Malcolm A. Buchanan

ORCID: 0000-0001-7355-0650
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About
Contact & Profiles
Research Areas
  • Tracheal and airway disorders
  • Voice and Speech Disorders
  • Sinusitis and nasal conditions
  • Head and Neck Surgical Oncology
  • Dysphagia Assessment and Management
  • Salivary Gland Tumors Diagnosis and Treatment
  • Nasal Surgery and Airway Studies
  • Head and Neck Cancer Studies
  • Streptococcal Infections and Treatments
  • Otolaryngology and Infectious Diseases
  • Soft tissue tumor case studies
  • Hearing, Cochlea, Tinnitus, Genetics
  • Airway Management and Intubation Techniques
  • Vestibular and auditory disorders
  • Thyroid Cancer Diagnosis and Treatment
  • Olfactory and Sensory Function Studies
  • Vascular Malformations and Hemangiomas
  • Cerebral Venous Sinus Thrombosis
  • Polyomavirus and related diseases
  • Cardiac tumors and thrombi
  • Bone Tumor Diagnosis and Treatments
  • Lymphadenopathy Diagnosis and Analysis
  • Ear Surgery and Otitis Media
  • Dermatological and COVID-19 studies
  • Neurofibromatosis and Schwannoma Cases

NHS Greater Glasgow and Clyde
2018-2023

Glasgow Royal Infirmary
2015-2023

Queen Elizabeth University Hospital
2018-2023

Oxford University Hospitals NHS Trust
2023

Westmead Hospital
2015-2016

Norfolk and Norwich University Hospital
2007-2015

The University of Sydney
2015

East and North Hertfordshire NHS Trust
2013

Lister Hospital
2010-2013

Peterborough City Hospital
2013

Transoral laser microsurgery (TLM) of the glottis is increasingly utilized in current management early glottic cancer, its advantages being administrative ease, potential to be repeated, ability keep radiotherapy and open laryngeal surgery available as salvage options, low complication rates.A retrospective chart review prospectively gathered data on all patients over a 10-year period who had undergone TLM for Tis or (T1-2) squamous cell carcinomas (SCCs) was analyzed examine complications...

10.1002/hed.24142 article EN Head & Neck 2015-06-04

10.1016/j.paed.2011.12.002 article EN Paediatrics and Child Health 2012-01-25

Introduction . Internal nasal valve incompetence (INVI) has been treated with various surgical methods. Large, single surgeon case series are lacking, meaning that the evidence supporting a particular technique deficient. We present using alar batten grafts to reconstruct internal valve, all performed by senior author. Methods Over 7-year period, 107 patients obstruction caused INVI underwent grafting. Preoperative assessment included use of strips evaluate symptom improvement. Visual...

10.1155/2013/734795 article EN International Journal of Otolaryngology 2013-01-01

Abstract Introduction: The Hayes-Martin manoeuvre involves ligation of the posterior facial vein and superior reflection investing fascia below mandible to preserve marginal mandibular nerve. peri-facial nodes thus remain undissected. We perform this routinely during modified radical neck dissection for metastatic oropharyngeal squamous cell cancer. Here, we review oncological safety nerve preservation rates from 2004 2009. Method: Retrospective head oncology database (2004–2009) at...

10.1017/s0022215112001740 article EN The Journal of Laryngology & Otology 2012-08-21

To ascertain whether local anaesthetic use is of clinical benefit in nasal surgery, a prospective double-blind randomized controlled trial topical bupivacaine on post-operative pain patients packed after bilateral surgery was carried out. Each patient received bupivacaine-soaked and saline-soaked Merocel pack, thereby acting as their own control. Power analysis ascertained the number required to enter detect statistically significant difference pain. Fifty-seven completed trial. Visual...

10.1258/0022215054020322 article EN The Journal of Laryngology & Otology 2005-04-01

In goiter, increased expression of growth factors and their receptors occurs. We have inhibited the action some these factors, alone in combination, to determine which are important goitrogenesis. Recombinant adenovirus vectors (RAds) expressing truncated, secreted forms human Tie2 (RAd-sTie2) vascular endothelial factor receptor 1 (RAd-sVEGFR1) or a dominant-negative fibroblast (RAdDN-FGFR1) were used. Goiters mice induced by feeding an iodide-deficient diet, containing methimazole sodium...

10.1210/en.2005-0168 article EN Endocrinology 2005-04-08

The carbon dioxide laser can induce thermal cytologic artifacts at the margin of early glottic squamous cell carcinoma histologic specimens, which makes assessment difficult. This study assesses and correlates depth laser-induced artifact with power rating.The surgical margins 30 patients carcinomas who underwent resection were reanalyzed retrospectively.Thermal damage consisted collagen denaturation within vocal cord lamina propria vocalis muscle, epithelial structural changes. There was a...

