A5100387419- Liver Disease Diagnosis and Treatment
- Systemic Lupus Erythematosus Research
- Inflammatory Myopathies and Dermatomyositis
- COVID-19 Clinical Research Studies
- Eosinophilic Disorders and Syndromes
- Systemic Sclerosis and Related Diseases
- Hepatocellular Carcinoma Treatment and Prognosis
- Hepatitis B Virus Studies
- Ocular Diseases and Behçet’s Syndrome
- Alcohol Consumption and Health Effects
- Liver Disease and Transplantation
- Monoclonal and Polyclonal Antibodies Research
- Hepatitis C virus research
- SARS-CoV-2 and COVID-19 Research
- Thyroid Cancer Diagnosis and Treatment
- Immunodeficiency and Autoimmune Disorders
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Autoimmune and Inflammatory Disorders Research
- Rheumatoid Arthritis Research and Therapies
- Air Quality and Health Impacts
- Diet, Metabolism, and Disease
- Muscle Physiology and Disorders
- Long-Term Effects of COVID-19
- Pituitary Gland Disorders and Treatments
Shanghai Jiao Tong University
2022-2025
Shanghai Children's Medical Center
2022-2025
China Agricultural University
2025
Xinjiang Agricultural University
2025
University of Washington
2024
Second Xiangya Hospital of Central South University
2024
Central South University
2022-2024
Xiangya Hospital Central South University
2022-2024
West China Second University Hospital of Sichuan University
2023-2024
Blackboard (United States)
2024
Abstract Background COVID-19 is a viral respiratory disease caused by the severe acute syndrome-Coronavirus type 2 (SARS-CoV-2). Patients with this may be more prone to venous or arterial thrombosis because of activation many factors involved in it, including inflammation, platelet and endothelial dysfunction. Interferon gamma inducible protein-10 (IP-10), monocyte chemoattractant protein-1 (MCP-1) macrophage inflammatory protein 1-alpha (MIP1α) are cytokines related thrombosis. Therefore,...
The aim of this study is to investigate the risk factors for cervical lymph node metastasis in papillary thyroid carcinoma (PTC).The clinicopathological data from 966 PTC patients who underwent operation between January 2013 and December 2015 general surgery department Shengjing Hospital China Medical University were collected. predicting analyzed.Male, age ≤ 45 years old, tumor size> 1.0 cm, extrathyroidal extension (ETE), US features as microcalcification, independent central (CLNM) (P <...
The overall survival of patients with pancreatic cancer is extremely low. Despite multiple large-scale studies, identification predictors patient remains challenging. This study aimed to investigate the prognostic factors for cancer.The clinical data 625 treated at Shengjing Hospital China Medical University from January 2013 December 2017 were collected.Of patients, 569 followed 1 75 months. median was 9.3 1-, 3-, and 5-year rates 37.8%, 15.1%, 10.5%, respectively. Cox proportional hazards...
Abstract Background We and others have confirmed activation of macrophages plays a critical role in liver injury fibrogenesis during HBV infection. And we also proved HBeAg can obviously induce the production macrophage inflammatory cytokines compared with HBsAg HBcAg. However, receptor functional domain its effects mechanisms on hepatic fibrosis remain elusive. Methods The potentially direct binding receptors were screened verified by Co-IP assay. Meanwhile, function accessible peptides for...
Anti-melanoma differentiation-associated protein 5 (MDA5) antibody have been found in dermatomyositis (DM)-associated interstitial lung disease (DM-ILD) and DM-associated rapidly progressive ILD (DM-RPILD). Due to the conflicting results regarding association between anti-MDA5 DM-ILD or DM-RPILD diagnostic value of this for DM-RPILD, we performed meta-analysis. A systematic search was identify studies published January 14, 2017. Sixteen publications with 491 DM versus 605 without ILD, as...
Feeding is essential for animal survival and reproduction regulated by both internal states external stimuli. However, little known about how influence the perception of sensory cues that regulate feeding behavior. Here, we investigated neuronal molecular mechanisms behind nutritional state-mediated regulation gustatory in control behavior brown planthopper Drosophila. We found increases expression cholecystokinin-like peptide, sulfakinin (SK), activity a set SK-expressing neurons....
This study aimed to establish and compare the radiomics machine learning (ML) models based on non-contrast enhanced computed tomography (NECT) clinical features for predicting simplified risk categorization of thymic epithelial tumors (TETs).A total 509 patients with pathologically confirmed TETs from January 2009 May 2018 were retrospectively enrolled, consisting 238 low-risk thymoma (LRT), 232 high-risk (HRT), 39 carcinoma (TC), divided into training (n = 433) testing cohorts 76) according...
Surface-active organics lower the aerosol surface tension (σ
Increasing evidence suggests that the mononuclear/macrophage system is vital in amplifying inflammatory cascade IgA Nephropathy (IgAN). However, pathogenic mechanism of macrophages IgAN and targeted treatment strategies still need to be explored. This study found botanical triterpene celastrol (CLT) effectively alleviated renal lesions, M1-like macrophage infiltration, factors production, improved function mice. We patients had high expression ECM1, a crucial molecule involved polarization,...
Baculoviruses can induce climbing behavior in caterpillar hosts, which provides an excellent model for studying parasite manipulation of host behavior. Herein, we found that Helicoverpa armigera single nucleopolyhedrovirus (HearNPV) promoted lipid metabolism infected H. larvae, and changes affect Therefore, understanding the molecular mechanisms between is particularly important. In this study, adipokinetic hormone 1 (HaAKH1), 2 (HaAKH2) their receptor HaAKHR were essential promoting...
Background: Prunus armeniaca, divaricata, tianshanica, and domestica are valuable ancient tree species that have persisted since the end of Tertiary period within Tianshan wild fruit forest. However, evolutionary relationships among in forest long posed a challenge. Methods: We sequenced assembled chloroplast genomes P. incorporated genome data for comparative analysis to elucidate their phylogenetic positions genus Prunus. Results: The lengths these ranged from 157,395 bp 158,090 bp, with...
Surface-active organics lower the aerosol surface tension (&#963;s/a), leading to enhanced cloud condensation nuclei (CCN) activity and potentially exerting impacts on climate. Quantification of &#963;s/a is mainly limited laboratory or modeling work for particles with selected sizes known chemical compositions. Inferred values from ambient populations are deficient. In this study, we propose a new method derive by combining field measurements made at an urban site in northern China...