Aim . Animal and human study evidence supports the hypothesis that flaxseed lignan complex (FLC) at a dose of 600 mg secoisolariciresinol diglucoside (SDG)/day for three months would combat hyperglycaemia, dyslipidemia, blood pressure, central obesity, prothrombotic state, inflammation, low density lipoprotein (LDL) oxidation. Methods Sixteen type 2 diabetic patients completed this double-blind, randomised crossover placebo-controlled study. A univariate repeated measures analysis covariance...

A growing body of evidence confirms abnormal fatty acid (FAs) metabolism in the pathophysiology schizophrenia. Omega-3 polyunsaturated acids (PUFAs) are endogenous ligands G protein-coupled receptors, which have anti-inflammatory properties and a therapeutic target many diseases. No clinical studies concerned with role GPR120 signaling pathway The aim study was to determine differences PUFA nutritional status between patients schizophrenia (SZ group) healthy individuals (HC group). included...

Background: Infections and inflammation of the lower limb skin, soft tissues, vessels are more common than in other body regions. The aim was to determine whether cryptic bacteria dwelling deep tissues cause. Methods: We performed bacteriologic studies specimens harvested from arteries amputated ischemic legs, leg varices, tissue fluid/lymph lymphatics lymphedema. Results: Calf contained isolates 61% femoral 36%, whereas normal cadaveric organ donors' 11%. Bacterial deoxyribonucleic acid...

Schizophrenia has been considered a disorder linked with faulty lipid homeostasis, and the proposed tool for assessment of these disruptions is niacin skin flush test. The aims study were: 1. Create new to analyze results test more precisely objectively. 2. Verify utility self-created differentiating between schizophrenia (SZ; n = 56), bipolar (BD; 29) healthy control (HC; 45) individuals. developed method, based on Skin Reaction Measurement Computer System (SKINREMS), allows one evaluate...

ABSTRACT Wound healing should not be considered as a process limited only to the damaged tissues. It is always accompanied by an intensive local immune response and in advanced stages, systemic lymphatic (immune) structure. In this review we present evidence from our own studies well pertinent literature on role of skin subcutaneous tissue lymphatics at wound site transport antigens along with collecting afferent lymph nodes. We also speculate nodes raising cohorts bacterial antigen-specific...

Abstract Objective. The study is the second part of literature review on hyponatremia in patients with diagnosed mental disorders. This article focuses psychogenic polydipsia as, along SIADH, one two most common causes mentioned group patients. Method: was based searching Medline, Google Scholar and Ebsco databases Polish English by entering following phrases: polydipsia, psychosis – intermittent syndrome, water intoxication. Discussion: Psychogenic occurs up to 25% treated for It frequently...

Cel Pomimo burzliwego rozwoju badań nad zaburzeniami poznania społecznego w schizofrenii nadal trwają poszukiwania szerszych modeli konceptualnych, tym uwzględniających teorie sieciowe, wyjaśniających obserwowane zaburzenia. Celem naszej pracy była ocena struktury procesów na tle grupy porównawczej osób zdrowych psychicznie. Metoda Materiał: Badaniami objęto grupę 55 osób: 30 pacjentów z rozpoznaniem paranoidalnej wg DSM-IV okresie remisji oraz 25 tworzących kontrolną, dobraną pod kątem...

Ischaemia of the lower limbs is frequently followed by inflammation and, in advanced cases, necrosis peripheral tissues. Whether this caused arterial hypoperfusion only or presence bacteria walI as well remains unclear. The aim study was to prove and source specimens evaluate their chemotactic properties resulting formation periarterial cellular infiltrates.Bacterial culture testing for 16sRNA were performed fragments popliteal artery harvested from amputated limbs. Carotid plaques served...

Abstract Introduction. Hyponatremia is an important part of psychiatric practice. In order to analyze its causes and symptoms, the literature on hyponatremia in patients has been reviewed. The work divided into two separate manuscripts. first one authors discuss syndrome inappropriate antidiuretic hormone secretion (SIADH) occurring with use psychotropic drugs (antidepressants, antipsychotics, normotimics), while second paper discusses research psychogenic polydipsia. treated wards include:...

Abstract College Algebra is a gateway course for STEM majors with large enrollment and low passing rates. We analyze the factors which contribute to student success in courses at an urban community college. Characteristics grades of over twenty thousand students who were enrolled between years 2017 2022 have been analyzed. Among students' characteristics being studied are gender, ethnicity, age, first-generation college status, placement exam scores, grade point averages (GPA), whether they...

We documented previously the presence of bacterial flora in vascular bundles, lymphatics, and lymph nodes ischemic lower limbs amputated because multifocal atheromatic changes that made them unsuitable for reconstructive surgery discussed their potential role tissue destruction. The question arose why strains inhabiting limb skin considered to be saprophytes become pathogenic once they colonize deep tissues. Bacterial pathogenicity is evoked by activation multiple virulence factors encoded...

Abstract Ω-3 unsaturated fatty acids are compounds belonging to the group of essential (EFAs). The history discovery EFAs dates back 1930s twentieth century, however, growing interest in ω-3 context mental health has been observed since year 2000. In view their multidirectional action, these a promising form adjunctive therapy many illnesses, including psychiatric disorders. present article aims review literature on clinical applicability treating schizophrenia. We results preclinical...

Introduction: Currently, there are no fully reliable biomarkers to identify individuals suffering from depression, and conventional antidepressant treatment has its limitations. The potential influence of acetyl-L-carnitine (LAC) on the mental disorders, including depressive was noted already in 1980s.Goal method: literature role LAC particular reviewed using Google Scholar Pub Med databases. Two lines research were considered: 1the therapy various disorders and2the depression...

Abstract Introduction: The experience of trauma and stress in childhood early adulthood can lead not only to immediate physical psychological symptoms but also long-term effects observed later life. Aim method: objective the following study was search for correlation between occurrence its outcome, that is alcohol dependence, review studies concerning presence certain personality traits patients with such prognostic factors treatment. literature Google Scholar database reviewed using...

Background: Systemic lupus erythematosus (SLE) is an autoimmune disease that leads to a chronic inflammatory process in tissues and organs. The neuropsychiatric systemic (NPSLE) set of symptoms derive from the central peripheral nervous system are observed course SLE. Case Report Final Diagnostic Therapeutic Results: A diagnostic therapeutic patient with signs SLE bipolar disorder (BD) has been described. Bipolar diagnosed as primary while comorbid disease. Discussion: Common immunological...