A5108708463- Galectins and Cancer Biology
- Glycosylation and Glycoproteins Research
- Lung Cancer Treatments and Mutations
- Neural Networks and Applications
- Lung Cancer Diagnosis and Treatment
- Advanced Breast Cancer Therapies
- RNA modifications and cancer
- Advanced DC-DC Converters
- Mathematics, Computing, and Information Processing
- Human Pose and Action Recognition
- Visual Attention and Saliency Detection
- Vitamin D Research Studies
- Ferroelectric and Negative Capacitance Devices
- Drilling and Well Engineering
- Medical and Biological Ozone Research
- Ferroptosis and cancer prognosis
- Power System Reliability and Maintenance
- Phonocardiography and Auscultation Techniques
- Spaceflight effects on biology
- Power Systems Fault Detection
- Smart Grid and Power Systems
- Power Transformer Diagnostics and Insulation
- Anesthesia and Sedative Agents
- Respiratory viral infections research
- Surgical Simulation and Training
Capital Medical University
2024-2025
George Washington University
2025
Gilead Sciences (United States)
2024-2025
Huawei Technologies (China)
2025
Chongqing Maternal and Child Health Hospital
2025
Wannan Medical College
2024
Beijing University of Agriculture
2024
China Mobile (China)
2024
State Grid Corporation of China (China)
2024
University of Jinan
2024
Primary liver cancer has consistently exhibited a high prevalence and fatality rate, necessitating the investigation of associated diagnostic markers inhibition mechanisms to effectively mitigate its impact. The significance apolipoprotein M (ApoM) in impeding progression neoplastic ailments is progressively gaining recognition. However, comprehensive understanding underlying mechanism advancement remains be elucidated. Recent evidence indicates potential association between ApoM...
BackgroundSeveral respiratory infections outbreaks have been observed in mainland China after reduction of non-pharmaceutical interventions. Other countries seen increases outside typical seasons post-COVID-19, warranting investigation into underlying causes.MethodsWe established monitoring networks for suspected infection 14 tertiary hospitals nationwide. PCR SARS-CoV-2, influenza A and B were performed on 3708 specimens deep sequencing conducted to identify co-infections or newly emerging...
The grouting repair process of the sealing baffle on surface dam cracks can improve slurry diffusion distance in cracks; however, must be optimized. To address problem crack technology underwater concrete with one section open and other closed, a analysis model was established. By adjusting various parameters process, influences pressure, position hole, diameter water pressure Bingham fluid these were studied. results show that hole significantly influence limited cement cracks. With an...
Synchronous multiple primary lung cancer (sMPLC) exhibits distinct histopathological characteristics among pulmonary nodules. However, a comprehensive understanding of the somatic mutation landscape and transcriptome heterogeneity is lacking. Therefore, our study aims to meticulously investigate genomic distinctions nodules within individual patients. We performed targeted DNA sequencing on tumor specimens conducted bulk RNA analysis 53 originating from 26 The same patient was determined as...
Abstract Cyclin-dependent kinases 4 and 6 (CDK4/6) are crucial in regulating cell cycle progression cancer development. Targeting CDK4/6 has shown considerable promise treating various cancers, including breast cancer. Despite significant therapeutic efficacy, resistance to inhibitors (CDK4/6i), such as palbociclib, remains a substantial hurdle clinical practice. Using co-culture system, cytokine array, quantitative high-throughput combinatorial screening (qHTCS), we discovered mechanism by...
<div>Abstract<p>Cyclin-dependent kinases 4 and 6 (CDK4/6) are crucial in regulating cell-cycle progression cancer development. Targeting CDK4/6 has shown considerable promise treating various cancers, including breast cancer. Despite significant therapeutic efficacy, resistance to inhibitors (CDK4/6i), such as palbociclib, remains a substantial hurdle clinical practice. Using coculture system, cytokine array, quantitative high-throughput combinatorial screening, we discovered...
<p>Supplementary Figures</p>
e17624 Background: Trophoblast cell surface antigen 2 (Trop-2), encoded by the transmembrane calcium signal transducer gene, TACSTD2 , is highly expressed in many cancers, including endometrial cancer (EC). Sacituzumab govitecan (SG), a Trop-2-directed antibody-drug conjugate coupled to SN-38 (a topoisomerase 1 [Top1] inhibitor), being evaluated EC. Data describing expression EC are limited. We used Tempus AI, Inc., real-world data understand and TOP1 gene its association with other...
<title>Abstract</title> Background: Administering anesthesia for circumcision in children involves prioritizing safety, comfort, and quality of recovery. While the effectiveness remimazolam besylate pediatric requires additional confirmation, sevoflurane has been linked to complications like agitation delirium upon This research intends evaluate anesthetic impacts, recovery features, safety profiles compared between ages 3 12 undergoing circumcision. Additionally, it seeks investigate...
The mental health inequality between migrants and non-migrants was exacerbated by the COVID-19 pandemic. Identifying key determinants of this is essential in promoting equity.
1075 Background: In the phase 3 TROPiCS-02 study, SG, a Trop-2–directed antibody-drug conjugate coupled to SN-38 as payload, demonstrated clinically meaningful improvement in survival outcomes over chemotherapy patients (pts) with pretreated HR+/HER2- mBC. leads double-stranded DNA damage, therefore we hypothesized that tumors defective DDR machinery, SG may provoke synthetic lethality. We report on comprehensive genomic analysis of gene variants and impact clinical efficacy this patient...
Aiming at the advantages of interventional surgical robot system in flexibility, safety and accuracy, a compact continuous delivery catheter drive mechanism for is designed its structure optimized analyzed. Firstly, analysis axial feed part circumferential rotation carried out to ensure flexibility accuracy mechanism. Secondly, solution problem difficult disinfection proposed, improved by improving structure. In addition, clamping has been enhance stability handling performance Finally,...
Graphene, when electrified, generates far-infrared radiation within the wavelength range of 4 μm to 14 μm. This closely aligns with band (3 15 μm), which produces unique physiological effects. Contraction and relaxation vascular smooth muscle play a significant role in primary hypertension, involving nitric oxide-soluble guanylate cyclase–cyclic guanosine monophosphate pathway renin–angiotensin–aldosterone system. study utilized spontaneously hypertensive rats (SHRs) as an untr-HT...
To analyse disorders and components of attention in patients with complicated mild traumatic brain injury. This information is needed to enable clinical workers evaluate provide training for deficits injury.Randomized controlled trial.In-patient community recruitment.In-patients injury (n = 44) community-recruited healthy subjects 45).All participants used a battery tests including the Digit Span Test (DST), Cancellation (D-CAT1 D-CAT2), Symbol Modalities (SDMT), Paced Auditory Serial...
There are many equipment in the substation, and relying on manual inspection often cannot achieve good results. At present, there 3D video sensors installed substations, but due to deployment, problems with low coverage unclear control range. This article establishes a sensor network optimization model based Unity3D, conducts modeling simulation for substations. Utilizing characteristics of Unity3D visualization programmability, coupled device field view is established parameters actual...
To generate data from trained diffusion models, most inference algorithms, such as DDPM, DDIM, and other variants, rely on discretizing the reverse SDEs or their equivalent ODEs. In this paper, we view approaches decomposing entire denoising process into several segments, each corresponding to a transition kernel (RTK) sampling subproblem. Specifically, DDPM uses Gaussian approximation for RTK, resulting in low per-subproblem complexity but requiring large number of segments (i.e.,...