl3 Method. EAE extract showed...

10.24925/turjaf.v10i4.760-765.5060 article EN cc-by-nc Turkish Journal of Agriculture - Food Science and Technology 2022-05-06

Phlomis crinita is a plant species of the family Lamiaceae including more than 100 perennial herbs, shrubs, and sub-shrubs native to Mediterranean, Central Asia, India. This commonly good natural source various secondary metabolites. Therefore, present study was conducted determine phenolic content antioxidant activity hydromethanolic (PC ME) aqueous extracts AQE) aerial parts P. crinita. Total polyphenols, flavonoids tannins were quantified, respectively by methods Folin-Ciocalteu reagent,...

10.24925/turjaf.v10i10.2061-2066.5173 article EN cc-by-nc Turkish Journal of Agriculture - Food Science and Technology 2022-11-08

Foeniculum vulgare Mill, known as fennel, is a medicinal plant of the Apiaceae family, widely used in traditional Algerian medicine. The aim this study was to estimate polyphenols and flavonoids content evaluate antioxidant, analgesic antiulcer activities aqueous extract F. seeds. Quantitative determination total revealed that contained 551.45±0.010 mg gallic acid equivalent/g dry 284.83±0.008 quercetin respectively. gastroprotective effect showed able protect stomach against lesions induced...

10.24925/turjaf.v10i10.2010-2015.5185 article EN cc-by-nc Turkish Journal of Agriculture - Food Science and Technology 2022-11-02

Thymelaea hirsuta (L.) Endl. , known as ‘Methnane’ in Algeria, is a widely medicinal plant used folk medicine. In the present study, vitro antioxidant activity of T. hirsta extracts and impact extraction solvent polarity on potential were investigated. Three types polar solvents with decreasing chosen; water for decocted extract, methanol-water at 50% absolute methanol macerated extracts. Total phenolic flavonoid contents evaluated showed high amount wihch decreases increasing polarity....

10.24925/turjaf.v11i6.1161-1167.5931 article EN cc-by-nc Turkish Journal of Agriculture - Food Science and Technology 2023-06-30

The Achillea genus is often used in traditional medicine for the treatment of digestive disorders. current research sought to understand mechanisms action decocted extract Achillea odorata L., with a focus on its possible effects neurotransmitters that control gastrointestinal motility, as well how it affected intestinal transit (IT) and gastric emptying (GE). Mice were given ADE treatments at 100, 200, or 400 mg.kg-1 doses, an hour later they phenol red meal. To determine effect...

10.26538/tjnpr/v8i1.6 article EN cc-by-nc-nd Tropical Journal of Natural Product Research 2024-02-01

This study investigated the influence of Salvia barrelieri (SBA) methanol and decocted extracts (ME DE) on intestinal transit (IT) gastric emptying (GE) in mice. Only doses ME SBA induced a strong inhibition GE at 46.82 ± 4.34, 54.71 3.29 48.45 1.33% (P≤0.0001) for dosages 100, 200 or 400 mg·kg-1 respectively. The by themselves had no effects movement (only slight, non–significant increase mg·kg-1). However, blocking muscarinic receptors resulted decrease IT 10.34 17.53% with DE extracts,...

10.52973/rcfcv-e34410 article EN cc-by-nc-sa Revista Científica de la Facultad de Ciencias Veterinarias 2024-07-08

Purpose: To determine the polyphenol content of methanol extract (ME) Lavandula stoechas L. aerial part and its anti-diarrheal antisecretory activities in mice. Method: Methanol was used to plant's powder. Spectrophotometric techniques were employed extract's total phenol, flavonoid tannin content. The effect on secretion diarrhea at three concentrations (50, 250 500 mg/kg) evaluated by castor oil method. administered rats orally loperamide a dose 5 mg/kg served as reference drug. Acute...

10.4314/tjpr.v23i3.3 article EN cc-by Tropical Journal of Pharmaceutical Research 2024-04-14

Background: Matricaria chamomilla L. (M. chamomilla) is a famous medicinal plant distributed worldwide. It widely used in traditional medicine to treat all kinds of diseases, including infections, neuropsychiatric, respiratory, gastrointestinal, and liver disorders. also as sedative, antispasmodic, antiseptic, antiemetic. Our aims this study was thus quantify the phenolic, flavonoids contents flower plant, evaluate vitro antioxidant potential vivo analgesic activity. Methods: The total...

10.24925/turjaf.v10i10.2076-2080.5330 article EN cc-by-nc Turkish Journal of Agriculture - Food Science and Technology 2022-11-09

The plants of the genus Phlomis are native to Turkey, North Africa, Europe and Asia. bovei De Noé (Lamiaceae) is a rare Algerian endemic plant, commonly known as Kayat El Adjarah. objective this study quantify polyphenol content evaluate antioxidant activities ethanolic extract (EthE) Noé. plant was prepared by macerating 100 g ground material in 1000 ml 85 % ethanol for 72 h, then filtrate evaporated using rotary evaporator at temperature 45C dried. total polyphenols determined Folin...

10.22270/jddt.v10i5.4339 article EN Journal of Drug Delivery and Therapeutics 2020-09-15

The genus Achillea (Yarrow)is one of the most important medicinal plants. Nowadays, different functions yarrow such as spasmolytic, choleretic, treatment wounds and anti-inflammatory activities, make it an plant. purpose this study was to determine antioxidant activity aqueous (AAE) methanol (AME) extracts from plant santolinoides L. (A. L.) aerial parts in vitro. Quantitative evaluation polyphenols, flavonoids tannins were determined using Folin-Ciocalteu reagent, aluminum chloride (AlCl3)...

10.24925/turjaf.v10i10.2045-2050.5249 article EN cc-by-nc Turkish Journal of Agriculture - Food Science and Technology 2022-11-08
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