Angelica Miglioli

ORCID: 0000-0001-7228-889X
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About
Contact & Profiles
Research Areas
  • Marine Bivalve and Aquaculture Studies
  • Marine Biology and Environmental Chemistry
  • Ocean Acidification Effects and Responses
  • Marine Biology and Ecology Research
  • Environmental Toxicology and Ecotoxicology
  • Aquatic Invertebrate Ecology and Behavior
  • Microplastics and Plastic Pollution
  • Marine Ecology and Invasive Species
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Effects and risks of endocrine disrupting chemicals
  • Calcium Carbonate Crystallization and Inhibition
  • Lipid metabolism and biosynthesis
  • Toxic Organic Pollutants Impact
  • biodegradable polymer synthesis and properties
  • Nanoparticles: synthesis and applications
  • Cephalopods and Marine Biology
  • Fatty Acid Research and Health
  • Pharmacological Effects and Assays
  • Reproductive biology and impacts on aquatic species
  • Metabolomics and Mass Spectrometry Studies
  • Estrogen and related hormone effects
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Laboratoire de Biologie du Développement de Villefranche-sur-Mer
2019-2025

Institut de la Mer de Villefranche
2021-2025

Centre National de la Recherche Scientifique
2018-2024

Sorbonne Université
2018-2024

University of Genoa
2018-2022

Laboratoire de Biologie du Développement
2021

Laboratoire d’Océanographie de Villefranche
2018

Coastal marine ecosystems experience dynamic fluctuations in seawater carbonate chemistry. The importance of this variation the context ocean acidification requires knowing what aspect variability biological processes respond to. We conducted four experiments (ranging from 3 to 22 days) with different regimes (pH T 7.4–8.1) assessing impact diel chemistry on early development mussel Mytilus galloprovincialis . Larval shell growth was consistently correlated mean exposures, regardless...

10.1098/rspb.2018.2381 article EN cc-by Proceedings of the Royal Society B Biological Sciences 2018-12-19

ABSTRACT A model organism in developmental biology is defined by its experimental amenability and resources created for the system scientific community. For most powerful invertebrate models, combination of both has already yielded a thorough understanding processes. However, number systems still limited, their phylogenetic distribution heavily biased. Members one largest animal lineages, Spiralia, example, have long been neglected. In order to remedy this shortcoming, we produced detailed...

10.1242/dev.202256 article EN publisher-specific-oa Development 2024-01-25

Endocrine-disrupting chemicals (EDCs) represent a global threat to human health and the environment. In vertebrates, lipophilic EDCs primarily act by mimicking endogenous hormones, thus interfering with transcriptional activity of nuclear receptors (NRs). The demonstration direct translation these mechanisms into perturbation NR-mediated physiological functions in invertebrates, however, has rarely proven successful, as modes action vertebrates invertebrates seem be distinct. present work,...

10.1098/rstb.2022.0500 article EN Philosophical Transactions of the Royal Society B Biological Sciences 2024-02-05

Bivalve biomineralization is a highly complex and organized process, involving several molecular components identified in adults larval stages. However, information still scarce on the ontogeny of organic matrix before calcification occurs. In this work, first shell formation was investigated mussel Mytilus galloprovincialis. The time course CaCO3 deposition were followed at close times post fertilization (24, 26, 29, 32, 48 h) by calcofluor calcein staining, respectively. Both showed an...

10.1098/rspb.2019.2043 article EN Proceedings of the Royal Society B Biological Sciences 2019-11-27

In the absence of standard methods for detection/quantification nanoplastics (NPs) in environmental samples, commercial nanopolymers are utilized as proxies toxicity testing and risk assessment. marine species, a considerable amount data now available on effects nanopolystyrene (PS-NPs) different size/surface characteristics. this work, amino modified PS-NPs (PS-NH

10.3390/nano11123291 article EN cc-by Nanomaterials 2021-12-04

The broadly utilized biocide triclosan (TCS) is continuously discharged in water compartments worldwide, where it detected at concentrations of ng-µg/L. Given its lipophilicity and bioaccumulation, TCS considered potentially harmful to human environmental health also as a potential endocrine disruptor (ED) different species. In aquatic organisms, can induce variety effects: however, little information available on possible impact invertebrate development. Early larval stages the marine...

10.1007/s11356-023-29854-2 article EN cc-by Environmental Science and Pollution Research 2023-09-20

Predicting the potential for species adaption to climate change is challenged by need identify physiological mechanisms that underpin vulnerability. Here, we investigated sensitivity ocean acidification in marine mussels during early development, and specifically trochophore stage. Using RNA DNA sequencing situ hybridization, identified developmental processes associated with abnormal development rapid adaptation low pH. Trochophores exposed pH seawater exhibited 43 differentially expressed...

10.1016/j.isci.2022.104677 article EN cc-by-nc-nd iScience 2022-06-27

Abstract A model organism in developmental biology is defined by its experimental amenability as well resources created for the system scientific community. For most powerful models, combination of both has already yielded a thorough understanding development. However, number systems still very limited, and their phylogenetic distribution heavily biased. Members one largest animal phyla, mollusks, example, have long been neglected organisms. To remedy this shortcoming, we produced detailed...

10.1101/2023.07.27.550798 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2023-07-28

Abstract One challenge in global change biology is to identify the mechanisms underpinning physiological sensitivities environmental and predict their potential adapt future conditions. Using ocean acidification as representative stressor, molecular pathways associated with abnormal larval development of a globally distributed marine mussel are identified. The targeted developmental stage was trochophore stage, which is, for few hours, pH sensitive main driver success. RNA sequencing situ...

10.1101/2021.10.23.465493 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-10-24

One challenge in global change biology is to identify the mechanisms underpinning physiological sensitivities environmental and predict their potential adapt future conditions. Using ocean acidification as representative stressor, molecular pathways associated with abnormal larval development of a globally distributed marine mussel are identified. The targeted developmental stage was trochophore stage, which is, for few hours, pH sensitive main driver success. RNA sequencing situ...

10.2139/ssrn.3960268 article EN SSRN Electronic Journal 2021-01-01
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