Melinda Mariotti

ORCID: 0000-0001-6901-0168
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About
Contact & Profiles
Research Areas
  • Essential Oils and Antimicrobial Activity
  • Antibiotics Pharmacokinetics and Efficacy
  • Antifungal resistance and susceptibility
  • Infections and bacterial resistance
  • Plant Pathogens and Fungal Diseases
  • Nail Diseases and Treatments
  • Cytomegalovirus and herpesvirus research
  • Polydiacetylene-based materials and applications
  • Complementary and Alternative Medicine Studies
  • Conservation Techniques and Studies
  • Synthesis and Biological Evaluation
  • Mycobacterium research and diagnosis
  • Fungal Biology and Applications
  • Sulfur-Based Synthesis Techniques
  • Advanced Drug Delivery Systems
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Cancer therapeutics and mechanisms
  • Neonatal Respiratory Health Research
  • COVID-19 Clinical Research Studies
  • Antimicrobial Peptides and Activities
  • Neonatal and Maternal Infections
  • Immunotherapy and Immune Responses
  • Diphtheria, Corynebacterium, and Tetanus
  • Piperaceae Chemical and Biological Studies
  • Neonatal Health and Biochemistry

Università Cattolica del Sacro Cuore
2021-2025

Candida auris is a multidrug-resistant fungus known to be global public health problem. The skin-based transmission, together with the marked resistance drugs, resulted in its rapid spread all continents. aim of this study was identify an essential oil (EO) active fight against C. auris. A total 15 EOs were tested 10 clinical strains Cinnamomum zeylanicum EO (CZ-EO) most effective (MIC90 and MFC90 equal 0.06% vol/vol). Three fractions obtained from CZ-EO, cinnamaldehyde (CIN), major chemical...

10.1128/spectrum.04385-22 article EN cc-by Microbiology Spectrum 2023-03-28

The increasing resistance of fungi to antibiotics is a severe challenge in public health, and newly effective drugs are required. Promising potential medications lipopeptides, linear antimicrobial peptides (AMPs) conjugated lipid tail, usually at the N-terminus. In this paper, we investigated vitro vivo antifungal activity three short myristoylated non-myristoylated derived from mutant AMP Chionodracine. We determined their interaction with anionic zwitterionic membrane-mimicking vesicles...

10.3390/ijms23042164 article EN International Journal of Molecular Sciences 2022-02-16

Background/Objectives: In recent years, antimicrobial resistance has become a major threat to global health, and scientific research aiming identify new therapeutic resources is priority. Essential oils (EOs), obtained from spices belonging the culinary tradition, like Carum carvi essential oil (CC-EO), are of great interest for their activity, but methods used evaluate efficacy need be standardized. The aims this work were following: (i) best microbiological in vitro test; (ii) surfactant;...

10.3390/ph18030321 article EN cc-by Pharmaceuticals 2025-02-25

A modern painting is characterized by multi-material bases extremely exposed to biodeteriogenic attacks. The aim of this work was test the antifungal effectiveness a natural, eco-friendly, and safe emulsion based on Citrus aurantium L. var. amara hydrolate Cinnamomum zeylanicum Blume (from bark) essential oil, named "Zeylantium green emulsion" (Zege), paintings. Colored unaged aged canvas samples, performed with techniques (acrylic, vinylic alkyd), were used in vitro both Zege its impact...

10.3390/microorganisms10020205 article EN cc-by Microorganisms 2022-01-19

Functionalized nanoparticles (NPs) represent a cutting edge in innovative clinical approaches, allowing for the delivery of selected compounds with higher specificity wider time frame. They also hold promise novel theranostic applications that integrate both diagnostic and therapeutic functions. Pathogens are continuously evolving to try escape strategies designed treat them.

10.3390/pharmaceutics16091218 article EN cc-by Pharmaceutics 2024-09-18

Onychomycosis (OM) accounts for about 50% of nail disorders in industrialised countries. Essential oils (EOs), aromatic natural compounds, are known their antimicrobial activity.

10.1111/myc.13499 article EN Mycoses 2022-07-17

A 24-year-old male Bangladeshi asylum seeker presented to the emergency department of Policlinico A. Gemelli Rome, Italy with multiple nodular, pruritic lesions on both lower limbs and elbows. We present a skin disease typical for persons living in crowded conditions.

10.1093/jtm/taad073 article EN Journal of Travel Medicine 2023-05-24
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