Daniela‐Saveta Popa

ORCID: 0000-0001-7449-5753
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About
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Research Areas
  • Nuts composition and effects
  • Phytochemicals and Antioxidant Activities
  • Antioxidant Activity and Oxidative Stress
  • Analytical Methods in Pharmaceuticals
  • Forensic Toxicology and Drug Analysis
  • Phytoestrogen effects and research
  • Carcinogens and Genotoxicity Assessment
  • Effects and risks of endocrine disrupting chemicals
  • Pharmacogenetics and Drug Metabolism
  • Epilepsy research and treatment
  • Pharmacological Effects and Assays
  • Antibiotics Pharmacokinetics and Efficacy
  • Tea Polyphenols and Effects
  • Estrogen and related hormone effects
  • Analytical Chemistry and Chromatography
  • Bee Products Chemical Analysis
  • Pharmacological Effects and Toxicity Studies
  • Diet and metabolism studies
  • Anesthesia and Sedative Agents
  • Metabolomics and Mass Spectrometry Studies
  • Vitamin C and Antioxidants Research
  • Pesticide Exposure and Toxicity
  • Microbial Metabolites in Food Biotechnology
  • Pesticide Residue Analysis and Safety
  • Neuroscience and Neuropharmacology Research

Iuliu Hațieganu University of Medicine and Pharmacy
2015-2024

Plant by-products can be valuable sources of polyphenol bioactive compounds. Walnut (Juglans regia L.) is a very important tree nut rich in biologically active molecules, but its septum was scarcely researched. Experimental data indicated hypoglycemic effect extracts, with almost no details about phytochemical composition. The main objectives this study were: (1) to obtain walnut (WS) extracts high content compounds and antioxidant activity based on an original experimental design; (2)...

10.3390/molecules23112814 article EN cc-by Molecules 2018-10-30

Antioxidant dietary intervention is considered a potential strategy in delaying age-related dysfunctions. In this study of 56 days, we assessed the antioxidant effects walnut kernel (WK) and septum extract (WSE) D-galactose (D-gal)-induced aging model naturally aged rat model. Young Wistar rats, treated with D-gal (1200 mg/week), old rats received daily WK or WSE added to feed. After 8 weeks, blood, liver, brain samples were collected hematological, biochemical, oxidative stress biomarkers,...

10.3390/antiox9050424 article EN cc-by Antioxidants 2020-05-14

Tree nut by-products could contain a wide range of phytochemicals, natural antioxidants, which might be used as source for dietary supplements. The aim the present study was to evaluate phenolic and sterolic composition, well antioxidant other biological activities, hazelnut involucre (HI) extracts. Experimental designs were developed in order select optimum extraction conditions (solvent, temperature, time) using turbo-extraction by Ultra-Turrax obtaining extracts rich bioactive compounds....

10.3390/antiox8100460 article EN cc-by Antioxidants 2019-10-08

The extraction of bioactive compounds present in walnut (Juglans regia L.) male flowers (WMFs) was performed based on an experimental design using ultrasonic-assisted extraction. Solvent nature, time, and water content were selected as variables, phenolic, flavonoidic, condensed tannins contents antioxidant properties evaluated. Acetone the solvent with highest performance, extracts obtained this displaying increased concentration activities. For several high content, individual polyphenolic...

10.3390/antiox10040607 article EN cc-by Antioxidants 2021-04-15

The antitussive, antioxidant, and anti-inflammatory effects of a walnut (Juglans regia L.) septum extract (WSE), rich in bioactive compounds were investigated using the citric acid aerosol-induced cough experimental model rodents. Wistar male rats treated orally for three days with distilled water (control), codeine (reference), WSE graded doses. On third day, all exposed to aerosols, number coughs being recorded. Each animal was sacrificed after exposure, blood lung tissue samples collected...

10.3390/antiox10010119 article EN cc-by Antioxidants 2021-01-15

This study explores the bioactive potential of young shoots from blackcurrant, European blueberry, and mountain cranberry, widely employed in gemmotherapy phytotherapy, as rich sources antioxidants, antimicrobial agents, anti-inflammatory components. The primary aims this were to enhance extraction conditions for compounds blackcurrant using Modde software experimental design, conduct a comprehensive phytochemical analysis cranberry shoot extracts through LC–MS analysis, evaluate vitro...

10.3390/horticulturae9111163 article EN cc-by Horticulturae 2023-10-24

In recent years, it has been increasingly suggested that the consumption of natural polyphenols, in moderate amounts, is beneficial for health. The aim this study was to investigate efficacy a red wine (the administered dose 7 mL/kg/day being equivalent ~16.5 mg/kg/day total polyphenols) compared white ~1.7 polyphenols), on prevention acrylamide-induced subacute hepatic injury and oxidative stress Wistar rats. Hepatic damage due acrylamide intoxication 250 µg/kg body weight, 28 days, by...

10.3390/antiox11071347 article EN cc-by Antioxidants 2022-07-10
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