A5052723928- Essential Oils and Antimicrobial Activity
- Plant Pathogens and Fungal Diseases
- Antifungal resistance and susceptibility
- Natural product bioactivities and synthesis
Universidade Federal do Rio de Janeiro
2016-2017
The aim of this study was to evaluate the activity EO and its major components Ocimum basilicum var. Maria Bonita, a genetically improved cultivar, against fluconazole sensitive resistant strains Candida albicans Cryptococcus neoformans. Geraniol presented better results than EO, with low MIC (76 μg/mL C. neoformans 152 both strains). combination linalool, or geraniol enhanced their antifungal activity, especially strain (MIC reduced 156, 197, 38 μg/mL, resp.). ergosterol assay showed that...
Ocimum basilicum L. (Lamiaceae) has been used in folk medicine to treat headaches, kidney disorders, and intestinal worms.This study evaluates the anti-cryptococcal activity of ethanol crude extract hexane fraction obtained from O. var. Maria Bonita leaves.The MIC values for Cryptococcus sp. were according Clinical Laboratory Standards Institute a range 0.3-2500 μg/mL. The checkerboard assay evaluated association substances tested (in 0.099-2500 μg/mL) with amphotericin B essential oil 48 h....