Hui Yu

ORCID: 0000-0001-7232-968X
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About
Contact & Profiles
Research Areas
  • Genomics and Rare Diseases
  • Immunodeficiency and Autoimmune Disorders
  • Genomic variations and chromosomal abnormalities
  • RNA modifications and cancer
  • Cancer-related gene regulation
  • Bioinformatics and Genomic Networks
  • Kruppel-like factors research
  • Genetic Associations and Epidemiology
  • Genetics and Neurodevelopmental Disorders
  • Gene expression and cancer classification
  • RNA regulation and disease
  • Neurogenetic and Muscular Disorders Research
  • RNA and protein synthesis mechanisms
  • Soil and Water Nutrient Dynamics
  • Cutaneous Melanoma Detection and Management
  • Lung Cancer Research Studies
  • Cancer-related molecular mechanisms research
  • Maternal and fetal healthcare
  • Hormonal Regulation and Hypertension
  • Melanoma and MAPK Pathways
  • Genetic diversity and population structure
  • Genomics and Phylogenetic Studies
  • Amyotrophic Lateral Sclerosis Research
  • Genetic Mapping and Diversity in Plants and Animals
  • Angiogenesis and VEGF in Cancer

First Affiliated Hospital of Harbin Medical University
2022

Harbin Medical University
2022

New Mexico Cancer Center
2018-2021

University of New Mexico
2018-2021

First Affiliated Hospital of Xi'an Jiaotong University
2021

UNM Comprehensive Cancer Center
2018

Baylor College of Medicine
2013-2017

Baylor Genetics
2015-2017

Peking University
2013

Peking University Third Hospital
2013

Triple-negative breast cancer (TNBC) is an operational term for cancers lacking targetable estrogen receptor expression and HER2 amplifications. TNBC is, therefore, inherently heterogeneous, associated with worse prognosis, greater rates of metastasis, earlier onset. displays mutational transcriptional diversity, distinct mRNA subtypes exhibiting unique biology. High-throughput sequencing has extended research far beyond protein coding regions that include non-coding small RNAs, such as...

10.3390/genes9010029 article EN Genes 2018-01-10

Disturbances in amino acid metabolism are increasingly recognized as being associated with, and serving prognostic markers for chronic human diseases, such cancer or type 2 diabetes. In the current study, a quantitative metabolomics profiling strategy revealed global impairment mice deleted transcriptional coactivator steroid receptor (SRC)-1. Aberrations were hepatic origin, because selective reexpression of SRC-1 liver null largely restored acids concentrations to normal levels. Cistromic...

10.1210/me.2014-1083 article EN Molecular Endocrinology 2014-08-22

Atherosclerosis is the most notable cardiovascular disease, latter being main cause of death globally. Endothelial cell dysfunction plays a major role in pathogenesis atherosclerosis. However, it currently unclear which genes are involved between endothelial and This study was aimed at identifying these genes. Based on GSE83500 dataset, quantification function conducted using single-sample gene set enrichment analysis; coexpression modules were weighted correlation network analysis. After...

10.1155/2022/5544276 article EN cc-by BioMed Research International 2022-01-10

Objectives: Pseudogene interference is an issue for next generation sequencing (NGS) of homologous genes.The short length DNA fragments used in NGS methods makes assembly difficult to distinguish between the functional genes and highly pseudogenes.Succinate dehydrogenase complex, subunit A (SDHA) gene one example a with pseudogenes.Here, we present approach accurate molecular analysis SDHA gene.Methods: Seven samples, including wild-type control six samples known variants, were used.Primers...

10.1093/ajcp/aqw156.005 article EN American Journal of Clinical Pathology 2016-09-01
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