Carla Griffiths

ORCID: 0000-0001-7612-7823
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About
Contact & Profiles
Research Areas
  • Single-cell and spatial transcriptomics
  • Hearing, Cochlea, Tinnitus, Genetics
  • Hearing Loss and Rehabilitation
  • Cancer-related molecular mechanisms research
  • Music and Audio Processing
  • Urinary and Genital Oncology Studies
  • Head and Neck Surgical Oncology
  • Sinusitis and nasal conditions
  • Bladder and Urothelial Cancer Treatments
  • Vascular Anomalies and Treatments
  • Neural dynamics and brain function
  • Neural Networks and Applications
  • Advanced Radiotherapy Techniques
  • Marine animal studies overview
  • Digital Media Forensic Detection
  • Animal Vocal Communication and Behavior
  • Colorectal Cancer Screening and Detection
  • Blood Pressure and Hypertension Studies

University College London
2023-2024

National Institute on Deafness and Other Communication Disorders
2019

National Institutes of Health
2019

University of Oxford
2015

University of Santa Monica
2012

The stria vascularis (SV) generates the endocochlear potential (EP) in inner ear and is necessary for proper hair cell mechanotransduction hearing. While channels belonging to SV types are known play crucial roles EP generation, relatively little about gene regulatory networks that underlie ability of generate maintain EP. Using single nucleus RNA-sequencing, we identify validate rare populations SV. Furthermore, establish a basis understanding molecular mechanisms underlying function by...

10.3389/fnmol.2019.00316 article EN cc-by Frontiers in Molecular Neuroscience 2019-12-20

Animal psychophysics can generate rich behavioral datasets, often comprised of many 1000s trials for an individual subject. Gradient-boosted models are a promising machine learning approach analyzing such data, partly due to the tools that allow users gain insight into how model makes predictions. We trained ferrets report target word’s presence, timing, and lateralization within stream consecutively presented non-target words. To assess animals’ ability generalize across pitch, we...

10.1371/journal.pcbi.1011985 article EN cc-by PLoS Computational Biology 2024-04-16

Abstract The stria vascularis (SV) generates the endocochlear potential (EP) in inner ear and is necessary for proper hair cell mechanotransduction hearing. While channels belonging to SV types are known play crucial roles EP generation, relatively little about gene regulatory networks that underlie ability of generate maintain EP. Using single nucleus RNA-sequencing, we identify validate rare populations SV. Furthermore, establish a basis understanding molecular mechanisms underlying...

10.1101/756635 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2019-09-04

ABSTRACT Animal psychophysics can generate rich behavioral datasets, often comprised of many 1000s trials for an individual subject. Gradient-boosted models are a promising machine learning approach analyzing such data, partly due to the tools that allow users gain insight into how model makes predictions. We trained ferrets report target word’s presence, timing, and lateralization within stream consecutively presented non-target words. To assess animals’ ability generalize across pitch, we...

10.1101/2023.06.16.545302 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-06-21

Background: Unilateral “rescue flap,” without anterior dissection, has been described in the literature. It ensures preservation of posterior septal artery pedicle lest a nasoseptal flap is required for closure at end procedure. Herein we present series patients who have undergone transsphenoidal surgery which performed mucosal preserving bilateral rescue flaps over sphenoid rostrum during approach to sinus.

10.1055/s-0032-1313977 article EN Journal of Neurological Surgery Part B Skull Base 2012-05-02
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