- Cellular and Composite Structures
- Advanced Photocatalysis Techniques
- Nanoplatforms for cancer theranostics
- Photonic Crystals and Applications
- Acoustic Wave Phenomena Research
- Marine Biology and Environmental Chemistry
- Automotive and Human Injury Biomechanics
- Luminescence Properties of Advanced Materials
- Elasticity and Material Modeling
- Advanced Nanomaterials in Catalysis
- Minerals Flotation and Separation Techniques
- Land Use and Ecosystem Services
- Glass properties and applications
- Fluid Dynamics Simulations and Interactions
- TiO2 Photocatalysis and Solar Cells
- Coagulation and Flocculation Studies
- Cancer Research and Treatments
- Photodynamic Therapy Research Studies
- Surfactants and Colloidal Systems
- Advanced Materials and Mechanics
- Conservation, Biodiversity, and Resource Management
- Liquid Crystal Research Advancements
- Sulfur Compounds in Biology
- Brake Systems and Friction Analysis
- Electrochemical sensors and biosensors
Hainan University
2024-2025
Southwest Jiaotong University
2023-2025
Shanghai Changzheng Hospital
2025
Southeast University
2024
Guangdong Polytechnic Normal University
2022-2024
Hubei Normal University
2024
Shenzhen University
2024
Shenzhen Second People's Hospital
2024
Management and Science University
2023
Wuhan University of Technology
2023
Fluorophores with donor-acceptor-donor groups the emission spanning second near-infrared window (NIR-II) have recently received great attention for biomedical application. Yet, mechanism underlying equilibrium between fluorescence (radiative decay) and photothermal effect (non-radiative of these fluorophores remains elusive. Here, we demonstrate that a lipophilic NIR-II fluorophore, BPBBT, possesses both twisted intramolecular charge transfer (TICT) aggregation-induced (AIE) characteristics....
Abstract Background Cardiovascular diseases (CVD) represent a major global health challenge, necessitating up-to-date data on its burden for effective care planning and resource allocation. This study comprehensively analyzes the global, regional, national CVD associated risks from 1990 to 2021. Methods Results We performed secondary analysis of risk factors using Global Burden Disease (GBD) 2021 study. In 2021, there were 612 million cases globally, accounting 26.8% all deaths. From...
A novel approach to modulating the chemical state of dopants by engineering topological features a glass matrix is presented. The method allows selective stabilization on wide range length scales, from dispersed ions aggregated clusters nanoparticles, leading various intriguing optical phenomena, such as great emission enhancement and ultra-broadband amplification.
Cancer photodynamic therapy (PDT) represents an attractive local treatment in combination with immunotherapy. Successful cancer PDT relies on image guidance to ensure the accuracy. However, existing nanotechnology for co-delivery of photosensitizers and contrast agents slows clearance from body causes a disparity between release profiles imaging agents. We have found that photosensitizer Chlorin e6 (Ce6) is inherently bound immunoglobulin G (IgG) nanomolarity range affinity. Ce6 IgG...
A novel 3D metamaterial with tension-torsion coupling effect is designed through connecting neighbor chiral honeycomb layers by inclined rods. Both numerical simulation and experiment analysis show the of much better compared to other metamaterials we can find in literatures. With increase cells number, this at strain 1% increases firstly, reaching perk value 11.36°, then decreases slowly, it remains an appreciable 4.44° even when number 25 × 25. Analysis shows that size thickness direction...
Spexin1 (SPX1) is a newly discovered neuropeptide in vertebrates. Its biological function remains to be elucidated. In this study, we have generated the zebrafish spx1 -/- mutant lines using transcription activator-like effector nucleases. Phenotypes of were analyzed order understand effects on reproduction and food intake. The reproductive capability not impaired zebrafish. However, found that fish had higher intake than wild type (WT) fish. Real-time PCR revealed expression level...
Emerging contaminants have recently evolved into a severe worldwide environmental issue. Organophosphate flame retardants (OPFRs) with neurotoxicity, genotoxicity, and reproductive developmental toxicity are class of notorious emerging that cause great concern. The development high-efficiency portable sensors for rapid online monitoring OPFRs has become the primary demand exploration migration transformation OPFRs. In this work, interestingly, cataluminescence (CTL) phenomenon is first...
An innovative three-dimensional (3D) auxetic structure based on 2D re-entrant honeycombs was developed in this article. A sample of the proposed made acrylonitrile–butadiene–styrene (ABS) fabricated through 3D printing technology, and a compression test performed it. Meanwhile, unit cell required for finite-element (FE) analysis determined to simulate behavior structure. Both experimental numerical results showed that can achieve negative Poisson's ratio (NPR) two principal orthogonal...
Abstract Adoptive cell therapy (ACT) has achieved landmark advances in treating cancer clinic. Recent ACT of macrophages engineered to express chimeric antigen receptors (CARs) have shown effectiveness solid tumors. However, the CAR‐macrophage is dependent on tumor recognition and gene editing methods. Herein, an adoptive macrophage presented through copper sulfide nanoparticle‐regulation that exhibits substantial antitumor effect melanoma‐bearing mice, without need for repertoire. Bone...
Abstract Bacteria are utilized as adjuvants for anticancer immunotherapy. However, immunotherapy with bacteria or their extracts is limited due to toxicity. On the basis of innate molecular interactions foreign molecules from bacterial components host pattern recognition receptors (PRRs), a synthetic adjuvant vector morphologically mimicking bacterium engineered, which comprises an optimal combination derived cell wall, flagellum, and nucleoid. The bacterium‐mimicking vectors (BMVs)...
Metallic gold (Au) nanoparticles have great potential for a wide variety of biomedical applications. Yet, slow clearance Au significantly hinders their clinical translation. Herein, we describe strategy utilizing the endogenous copper (Cu) to improve elimination nanoparticles. Our mechanistic study reveals that Cu-transporting P-type ATPase, ATP7B, mediates exocytosis CuS into bile canaliculi rapid hepatobiliary excretion. The efflux is adopted facilitate through CuS–Au conjugation. Using...
Introduction Land resources play a vital role in national economic and social development. Hainan Province faces the challenge of balancing land use with conservation while striving to develop high-quality free trade port. This study aims analyze changes their driving factors support sustainable policies. Methods utilised GlobeLand30 dataset, along data on temperature, precipitation, digital elevation model (DEM), slope, soil, gross domestic product (GDP), population, apply Patch-generating...
Mangroves grow in high-salinity environments with low soil water potential (Ψs), where high light intensity and strong winds increase the vapor pressure deficit (VPD), causing physiological drought transpiration demand (Δw), which limits carbon dioxide (carbon gain) for photosynthesis. This study explored how mangroves optimize their carbon-gain-to-water-loss ratio (water-use strategies) to maximize gain during both dry rainy seasons. We also calculated relative costs of key leaf traits...