A5084450352- Pancreatic function and diabetes
- Infectious Aortic and Vascular Conditions
- Microfluidic and Capillary Electrophoresis Applications
- Receptor Mechanisms and Signaling
- Hemostasis and retained surgical items
- CAR-T cell therapy research
- Aquaculture disease management and microbiota
- Mosquito-borne diseases and control
- Nanoplatforms for cancer theranostics
- Aortic Disease and Treatment Approaches
- Electrospun Nanofibers in Biomedical Applications
- Graphene and Nanomaterials Applications
- Erythrocyte Function and Pathophysiology
- Vascular Malformations and Hemangiomas
- Metabolism, Diabetes, and Cancer
- Aortic aneurysm repair treatments
- Vibrio bacteria research studies
- Moyamoya disease diagnosis and treatment
University of Southern California
2020-2024
Terasaki Foundation
2022-2023
Subcellular maps of β cells reveal the coordinated reorganization organelles during insulin secretion.
Abstract Sac embolization of abdominal aortic aneurysms (AAAs) remains clinically limited by endoleak recurrences. These recurrences are correlated with recanalization due to the presence endothelial lining and matrix metalloproteinases (MMPs)‐mediated aneurysm progression. This study incorporates doxycycline (DOX), a well‐known sclerosant MMPs inhibitor, into shear‐thinning biomaterial (STB)‐based vascular embolizing hydrogel. The addition DOX is expected improve efficacy while preventing...
Shear-thinning biomaterials (STBs) based on gelatin-silicate nanoplatelets (SNs) are emerging as an alternative to conventional coiling and clipping techniques in the treatment of vascular anomalies. Improvements cohesion STB hydrogels pave way toward their translational application minimally invasive therapies such endovascular embolization repair. In present study, sodium phytate (Phyt) additives used tune electrostatic network SNs-gelatin STBs, thereby promoting mechanical integrity...
Inside Back Cover: Gelatin-silicate nanoplatelets have leveraged shear-thinning biomaterial (STB) systems as an alternative to coiling and clipping for the treatment of vascular anomalies through minimally invasive procedures. Occlusion aneurysms depends on stability hemostatic efficacy STB. Introducing sodium phytate in nanoplatelets-based STBs enables major improvements cohesion effects a more effective therapeutic effect endovascular embolization repair. This is reported by Alireza...
Insulin is a peptide hormone secreted from pancreatic beta cells to regulate blood glucose homeostasis. Maturation of active insulin occurs within secretory granules (ISG) by acidification the lumen and enzymatic cleavage before secretion. This process dysregulated in diabetes, many questions remain on how cell controls maturation. We address this gap knowledge designing two genetically encoded fluorescence pH sensors lifetime imaging analysis pipeline monitor individual ISGs live at higher...