A5004185933- Tuberculosis Research and Epidemiology
- COVID-19 diagnosis using AI
- Global Maternal and Child Health
- Mycobacterium research and diagnosis
- Global Health and Epidemiology
- Diagnosis and treatment of tuberculosis
- Pneumonia and Respiratory Infections
- HIV/AIDS Impact and Responses
- Global Public Health Policies and Epidemiology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Healthcare Systems and Reforms
- Child Nutrition and Water Access
- Lung Cancer Diagnosis and Treatment
- Viral Infections and Outbreaks Research
- Pharmaceutical studies and practices
- Radiomics and Machine Learning in Medical Imaging
- Pneumocystis jirovecii pneumonia detection and treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Adolescent and Pediatric Healthcare
Liverpool School of Tropical Medicine
2020-2022
Centre for Health Solutions
2016-2022
African Institute for Development Policy
2020-2022
African Institute for Development Policy
2020
Background We aimed to determine the prevalence of pulmonary TB amongst adult population (≥15 years) in 2016 Kenya. Method A nationwide cross-sectional survey where participants first underwent symptom screening and chest x-ray. Subsequently, who reported cough >2weeks and/or had a x-ray suggestive TB, submitted sputum specimen for laboratory examination by smear microscopy, culture Xpert MTB/RIF. Result The identified 305 prevalent cases translating 558 [95%CI 455–662] per 100,000...
Background The prevalence of diseases other than TB detected during chest X-ray (CXR) screening is unknown in sub-Saharan Africa. This represents a missed opportunity for identification and treatment potentially significant disease. Our aim was to describe quantify non-TB abnormalities identified by TB-focused CXR the 2016 Kenya National Prevalence Survey. Methods We reviewed random sample 1140 adult (≥15 years) CXRs classified as ‘abnormal, suggestive TB’ or ‘abnormal other’ field...
Despite high tuberculosis (TB) treatment success rate, adherence is one of the major obstacles to control in Kenya. Our objective was identify patient-related factors that were associated with time TB interruption and geographic distribution risk by county. Data new retreatment patients registered TIBU, a Kenyan national case-based electronic data recording system, between 2013 2014 obtained. Kaplan-Meier curves log rank tests used assess patterns. Mixed-effects Cox proportional hazards...
Community-based screening for tuberculosis (TB) could improve detection but is resource intensive. We set out to evaluate the accuracy of computer-aided TB using digital chest X-ray (CXR) determine if this approach met target product profiles (TPP) community-based screening. CXR images from participants in 2016 Kenya National Prevalence Survey were evaluated CAD4TBv6 (Delft Imaging), giving a probabilistic score pulmonary ranging 0 (low probability) 99 (high probability). constructed...
SETTING: One hundred high TB burden facilities in nine counties Kenya. OBJECTIVES: 1) To increase uptake of preventive therapy (TPT) among child contacts aged <5 years, and 2) to diagnosis children <15 years presenting health for routine care. DESIGN: For objective 1, a clinic-based contact management strategy incorporating transport/healthcare cost reimbursement, monitoring evaluation tools, healthcare worker education was utilized. 2, community screeners were established pediatric...
Devolution of healthcare services in Kenya resulted a large number newly recruited tuberculosis (TB) coordinators. We describe unique collaboration between national program (NTP), local, and an international non-governmental organization to build human resource capacity TB care prevention.From 2016 2021, the Division National Tuberculosis, Leprosy Lung Disease Program, Centre for Health Solutions-Kenya, International Union Against Tuberculosis developed conducted series 7-day training...
Abstract Background Community-based screening for tuberculosis (TB) could improve detection but is resource intensive. We set out to evaluate the accuracy of computer-aided TB using digital chest X-ray (CXR) determine if this approach met target product profiles (TPP) community-based screening. Methods CXR images from participants in 2016 Kenya National Prevalence Survey were evaluated CAD4TBv6 (Delft Imaging), giving a probabilistic score pulmonary ranging 0 (low probability) 99 (high...
Lung health is a critical area for research in sub-Saharan Africa. The International Multidisciplinary Programme to Address Health and TB Africa (IMPALA) collaborative programme that seeks fill evidence gaps address high-burden lung issues In order generate demand facilitate use of IMPALA by policy-makers other decision-makers at the regional level, an analysis policies stakeholders will be undertaken inform programmatic strategy policy engagement.This conducted three phases. first phase...
Background: The prevalence of diseases other than tuberculosis (TB) detected during chest X-ray (CXR) screening is unknown in sub-Saharan Africa. This represents a missed opportunity for identification and treatment potentially significant disease. Our aim was to quantify characterise non-TB abnormalities identified by TB-focused CXR the 2016 Kenya National TB survey. Methods: We reviewed random sample 1140 adult (≥15 years) CXRs classified as "abnormal, suggestive TB" or "abnormal other"...