10.1002/hed.24076 article EN Head & Neck 2015-04-20

Abstract Objective: To determine whether there is a change in the epidemiology of nasal fractures females UK, and potential contribution ‘ladette’ culture. Methods: This paper reports multi-centre retrospective study. Operating theatre data for all who underwent manipulation under anaesthesia between 2002 2009 were analysed. In addition, case notes presenting with over five-year period (2004–2009) retrospectively reviewed cited cause fracture was noted. Results: From to 2009, an 825 per cent...

10.1017/s0022215113002260 article EN The Journal of Laryngology & Otology 2013-10-17

Abstract Introduction: Intramuscular haemangiomas of the digastric muscle are often misdiagnosed due to their low incidence and non-specific manifestation. Only two out six previously reported cases were diagnosed correctly before excision. Ultrasound may not reveal vascularity, fine-needle aspiration biopsy is unhelpful as it reveals only blood. Methods: A case intramuscular haemangioma posterior belly described. Previously reviewed. Investigations used diagnose lesions reasons for common...

10.1017/s0022215111003161 article EN The Journal of Laryngology & Otology 2012-01-19

A total laryngectomy creates an alternate airway for gas exchange that bypasses the upper aerodigestive tract. The subsequent reduction in nasal airflow, and therefore, deposition of particles to olfactory neuroepithelium leads hyposmia or anosmia. aim this study was assess quality life impairment conferred by anosmia following identify any specific patient-related risk factors are associated with poorer outcomes.Consecutive patients a presenting review at three tertiary head neck services...

10.1007/s00405-023-07976-0 article EN cc-by European Archives of Oto-Rhino-Laryngology 2023-04-28

Background . VEGF exerts its effects by binding to tyrosine kinase receptors, KDR and VEGFR1. is critical for transmitting signals proliferation of endothelial cells but also expressed in several non‐endothelial suggesting existence autocrine stimulatory pathways. Study‐design We investigated expression human thyroid epithelial vitro cancers samples ex vivo Results Expression was demonstrated using Taqman RT‐PCR Western blotting a follicular cancer line (FTC133) primary cells. Further,...

10.1111/j.1749-4486.2006.01236_6.x article EN Clinical Otolaryngology 2006-05-23

Abstract Objective: To describe an unusual case of lateral neck swelling in a patient with permanent cardiac pacemaker. Case report: We who presented painful, due to internal jugular vein thrombus. This thrombus originated from around pacemaker wires the subclavian vein. is unusual, as vast majority thromboses patients pacemakers are found alone. also review literature on relationship between and thrombosis, management latter. Conclusion: Our illustrates rare cause swelling: secondary...

10.1017/s0022215110000046 article EN The Journal of Laryngology & Otology 2010-02-16

Abstract Objectives: To evaluate patient satisfaction and symptom improvement following treatment of Ménière's disease with the Meniett ® device. Methods: Retrospective, questionnaire-based audit analysis unilateral patients’ records, on from a previous study our departments intra-tympanic gentamicin for disease, using Vertigo Symptom Scale Glasgow Benefit Inventory as outcome measures. Results: Of 33 consecutive patients treated device four to six weeks, 30 responded questionnaires (90.9...

10.1017/s0022215110001118 article EN The Journal of Laryngology & Otology 2010-06-11

Chemotherapy increases susceptibility to infection due the effect on cell-mediated and humoral immunity. Retropharyngeal abscess is a serious head neck that rapidly progresses from toxicity, whether patient neutropenic or not. The risk should be carefully assessed with any chemotherapeutic agent, especially docetaxel.

10.1136/bcr-2017-222610 article EN BMJ Case Reports 2018-03-05

M A Buchanan and colleagues investigate the possible hazards of modern drivers A 55 year old right handed man presented to ear, nose, throat outpatient clinic with tinnitus reduced hearing in his ear. Clinical examination was unremarkable. His pure tone audiogram showed an asymmetrical sensorineural loss, worse on right, a decrease that side at 4-6 kHz (fig 1⇓) typical noise induced loss.1 He had been playing golf King Cobra LD titanium club three times week for 18 months commented hitting...

10.1136/bmj.a2835 article EN BMJ 2008-12-17

Abstract Objective: To present a previously unreported cause of frontal mucocele. Case report: A patient presented with mucocele and maxillary sinusitis. Computed tomography revealed an ectopic tooth as the her signs symptoms. Removal by Caldwell–Luc procedure facilitated resolution Conventional treatment mucoceles endoscopic sinus surgery, other rhinological sequelae teeth, are considered. Conclusion: This is first documented case causing mucocele, demonstrates how effectively patient's...

10.1017/s002221510700062x article EN The Journal of Laryngology & Otology 2007-09-25
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