What, when, how, how much, and often infants are fed have been associated with childhood obesity risk. The objective of this secondary analysis was to examine the effect a responsive parenting (RP) intervention designed for prevention on parents' infant feeding practices in first year after birth. Primiparous mother-newborn dyads were randomized Intervention Nurses Start Infants Growing Healthy Trajectories (INSIGHT) Study RP or child safety control. Research nurses delivered content at home...

Objective To determine whether a responsive parenting (RP) intervention affects infant dietary patterns. Methods Primiparous mother‐newborn dyads ( n = 291) were randomized to the Intervention Nurses Start Infants Growing on Healthy Trajectories (INSIGHT) RP or control. Curricula delivered at nurse home visits ages 3, 16, 28, and 40 weeks. group feeding guidance advised feeding, delayed introduction of solids, repeated exposure novel foods, age‐appropriate portion sizes. Latent class...

Abstract Simultaneous and accurate measurement of vitamin D 25‐hydroxyvitamin in biological samples is a barrier limiting our ability to define “optimal” status. Thus, goal was optimize conditions evaluate an LC‐MS method for simultaneous detection quantification 2 , 3 serum. Extraction separation forms were achieved using acetone liquid–liquid extraction by reversed phase C8 column, respectively. Detection performed on triple quadrupole tandem mass spectrometer (QQQ‐MS/MS) equipped with...

The American Academy of Pediatrics recommends infant-parent room-sharing until age 1. We assessed the association between and sleep outcomes.The Intervention Nurses Start Infants Growing on Healthy Trajectories study is an obesity prevention trial comparing a responsive parenting intervention with safety control among primiparous mother-infant dyads. Mothers completed Brief Infant Sleep Questionnaire at 4, 9, 12, 30 months. Reported duration overnight behaviors, adjusted for group, were...

New food sources are needed to bridge the gap between vitamin D intake and recommended intake. We assessed bioavailability efficacy of in an 8 week dose−response study bread made with D2-rich yeast compared D3 growing, D-deficient rats. Plasma 25-hydroxyvitamin (25OHD) levels increased a curvilinear, dose-dependent manner both forms D, but rats fed achieved lower than D3. Rats highest doses had significantly greater (p < 0.05) trabecular BMC, BMD, bone volume, connectivity density, midshaft...

Abstract Childhood obesity represents a significant global health concern and identifying its risk factors is crucial for developing intervention programs. Many “omics” associated with the of have been identified, including genomic, microbiomic, epigenomic factors. Here, using sample 48 infants, we investigated how methylation profiles in cord blood placenta at birth were weight outcomes (specifically, conditional gain, body mass index, weight-for-length ratio) age six months. We...

High gestational weight gain is a major public health concern as it independently predicts adverse maternal and infant outcomes. Past interventions have had only limited success in effectively managing pregnancy gain, especially among women with overweight obesity. Well-designed are needed that take an individualized approach target unique barriers to promote healthy gain.The primary aim of the study describe protocol for Healthy Mom Zone, individually tailored, adaptive intervention...

Importance Behavioral interventions to treat childhood obesity have had limited success. Primary prevention is desirable, but whether intervention effectiveness can be sustained unknown. Objective To examine the effect of an designed for primary and delivered through age 2 years on weight outcomes 9 years. Design, Setting, Participants A longitudinal observation a single-center randomized clinical trial comparing responsive parenting vs home safety (control) among primiparous mother-child...

Abstract Introduction Poor sleep health is associated with childhood obesity, but the mechanisms underlying this association remain unclear. This study aimed to determine if variables are related daily frequency of eating in absence hunger (EAH), an obesogenic behavior, preadolescents. We hypothesized that children would be more likely engage EAH following nights shorter, later, or less efficient compared their usual sleep. Methods Children 8-12 years age (n=51) completed wrist actigraphy...

The Intervention Nurses Start Infant Growing on Healthy Trajectories (INSIGHT) study's responsive parenting (RP) intervention, initiated in early infancy, prevented the use of nonresponsive, controlling feeding practices and promoted structure-based among first-time parents compared with controls. We sought to examine spillover effect RP intervention maternal their secondborn (SB) infants enrolled an observational-only study, SIBSIGHT, test moderating spacing births. SB mothers participating...

