Jae Hak Sohn

ORCID: 0000-0001-8026-963X
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About
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Research Areas
  • Protein Hydrolysis and Bioactive Peptides
  • Microbial Natural Products and Biosynthesis
  • Marine Sponges and Natural Products
  • Meat and Animal Product Quality
  • Aquaculture Nutrition and Growth
  • Fungal Biology and Applications
  • Seaweed-derived Bioactive Compounds
  • Microbial Community Ecology and Physiology
  • Protein Tyrosine Phosphatases
  • Food Quality and Safety Studies
  • Bioactive Compounds and Antitumor Agents
  • Lichen and fungal ecology
  • Food Industry and Aquatic Biology
  • Genomics and Phylogenetic Studies
  • Microbial Metabolism and Applications
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Natural product bioactivities and synthesis
  • Probiotics and Fermented Foods
  • Plant Pathogens and Fungal Diseases
  • Biochemical effects in animals
  • Gastrointestinal motility and disorders
  • Echinoderm biology and ecology
  • Nutrition, Health and Food Behavior
  • Bryophyte Studies and Records
  • Insect Utilization and Effects

Silla University
2016-2025

Wonkwang University
2013-2015

Korea Research Institute of Bioscience and Biotechnology
1999-2009

Korea Polar Research Institute
2008

Pukyong National University
2008

Korea Institute of Ocean Science and Technology
1998-2004

A Gram-negative, yellow-pigmented, halophilic bacterial strain US6-1 T , which degrades high-molecular-mass polycyclic aromatic hydrocarbons of two to five rings, was isolated from muddy sediment Ulsan Bay, Republic Korea. The 16S rRNA gene the isolate showed high sequence similarity Novosphingobium subarcticum (96·23 %) and Sphingopyxis alaskensis (96·18 %); however, formed a distinct phyletic line within genus . DNA–DNA relatedness between closest N. revealed that independent this species....

10.1099/ijs.0.02945-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2004-09-01

Inflammation has always been considered a trigger or consequence of neurodegenerative diseases, and the inhibition inflammation in central nervous system can effectively protect nerve cells. Several studies have indicated that various natural products inhibit neuroinflammation. Among these, Antarctic fungal metabolites pharmacological activities developmental value. Therefore, this study aimed to evaluate anti-neuroinflammatory activity an fungus belonging Aspergillus (strain SF-7367)....

10.3390/molecules30020294 article EN cc-by Molecules 2025-01-13

A bacterium (named OT-1 T ) that showed algicidal activity was isolated from sea water of Masan Bay, Korea, during an outbreak red tide. Phylogenetic analysis based on 16S rDNA sequences the isolate formed a distinct phyletic lineage within family Flavobacteriaceae Cytophaga – Flavobacterium Bacteroides group. No species with validly published name ⩾93 % rRNA gene sequence similarity to strain . The had major amounts iso-branched and 3-hydroxy fatty acids menaquinone 6 DNA G+C content 34...

10.1099/ijs.0.02689-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2004-05-01

Constipation is a common problem in males and females. The aim of the present study was to evaluate laxative effects fermented rice extract (FRe) on rats with loperamide‑induced constipation. FRe (100, 200 300 mg/kg) administered orally once per day for six days following 1 h loperamide treatment. were compared those sodium picosulfate (S. picosulfate). Following induction constipation rats, marked decrease observed fecal pellet number water content discharged over 24 h, surface mucus...

10.3892/etm.2014.2030 article EN Experimental and Therapeutic Medicine 2014-10-17

Summary Globally, Pacific oysters ( Crassostrea gigas ) have a high market demand owing to their increased nutritional value. can be dietary source meet the daily needs. Several studies evaluated value and bioactivity of C. . However, review examining has not been previously performed. This study aimed evaluating bioactivities components using Preferred Reporting Items for Systematic Reviews Meta‐Analyses guidelines. The online databases Web Science, ScienceDirect, MEDLINE PubMed were...

10.1111/ijfs.15939 article EN International Journal of Food Science & Technology 2022-06-27

Salting is one of the oldest food preservation techniques. However, salt also source living halophilic microorganisms that may affect human health. In order to determine microbial communities commercial salts, an investigation were done using amplicon sequencing approach in four salts: Ethiopian Afdera (EAS), rock (ERS), Korean Jangpan (KJS), and Topan (KTS). Using domain-specific primers, a region 16S rRNA gene was amplified sequenced Roche 454 instrument. The results indicated these...

10.3389/fmicb.2017.00799 article EN cc-by Frontiers in Microbiology 2017-05-10

Alternaramide (1), a cyclic pentadepsipeptide, has been isolated from an EtOAc extract of the marine-derived fungus Alternaria sp. SF-5016 by various chromatographic methods. The structure 1 was mainly determined analysis NMR spectroscopic data, along with chemical methods such as Marfey's and Mosher's (1) showed weak antibiotic activity against Bacillus subtilis Staphylococcus aureus.

10.1021/np900464p article EN Journal of Natural Products 2009-10-08

Chemical study on the extract of a marine-derived fungal strain Penicillium sp. SF-5859 yielded new curvularin derivative (1), along with eight known curvularin-type polyketides (2-9). The structures these metabolites (1-9) were established by comprehensive spectroscopic analyses, including 1D and 2D nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry (MS). In vitro anti-inflammatory effects evaluated in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages. Among...

10.3390/md15090282 article EN cc-by Marine Drugs 2017-09-02

Chemical investigation of the EtOAc extracts marine-derived fungal isolates Aspergillus sp. SF-5974 and SF-5976 yielded a new dihydroisocoumarin derivative (1) 12 known metabolites. The structures isolated metabolites were established by extensive spectroscopic analyses, including 1D 2D NMR spectra MS data. Among metabolites, absolute configuration 5′-hydroxyasperentin (6) was determined single-crystal X-ray diffraction analysis. in vitro antineuroinflammatory effects also evaluated...

10.1021/acs.jnatprod.5b00614 article EN Journal of Natural Products 2015-12-14
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