- Cardiac Imaging and Diagnostics
- Genetic Associations and Epidemiology
- Cardiovascular Health and Disease Prevention
- Cerebrovascular and Carotid Artery Diseases
- Nerve injury and regeneration
- Pluripotent Stem Cells Research
- Pancreatic function and diabetes
- Neurogenesis and neuroplasticity mechanisms
- Bioinformatics and Genomic Networks
- Bipolar Disorder and Treatment
- Diabetes Management and Research
- Diabetes and associated disorders
National Institutes of Health
2020
National Institutes of Health Clinical Center
2017
Thomas Jefferson University
2015
To determine the relationship between American College of Cardiology/American Heart Association (ACC/AHA) risk score and plaque phenotype coronary carotid arteries assessed directly using CT angiography MRI.Asymptomatic subjects eligible for statin therapy by were enrolled in a prospective study disease burden artery calcium (CAC) scoring, angiography, MRI arteries. Quartiles calculated noncalcified plaque, CAC, average wall volume compared with ACC/AHA quartiles.Two hundred three studied...
Background: Type 1 diabetes (T1D) cannot be explained by environmental factors alone and gene mutations in T1D should also taken seriously. The aim of this study was to investigate the novel genetic risk systematically reviewing published literature performing a meta-analysis.Methods: A comprehensive search electronic databases completed using Illumina BioEngine. Seven case/control bio-sets from four different studies were selected, including 286 cases 162 controls. selected top genes...
Background: Bipolar disorder (BP) is one of the most common mental illnesses, with underlying mechanisms remaining unclear. The aim this study to investigate novel genetic risk BP by systematically reviewing published literature and performing a meta-analysis. Method: A comprehensive search electronic databases was completed using Illumina BioEngine. RNA expression data from brain tissue 198 cases 160 controls were analyzed, including six case/control bio-sets four recent studies. selected...