A5101799230- Mycobacterium research and diagnosis
- Reproductive System and Pregnancy
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Pregnancy and Medication Impact
- Nuclear Receptors and Signaling
- Renal Diseases and Glomerulopathies
- Galectins and Cancer Biology
- Vasculitis and related conditions
- Drug-Induced Hepatotoxicity and Protection
- Emotion and Mood Recognition
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Gut microbiota and health
- Sphingolipid Metabolism and Signaling
- Sleep and Wakefulness Research
- Immune Cell Function and Interaction
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Apelin-related biomedical research
- Preterm Birth and Chorioamnionitis
- Obstructive Sleep Apnea Research
- Dialysis and Renal Disease Management
- Adolescent and Pediatric Healthcare
- Protein Tyrosine Phosphatases
- Pharmacological Effects and Toxicity Studies
- Drug Transport and Resistance Mechanisms
Chinese PLA General Hospital
2021-2025
Nanjing Medical University
2011-2021
Wuxi No.2 People's Hospital
2021
Second Affiliated Hospital of Nanjing Medical University
2021
Nanjing Brain Hospital
2020
Nanjing Chest Hospital
2020
Shandong Provincial Hospital
2020
Shandong University
2020
Model Animal Research Center
2011
Nanjing University
2011
Gut dysbiosis is associated with chronic kidney disease (CKD), and serum free immunoglobulin light chains (FLCs) are biomarkers for CKD. This study aims to assess the CKD gut microbiome determine its impact on FLC levels.To control confounders, 100 patients sex- age-matched healthy controls (HCs) were recruited. The was assessed by sequencing 16S rRNA gene V3-V4 hypervariable regions. Phylogenetic Investigation of Communities Reconstruction Unobserved States applied infer functional...
Objectives: The etiology and pathogenesis of recurrent implantation failure (RIF) remain unclear. This study aimed to delineate the immune landscape identify pivotal biomarkers dysregulation in RIF. Methods: Comprehensive bioinformatics analyses, including differential expression, functional enrichment, gene set weighted co-expression network analysis, protein-protein interaction network, machine learning were conducted explore immunological underpinnings Results: Our findings demonstrated a...
Abstract Apela was recently identified as a new ligand of the apelin peptide jejunum (APJ) receptor. The purpose this study to investigate role apela in post‐myocardial infarction (post‐MI) recovery from cardiorenal damage. A murine MI model established, and then infused subcutaneously for two weeks. Echocardiographs were performed before after at indicated times. Renal function evaluated by serum urine biochemistry. Immunohistochemistry heart kidney tissue situ terminal deoxynucleotidyl...
Abstract Background Tuberculosis remains an important disease threatening the security of public health, and no effective targets have been found for immunological diagnosis or therapy tuberculosis. The aim this study was to explore associations between lncRNA CASC8 genetic polymorphism tuberculosis risk. Method A total 900 patients 1534 healthy individuals in Western Chinese Han population were recruited our study. Candidate SNPs initially filtered by importing 1000 genomes database into...
Tuberculosis (TB) remains a major public health problem. Long non-coding RNAs (lncRNAs) are important regulators of gene expression. In this study, we explored the association between expression lncRNA AC007128.1 and TB susceptibility.Three single-nucleotide polymorphisms (SNPs) (rs12333784, rs6463794, rs720964) were selected using 1000 Genomes Project database offline software Haploview V4.2, genotyped by customized 2×48-Plex SNPscan™ Kit.We identified two differentially expressed including...
Study Objectives: People show a facial recognition speed advantage, termed positive classification advantage (PCA), when judging whether expression is happy compared to angry or sad.This study investigated emotional face by patients with obstructive sleep apnea (OSA) impaired neurocognition.Methods: Thirty-four OSA and 26 healthy control who underwent 1 night of polysomnographic evaluation before recruitment were asked complete an emotion task.Accuracy rates reaction times recorded analyzed...
What is known and objective Combination regimens of six-month duration may increase the incidence anti-tuberculosis drug-induced liver injury (ATLI), which clinically characterized by mild cholestasis hepatocanalicular lesions. UGT2B4 a predominant UDP-glucuronosyltransferase enzyme in human that plays an important role detoxification bile acids, yields water-soluble inactive compounds can easily be excreted or urine. This study aimed to investigate potential association between variants...