- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Medical Imaging and Pathology Studies
- Tracheal and airway disorders
- Lung Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- MXene and MAX Phase Materials
- Long-Term Effects of COVID-19
- Endometriosis Research and Treatment
- Respiratory Support and Mechanisms
- Systemic Sclerosis and Related Diseases
- Obstructive Sleep Apnea Research
- Sepsis Diagnosis and Treatment
- Pneumonia and Respiratory Infections
- Chronic Myeloid Leukemia Treatments
- Vasculitis and related conditions
- Electrolyte and hormonal disorders
- Peripheral Neuropathies and Disorders
- Infectious Diseases and Mycology
- Muscle and Compartmental Disorders
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Urological Disorders and Treatments
- Intensive Care Unit Cognitive Disorders
- Superconducting Materials and Applications
- Surgical Simulation and Training
St. Luke's International Hospital
2019-2025
The Princess Grace Hospital
2024
Endometriosis
2024
National Cancer Center Hospital East
2022-2023
National Center for Global Health and Medicine
2022
Novartis (Switzerland)
2009
Abstract We report a case series of seven mechanically ventilated patients with acute respiratory distress syndrome (ARDS) caused by coronavirus disease (COVID‐19) who received early treatment high‐dose, short‐term systemic corticosteroids to prevent cytokine overproduction. Of the patients, four were male and median age was 69 years. They intubated within days after admission when their status rapidly worsened. At that time, we administered 1000 or 500 mg/day for three methylprednisolone...
Background Although antifibrotic agents (AFAs) are often discontinued due to side effects, their tolerability is crucial given the limited treatment options for interstitial lung disease associated with connective tissue (CTD-ILD). The possibility of intolerance organ damage caused by CTDs has also been considered; however, few detailed studies available. We hypothesized that AFAs CTD-ILD would be poorly tolerated or prematurely collagen disease. Therefore, we conducted a retrospective...
Abstract The Pfizer‐BioNTech mRNA vaccine (BNT162b2) is an effective and well‐tolerated coronavirus disease 2019 (COVID‐19) vaccine. However, rare adverse events have been reported. We report two cases of COVID‐19 vaccine‐related interstitial lung (ILD). A 67‐year‐old man a 70‐year‐old with underlying ILD presented to our hospital few days fever respiratory symptoms after receiving the BNT162b2 Drug‐related pneumonitis due was diagnosed. One case diagnosed lymphocytic alveolitis by...
Background Imatinib is the standard of care for newly diagnosed chronic-phase chronic myeloid leukemia. The largest randomized clinical trial imatinib was multinational IRIS in which 1106 patients were to receive either 400 mg/day or a regimen interferon-α plus cytarabine.Design and Methods Patients allowed cross over opposite treatment intolerance, lack response, disease progression, and, following release initial efficacy data, reluctance remain on therapy with cytarabine. safety who...
Background: Endobronchial ultrasound (EBUS)-guided intranodal forceps biopsy (IFB), a diagnostic bronchoscopic technique for intrathoracic lymphadenopathy, is performed following EBUS-guided transbronchial needle aspiration (TBNA). The current EBUS-IFB complex and provides small sample volumes. We modified this to allow the use of standard-sized forceps. Objectives: aim study was assess feasibility technique, which combines with standard EBUS-TBNA equipment. Method: This retrospective...
Rationale: Equivocal interstitial lung abnormality (ILA) involves less than 5% of any zone or presents unilaterally without satisfying the diagnostic criteria for ILA. However, prevalence and prognosis equivocal ILA are unknown. Objectives: We sought to investigate long-term Methods: This retrospective cohort study included individuals who underwent chest computed tomography as part a health check-up program in 2010 at St. Luke's International Hospital Tokyo, Japan. were diagnosed using...
Corticosteroids have been reported to reduce the mortality rates in patients with coronavirus disease 2019 (COVID-19). Additionally, role of high-dose methylprednisolone pulse therapy reducing critically ill has also documented. The purpose this study is identify COVID-19 who are suitable for therapy.This was a retrospective that included receiving (≥250 mg/day 3 days) subsequent tapering doses at our hospital between June 2020 and January 2021. We examined differences background clinical...
Refractory pneumothorax associated with interstitial lung disease (ILD) remains a challenging condition due to the patient's tolerability and compliance that restrict feasibility of aggressive interventions. Additionally, many cases recur after improvement treatment, reports successful management for this complicated are limited. Herein, we report case 60-year-old man ILD, utilizing home oxygen therapy, who experienced recovery from surgical intervention under local anaesthesia pneumothorax....
Abstract Aim Thoracic endometriosis syndrome (TES) is underdiagnosed, due to cyclical thoracic symptoms being underreported. Management of TES also remains controversial, with abdominal and approaches proposed, both laparoscopically robotically, no guidelines available. We aimed characterise our experience a multidisciplinary, robot-assisted approach, focus on symptom prevalence surgical outcomes. Method A retrospective review all consecutive procedures for between July 2020 March 2023...
We report a case of 57-year-old woman with pulmonary metastasis breast cancer presenting characteristic cavitary shadow resembling aspergilloma. The primary tumor and metastases showed multiple histopathologic components, including squamous cell carcinoma. Although fungal ball-like may indicate the presence aspergilloma, comprehensive examination, bronchoscopy, should be considered.
Abstract Background Although diffuse alveolar damage (DAD) is a histopathological hallmark of acute respiratory distress syndrome (ARDS), its detection without lung biopsy challenging. In patients with ARDS, the specificity Berlin definition to diagnose DAD as reference standard not adequately high, making it difficult DAD. The purpose this study was investigate relationship between and clinical findings, including KL-6 geographic appearance, in ARDS identify more specific diagnostic...
An 87-year-old woman who had undergone coil embolization 25 years ago for pulmonary arteriovenous fistula, which was diagnosed following repeated cerebral infarction, presented with massive hemoptysis. The coils migrated and were excreted in stool hemoptysis during long-term follow-up. Although the technical success rate of malformations is extremely high, embolization-related complications are rare, little known about complications. We herein report clinical course our case, review previous...
Li-Fraumeni syndrome (LFS) is a rare familial disorder caused by germline TP53 mutations. Despite the establishment of revised Chompret criteria to guide genetic testing for TP53, identifying LFS in patients who do not satisfy these remains challenge. Herein, we present case 50-year-old woman with history breast, lung, colorectal, and tongue cancers did criteria. However, ultimately revealed mutation, leading diagnosis LFS. Although her family classic criteria, she had core tumor before age...
Background: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is recommended for nodal staging in non-small cell lung cancer (NSCLC). Although this method may rarely fail, reports on the causes are few. We therefore retrospectively investigated factors causing failure of by EBUS-TBNA. Methods: Consecutive patients who underwent EBUS-TBNA at National Cancer Center Hospital between January 2017 and December 2020 systematic NSCLC were extracted. The stages diagnosis...
Abstract Background Bowel endometriosis impacts quality of life. Treatment requires complex surgical procedures with associated morbidity. Precision approach robotic surgery leads to organ preservation. a multidisciplinary management improve patient outcomes. This study evaluates perioperative outcomes bowel undergoing planning and surgery. Methods Consecutive cases (January 2021–December 2022) were evaluated from prospectively maintained database in national accredited centre. Patients...