Importance Black individuals in the US experience sleep disparities beginning infancy and continuing throughout lifespan, suggesting early interventions are needed to improve sleep. Objective To investigate whether a responsive parenting (RP) intervention for mothers improves infant increases practices. Design, Setting, Participants This is post hoc secondary analysis of Sleep SAAF (Strong African American Families) study, randomized clinical trial comparing an RP with safety control...

Infants higher on negative reactivity and lower regulation, aspects of temperament, have increased obesity risk. Responsive parenting (RP) has been shown to impact the expression including developing ability regulate emotions. The aim this analysis was test effects INSIGHT study's RP intervention designed for primary prevention reported observed infant negativity regulation.The sample included 240 mother-infant dyads randomized 2 weeks after birth or a safety control intervention. Both...

Metabolomic analysis is commonly used to understand the biological underpinning of diseases such as obesity. However, our knowledge gut metabolites related weight outcomes in young children currently limited.To (1) explore relationships between and child outcomes, (2) determine potential effect covariates (e.g., child's diet, maternal health/habits during pregnancy, etc.) relationship (3) selected microbiota abundance.Using 1 H-NMR, we quantified 30 from stool samples 170 two-year-old...

High gestational weight gain (GWG) in overweight/obese pregnant women increases maternal-fetal complications. We conducted a 6-week GWG intervention based on an energy balance model that includes theories of planned behavior (TPB) and self-regulation constructs to promote exercise healthy eating motivation behaviors. The purposes this proof-of-concept feasibility study were examine: (1) the over intervention, (2) pre-post weekly, dose-response changes constructs. Methods . Overweight/obese...

Peak bone mass accrual occurs during adolescence, a time when dieting and related eating behaviors are common. Impaired mineral is known consequence of disorders in adolescents, but the effects subclinical on content (BMC) have not been described this age group. The goal analysis was to determine whether behavior preadolescence adolescence associated with adolescent girls. Non-Hispanic white girls (n = 139) were followed longitudinal cohort study. BMC assessed at ages 9 15y. Dieting lose...

Excess maternal weight gain during pregnancy elevates infants' risk for macrosomia and early-onset obesity. Eating behavior is also related to gain, but the relationship fetal growth unclear. We examined whether Healthy Mom Zone, an individually tailored, adaptive gestational intervention, eating behaviors affected in pregnant women (n = 27) with a BMI > 24. At study enrollment (6-13 weeks gestation) monthly thereafter, Three-Factor Questionnaire was completed. Ultrasounds were obtained from...

Eating in the absence of hunger (EAH), a measure children's propensity to eat beyond satiety presence highly palatable food, has been associated with childhood obesity and later binge eating behavior. The EAH task is typically conducted research laboratory setting, which resource intensive lacks ecological validity. Assessing group classroom setting feasible may be more efficient alternative, but validity assessment against traditional individually-administered paradigm not tested. objective...

(1) Background: Energy intake (EI) underreporting is a widespread problem of great relevance to public health, yet poorly described among pregnant women. This study aimed describe and predict error in self-reported EI across pregnancy women with overweight or obesity. (2) Methods: Participants were from the Healthy Mom Zone study, an adaptive intervention regulate gestational weight gain (GWG) tested feasibility RCT followed (n = 21) body mass index (BMI) ≥25 8−12 weeks ~36 gestation. Mobile...

BACKGROUND AND OBJECTIVES The Intervention Nurses Start Infants Growing on Healthy Trajectories (INSIGHT) responsive parenting (RP) intervention for first-time mothers improved firstborn infant sleep compared with controls. goals of this analysis were to test spillover effects secondborn siblings and examine birth order differences in sleep. METHODS Secondborns (n = 117) INSIGHT enrolled an observational cohort, SIBSIGHT. Brief Infant Sleep Questionnaire was collected at 3, 16, 52 weeks....