A5043698454- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
- Inflammatory Myopathies and Dermatomyositis
- Salivary Gland Tumors Diagnosis and Treatment
- Renal Diseases and Glomerulopathies
- Spondyloarthritis Studies and Treatments
- Health disparities and outcomes
- Salivary Gland Disorders and Functions
- Musculoskeletal synovial abnormalities and treatments
- Advanced Neuroimaging Techniques and Applications
- Inflammatory Bowel Disease
- Lymphoma Diagnosis and Treatment
- Autoimmune and Inflammatory Disorders Research
- Chronic Lymphocytic Leukemia Research
- Dermatological and COVID-19 studies
- Psoriasis: Treatment and Pathogenesis
- COVID-19 Clinical Research Studies
- Cerebral Venous Sinus Thrombosis
- Immunodeficiency and Autoimmune Disorders
- Liver Diseases and Immunity
- Eosinophilic Disorders and Syndromes
- Vasculitis and related conditions
- Systemic Sclerosis and Related Diseases
- Cardiovascular Health and Risk Factors
- Parkinson's Disease and Spinal Disorders
Peking University First Hospital
2016-2025
Peking University
2016-2025
State Ethnic Affairs Commission
2020-2024
Inner Mongolia University for Nationalities
2024
Chongqing Medical University
2019-2022
The Affiliated Yongchuan Hospital of Chongqing Medical University
2019-2022
University of Exeter
2022
<h3>BACKGROUND:</h3> Noninvasive ventilation (NIV) is increasingly used during ventilatory support. Neurally-adjusted assist (NAVA) a mode of mechanical that can improve patient-ventilator interaction. We conducted meta-analysis to compare interaction and clinical outcomes between NAVA pressure support (PSV) in adult subjects NIV. <h3>METHODS:</h3> The PubMed, Cochrane Library, Web Science, OpenGrey, Embase databases were searched for appropriate trials comparing NIV-NAVA with NIV-PSV...
Objective To unravel the dynamical trajectory and features of glucocorticoids (GC) tapering discontinuation in patients with rheumatoid arthritis (RA) commencing GC concomitant conventional synthetic disease-modifying antirheumatic drugs (csDMARDs). Methods We used data from longitudinal real-world Treat-to-TARget RA cohort. Patients who started contaminant csDMARDs therapy were included. The changes dose disease activity evaluated. rate was analysed using Kaplan-Meier analysis. relapse...
To investigate the frequency and determinants of flare in Chinese patients with lupus, focusing on effect glucocorticoid (GC) tapering who achieved low disease activity or remission.We collected baseline follow-up data from all consecutive a prospective lupus cohort between January 2017 December 2020. We defined using status (LLDAS), applied DORIS (Definitions Remission SLE) for remission criteria then assessed SELENA-SLEDAI Flare Index.Among total 185 enrolled, 139 exhibited median 29.8...
Abstract Objective To investigate the frequency and determinants of achieving lupus low disease activity state (LLDAS), effect LLDAS attainment on flare damage accrual in a prospective, single-center cohort Chinese patients. Methods Baseline follow-up data from consecutive patients at Peking University First Hospital were collected January 2017 to June 2020. Results A total 185 enrolled, with median (range) duration enrolment 2.3 (0.8–7.7) years, 2.2 (1.0–2.9) years. By end study, 139...
To evaluate MRI changes to define muscle-lesion specific patterns in patients with antisynthetase syndrome (ASS), and compare them those other common idiopathic inflammatory myopathy subtypes.Qualitative semi-quantitative thigh evaluations were conducted ASS, DM immune-mediated necrotizing (IMNM).This study included 51 56 61 IMNM. Thigh revealed muscle oedema (62.7%), myofascial (90.2%), subcutaneous-tissue (60.8%) fatty infiltration of muscles (68.6%) ASS. Compared IMNM, ASS associated more...
To evaluate the ability of 2017 European League Against Rheumatism/American College Rheumatology (EULAR/ACR) classification criteria for adult and juvenile idiopathic inflammatory myopathies (IIM) to classify IIM in comparison with 1975 Bohan Peter Chinese patients.Two hundred twenty-one inpatients suspected (including 40 children) were retrospectively included this study. The performance EULAR/ACR was evaluated by sensitivity, specificity, positive predictive value, negative value rate,...
