- Trauma and Emergency Care Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Trauma Management and Diagnosis
- Hip and Femur Fractures
- Cardiac Arrest and Resuscitation
- Frailty in Older Adults
- Emergency and Acute Care Studies
- Airway Management and Intubation Techniques
- Abdominal Trauma and Injuries
- Sepsis Diagnosis and Treatment
- