- Genomics and Rare Diseases
- Immunodeficiency and Autoimmune Disorders
- Genomic variations and chromosomal abnormalities
- RNA modifications and cancer
- Cancer-related gene regulation
- Bioinformatics and Genomic Networks
- Kruppel-like factors research
- Genetic Associations and Epidemiology
- Genetics and Neurodevelopmental Disorders
- Gene expression and cancer classification
- RNA regulation and disease
- Neurogenetic and Muscular Disorders Research
- RNA and protein synthesis mechanisms
- Soil and Water Nutrient Dynamics
- Cutaneous Melanoma Detection and Management
- Lung Cancer Research Studies
- Cancer-related molecular mechanisms research
- Maternal and fetal healthcare
- Hormonal Regulation and Hypertension
- Melanoma and MAPK Pathways
- Genetic diversity and population structure
- Genomics and Phylogenetic Studies
- Amyotrophic Lateral Sclerosis Research
- Genetic Mapping and Diversity in Plants and Animals
- Angiogenesis and VEGF in Cancer
First Affiliated Hospital of Harbin Medical University
2022
Harbin Medical University
2022
New Mexico Cancer Center
2018-2021
University of New Mexico
2018-2021
First Affiliated Hospital of Xi'an Jiaotong University
2021
UNM Comprehensive Cancer Center
2018
Baylor College of Medicine
2013-2017
Baylor Genetics
2015-2017
Peking University
2013
Peking University Third Hospital
2013
Triple-negative breast cancer (TNBC) is an operational term for cancers lacking targetable estrogen receptor expression and HER2 amplifications. TNBC is, therefore, inherently heterogeneous, associated with worse prognosis, greater rates of metastasis, earlier onset. displays mutational transcriptional diversity, distinct mRNA subtypes exhibiting unique biology. High-throughput sequencing has extended research far beyond protein coding regions that include non-coding small RNAs, such as...
Disturbances in amino acid metabolism are increasingly recognized as being associated with, and serving prognostic markers for chronic human diseases, such cancer or type 2 diabetes. In the current study, a quantitative metabolomics profiling strategy revealed global impairment mice deleted transcriptional coactivator steroid receptor (SRC)-1. Aberrations were hepatic origin, because selective reexpression of SRC-1 liver null largely restored acids concentrations to normal levels. Cistromic...
Atherosclerosis is the most notable cardiovascular disease, latter being main cause of death globally. Endothelial cell dysfunction plays a major role in pathogenesis atherosclerosis. However, it currently unclear which genes are involved between endothelial and This study was aimed at identifying these genes. Based on GSE83500 dataset, quantification function conducted using single-sample gene set enrichment analysis; coexpression modules were weighted correlation network analysis. After...
Objectives: Pseudogene interference is an issue for next generation sequencing (NGS) of homologous genes.The short length DNA fragments used in NGS methods makes assembly difficult to distinguish between the functional genes and highly pseudogenes.Succinate dehydrogenase complex, subunit A (SDHA) gene one example a with pseudogenes.Here, we present approach accurate molecular analysis SDHA gene.Methods: Seven samples, including wild-type control six samples known variants, were used.Primers...