The impact of coronavirus disease 2019 (COVID-19) on vulnerable populations with autoimmune inflammatory rheumatic diseases (AIIRDs) has been variable variants and great concern. Here we report the clinical features, outcomes, risk factors for infection hospitalization in patients AIIRDs first wave China December 2022. A real-world survey was conducted Chinese from 8 2022 to 13 January 2023. distributed via internet nationwide, clinic consultation, inpatients at a tertiary hospital Beijing....
Quantitatively staging TAO using MRI remains limited. Our study aims to identify the cut-off signal intensity value for STIR sequence scan.Between June 2018 and July 2020, a number of 51 patients with (102 eyes) 19 volunteer controls (38 were recruited. The clinical biochemical parameters measured in each patient. Disease activity was diagnosed based on Clinical Activity Score (CAS). intensities extraocular muscles scanned short-tau inversion recovery (STIR) sequences from MRI.Compared...
To investigate the prevalence and predictors of sustained remission (SR) in an unselected Chinese rheumatoid arthritis (RA) population.Medical records RA patients from 2009 to 2016 were retrospectively reviewed. Clinical was defined according Disease Activity Score 28 joints using erythrocyte sedimentation rate (DAS28-ESR), Index (CDAI), Simplified (SDAI), Boolean criteria. Remission persisting for at least 6 months regarded as SR (6-month SR). Kaplan-Meier method Cox regression analyses...
Background Mandibular defects pose significant challenges in reconstructive surgery, and scaffold materials are increasingly recognized for their potential to address these challenges. Among various materials, Beta-tricalcium phosphate (β-TCP) is noted its exceptional osteogenic properties. However, improvements biodegradation rate mechanical strength essential optimal performance. Methods In this study, we developed a novel β-TCP-based scaffold, CFBB, by calcining fetal bovine cancellous...
Both mycophenolate mofetil (MMF) and intravenous cyclophosphamide (CYC) have been recommended in the induction therapy of lupus nephritis (LN) for years; nevertheless, their effectiveness safety a real-world setting are extremely lacking. Therefore, we decided to conduct this study.A total 195 Chinese patients with LN who were initially treated MMF (n = 98), or CYC 97) as enrolled. All followed up 12 months. Complete renal remission (CRR) was defined 24-h urinary protein (24 h-UTP) < 0.5 g,...
Abstract Background Diffusion-weighted imaging (DWI) is an essential technique for optic nerve diseases. However, the image quality of DWI decreased by distortions and artifacts associated with conventional techniques. In order to establish this method as a critical tool in diseases, reproducibility feasibility new technical approaches need be systematically investigated. Methods DWIs were acquired using ss-EPI, readout-segmented EPI (rs-EPI) DWI, reduced field-of-view (rFOV) DWI. 26...
To investigate 25S rDNA genotype distribution of vaginal Candida albicans and its relationship with antifungal susceptibility.A total 954 isolates were subjected to analysis according the presence size transposable group Ⅰ intron in PCR; 156 enrolled detect their susceptibility 5 agents M27-A3 broth microdilution method.Totally 876 determined be intronless A(91.8%, 876/954); 58(6.1%, 58/954)and 20 isolates(2.1%, 20/954)were introncontaining B C, respectively. The minimal inhibitory...
Summary RNA testing using RT-PCR can provide direct evidence for diagnoses of COVID-19 which has brought unexpected disasters and changes to our human society. However, the absorption cotton swab lysates may lead a low concentration detectable RNA, might be one main reasons unstable positive detecting rate. We designed manufactured kind silicone with concave-convex structure, further compared effects on extraction. Principal component analysis Paired Wilcoxcon test suggested that higher...
"Successful treatment of rituximab in a steroid-dependent immunoglobulin A vasculitis patient with gastrointestinal involvement: case report." Scandinavian Journal Rheumatology, 52(3), pp. 324–325