- Mast cells and histamine
- Allergic Rhinitis and Sensitization
- Urticaria and Related Conditions
- Food Allergy and Anaphylaxis Research
- Parvovirus B19 Infection Studies
- Asthma and respiratory diseases
- Genetic and rare skin diseases.
- Vascular Malformations and Hemangiomas
- Neonatal skin health care
- Dermatology and Skin Diseases
- Tumors and Oncological Cases
- Skin and Cellular Biology Research
- melanin and skin pigmentation
- Dermatological and COVID-19 studies
- Streptococcal Infections and Treatments
- Soft tissue tumor case studies
- Autoimmune and Inflammatory Disorders
- Gastrointestinal disorders and treatments
- Contact Dermatitis and Allergies
- Hair Growth and Disorders
- Drug-Induced Adverse Reactions
- Chronic Lymphocytic Leukemia Research
- Respiratory and Cough-Related Research
- Genital Health and Disease
- Cutaneous lymphoproliferative disorders research
Vrije Universiteit Brussel
2021-2025
Onze Lieve Vrouwziekenhuis Hospital
2014-2025
Universitair Ziekenhuis Brussel
2021-2025
Flanders Environment Agency
2018
National and Kapodistrian University of Athens
2000-2003
Andreas Sygros Hospital
2003
Erasmus University Rotterdam
2001
Adult and Pediatric Dermatology
1996
Mundipharma (Netherlands)
1996
Erasmus MC - Sophia Children’s Hospital
1996
Seventeen cases of collodion baby are reported. Clinical aspects, complications, treatment, final outcome and family history were studied. We did not observe any clinical features in the that could serve as a clue predicting diagnosis. Infections observed nine, hypothermia five hypernatraemic dehydration four cases. Skin infection mainly occurred babies treated with emollients (petrolatum, lanolin cetomacrogolis cream used). therefore recommend treating humidified incubator, if necessary...
Mastocytosis is characterized by an increased number of mast cells with abnormal growth and accumulation in one or more organs. In most children mastocytosis limited to the skin (cutaneous mastocytosis) often transient as compared that adults whom usually progressive systemic. Generally, we recognize three common forms cutaneous mastocytosis: maculopapulous (formerly urticaria pigmentosa), mastocytoma skin, diffuse mastocytosis. Childhood can further be divided into (nonpersisting...
Boys run a higher risk for atopy than girls but this gender difference is less pronounced in adulthood. The underlying mechanisms and the exact timing of decrease male/female ratio remain unclear. aim study was to evaluate effect age on sensitization schoolchildren. A cross‐sectional performed an unbiased community population 2021 Belgian schoolchildren, aged 3.4–14.8 yr. overall mites, mixed grass pollens tree increased significantly with increasing age. Male sex strongly associated (OR adj...
<i>Objective:</i> This paper describes two different clinical presentations of diffuse cutaneous mastocytosis (DCM), based on the largest series published to date. As far as we are aware, these variants have not yet been reported. <i>Design:</i> We undertook a case controlled analysis 8 children with DCM. Results laboratory testing including mast cell mediator levels, and symptoms presentation during follow-up were analyzed. <i>Results:</i> The levels...
We report a 14-year-old boy with Stevens-Johnson syndrome who presented mucous membrane lesions but without skin and discuss the differential diagnosis of oral in childhood. children is most frequently caused by Mycoplasma pneumoniae infection. The full clinical picture can be present before seroconversion antibodies observed. One should keep mind that one negative titer does not rule out M.
Results of studies the influence body mass index (BMI) on allergic status are controversial. As a part Aalst Allergy Study, we assessed prevalence different BMI categories (underweight, normal weight, overweight, and obesity) possible association between atopy in 1576 unselected Belgian schoolchildren, aged from 3.4 to 14.8 yr. was used determine weight status. Skin prick testing with most common aeroallergens performed. A parental questionnaire documented data respiratory disorders,...
IgE‐mediated contact urticaria syndrome (CUS) is one of the manifestations allergy in childhood atopic dermatitis (AD). Allergens such as foods and animal products penetrate skin easily. They can then cause urticarial reactions sensitized individuals. A provocation test system for foods, called application food (SAFT), has been developed. Over more than 5 years, a group 175 patients with AD was built‐up investigated prospective follow‐up study SAFT. SAFT frequently positive children aged 6–2...
Although it is generally agreed that sensitization an important risk factor for allergic diseases, the extent to which accounts symptoms in children controversial. As part of Aalst Allergy Study, this cross‐sectional study investigated prevalence and their association with unselected population Flemish aged 3.4–14.8 yr. Skin prick testing most common aeroallergens was performed were documented by a parental questionnaire. In older than 6 yr, significant current wheezing, dyspnea, airway...
Comèl-Netherton syndrome (CN) is characterized by atopic-eczema-like skin abnormalities combined with linear ichthyotic lesions, hair shaft and atopy high IgE levels.Five children CN are described. In 2 of the 3 patients still alive, analysis cytokines regulating synthesis was performed.In peripheral blood mononuclear cells cultures purified T cells, mRNA expression protein production interleukin 4 (IL-4), IL-13, IL-5 interferon gamma were analysed. The results compared values in age-matched...
We report a patient with phakomatosis pigmentovascularis IIb and numerous iris hamartomas. Phakomatosis is characterized by the simultaneous occurrence of nevus flammeus, mongolian spot, sometimes anemicus in same individual, systemic involvement. To our knowledge, association multiple hamartomas has been reported only once. This second suggests that might be more common. Additional reports will indicate if such an frequent than now assumed.
Abstract: Childhood eczema is common in infants, but its nature and extent during later childhood remains unclear. In this cross‐sectional study we examined the prevalence characteristics of an unbiased community population 2,021 Belgian schoolchildren, aged 3.4 to 14.8 years with skin prick testing parental questionnaires. Our identified 23.3% a considerable allergic co‐morbidity, mainly sensitized children. The reported infancy was 18.5% for current 11.6%. overall sensitization rate...