Melissa Azul

ORCID: 0000-0001-6982-0400
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About
Contact & Profiles
Research Areas
  • Hemoglobinopathies and Related Disorders
  • Iron Metabolism and Disorders
  • Erythrocyte Function and Pathophysiology
  • Blood groups and transfusion
  • Adolescent and Pediatric Healthcare
  • Pharmacological Effects and Toxicity Studies
  • Parvovirus B19 Infection Studies
  • Dermatological and COVID-19 studies
  • Venous Thromboembolism Diagnosis and Management
  • Poverty, Education, and Child Welfare
  • Ultrasound in Clinical Applications
  • Childhood Cancer Survivors' Quality of Life
  • Cannabis and Cannabinoid Research
  • Bone and Joint Diseases
  • Central Venous Catheters and Hemodialysis
  • Resilience and Mental Health
  • Virus-based gene therapy research
  • Homelessness and Social Issues
  • Acute Lymphoblastic Leukemia research
  • CRISPR and Genetic Engineering
  • CAR-T cell therapy research
  • Myeloproliferative Neoplasms: Diagnosis and Treatment

Medical College of Wisconsin
2024-2025

RELX Group (Netherlands)
2022

Michigan United
2022

Temple College
2022

St. Jude Children's Research Hospital
2021-2022

Mayo Clinic
2022

Twin Cities Orthopedics
2021

Mayo Clinic in Florida
2021

University of Minnesota
2020-2021

Mayo Clinic in Arizona
2020-2021

Background/Objectives: Resiliency is critical in coping with stressors associated chronic health diseases. Sickle cell disease (SCD) a blood disorder which familial psychosocial functioning impacts outcomes. We hypothesized that caregiver perceived stress and resiliency are related to the of children SCD may influence clinical Methods: Child-caregiver dyads completed Perceived Stress Scale (PSS-10), Connor Davidson-Resilience (CD-RISC), used 1-5 Likert scale rate frequency they experience,...

10.3390/children12040394 article EN cc-by Children 2025-03-21

Human parvovirus B19 causes life-threatening anemia due to transient red cell aplasia (TRCA) in individuals with sickle disease (SCD). Children SCD experiencing profound during TRCA often require blood transfusions and hospitalization. The prevalence of vitamin deficiencies is high are associated respiratory pain symptoms, but the effects vitamins on acute infection remain unclear. We performed a clinical study which 20 patients hospitalized infections (Day 0) were monitored over 120-day...

10.3390/nu14163415 article EN Nutrients 2022-08-19

Summary Individuals with sickle cell disease (SCD) have historically been considered underweight. Despite increasing body mass index (BMI) in the general population, prevalence of overweight and obese status remains unclear adult SCD population. Our primary aim was to determine identify associations between BMI, demographic, clinical characteristics. We conducted an analysis abstracted electronic health record data patient‐reported outcomes from Sickle Cell Disease Implementation Consortium...

10.1111/bjh.18548 article EN British Journal of Haematology 2022-11-16

Sickle cell disease (SCD) is characterized by sickle hemoglobin (HbS) which polymerizes under deoxygenated conditions to form a stiff, sickled erythrocyte. The dehydration of erythrocytes increases intracellular HbS concentration and the propensity erythrocyte sickling. Prevention this mechanism may provide target for potential SCD therapy investigation. Ionophores such as monensin can increase sodium permeability facilitating its transmembrane transport, leading osmotic swelling decreased...

10.3324/haematol.2021.278666 article EN cc-by-nc Haematologica 2021-10-28
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