A5034075445- Colorectal Cancer Screening and Detection
- Gastroesophageal reflux and treatments
- Gastric Cancer Management and Outcomes
- Eosinophilic Esophagitis
- Cancer Immunotherapy and Biomarkers
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Colorectal Cancer Treatments and Studies
- Colorectal Cancer Surgical Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Systemic Sclerosis and Related Diseases
- Melanoma and MAPK Pathways
- Helicobacter pylori-related gastroenterology studies
- Polyomavirus and related diseases
- Dysphagia Assessment and Management
- Liver Disease Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Long-Term Effects of COVID-19
- Genetic factors in colorectal cancer
- HER2/EGFR in Cancer Research
- Lung Cancer Treatments and Mutations
- Monoclonal and Polyclonal Antibodies Research
- Cancer, Lipids, and Metabolism
- Esophageal Cancer Research and Treatment
- Drug-Induced Hepatotoxicity and Protection
UConn Health
2020-2023
University of Connecticut
2020-2022
Albany Medical Center Hospital
2021-2022
Loyola University Medical Center
2022
Edward Hines, Jr. VA Hospital
2022
Loyola University Chicago
2022
New York State Department of Health
2021
Beth Israel Deaconess Medical Center
2013-2014
Harvard University
2013-2014
V-RAF murine sarcoma viral oncogene homolog B1 (BRAF) mutated non-small-cell lung cancer (NSCLC) is an exceptionally rare form of cancer, found only in one to two percent patients with NSCLC diagnosis. BRAF traditionally affects former or active smokers. mutations have always been special interest the oncological community, as they offer potential for targeted therapies. mutation spectrum includes that are both V600 and non-V600 types. activating mutation, which results high kinase activity...
Ineffective esophageal motility (IEM) is one of the most common disorders. However, definition IEM has evolved. Chicago classification version 4.0 (CCv4.0) made parameters more stringent with greater than 70% ineffective wet swallows (WS) necessary to diagnose conclusive IEM. Of swallows, 50-70% are deemed "inconclusive cases". This study sought determine whether provocative maneuvers, including multiple rapid (MRS) and apple viscous (AVS), impedance clearance can provide supportive...
Coronavirus disease (COVID-19) pandemic has rapidly spread around the world. As new complications associated with virus become more apparent, concerns in medical community continue to grow. One of commonly encountered and troubling critically ill patients been hypercoagulable state subsequent thrombotic events. Within spectrum observed events, pulmonary embolism seems prevail. These trends are concerning reinforce current recommendations on anticoagulation virus. To illustrate variety...
The serrated pathway accounts for 30%-35% of colorectal cancer (CRC).Unlike hyperplastic polyps, both sessile lesions (SSLs) and traditional adenomas are premalignant lesions, yet SSLs considered to be the principal precursor CRCs.Serrated represent a challenge in detection, classification, removal-contributing post-colonoscopy cancer.Therefore, it is utmost importance characterize these properly ensure complete removal.A retrospective cohort study developed diagnostic scoring system...
Introduction Lung cancer is the leading cause of cancer-related deaths with non-small cell lung (NSCLC) being most common them. About a third NSCLC cases have an epidermal growth factor (EGFR) mutation, which usually susceptible to tyrosine kinase inhibitors (TKIs). In rare where patients progress through TKI therapy, use immune checkpoint (ICIs) remains controversial. Case report We describe case patient significant history smoking and EGFR mutated programmed death ligand-1 (PD-L1) positive...
Among the patients who present to emergency room or a primary care office with symptoms of dysphagia, chest pain, and reflux, approximately 9% have an underlying rheumatological condition. It is not surprising that many internal medicine clinicians frequently overlook this etiology investigate other causes first. However, overwhelming number conditions (61.1%) some form esophageal dysmotility ranges from ineffective motility (IEM) achalasia. We case systemic lupus erythematosus (SLE) absent...
Introduction: There is a known association between treatment with tumor necrosis factor alpha (TNF-α) inhibitors and melanoma [1]. Despite some reported adverse effects including increased risk of melanoma, TNF-α antagonists have become one the mainstay therapies in management ulcerative colitis (UC) We are going to present UC patient who developed ocular while treated inhibitor bring more attention this rare complication encourage routine screening for patients on antagonist. Case...
Esophageal cancer grows fastest in the US as screening is quite challenging. Endoscopic polarized scanning spectroscopic imaging combined with diffuse reflectance spectroscopy can significantly improve chances of esophageal pre-cancer detection.
We present a combined approach for isolating fetal nucleated red blood cells from the maternal supply purpose of genetic screening. The final step, spectroscopic microscopy, identifies with native contrast.
Background and objectivesMany liver society guidelines no longer recommend single value alpha-fetoprotein (AFP) for hepatocellular carcinoma (HCC) screening because of poor specificity sensitivity. Instead, use longitudinal AFP expression changes is recommended. However, specific guidance has been provided as to what levels change should be regarded suspicious. The aim this study was determine whether an slope cut-off exists that could useful early diagnosis HCC.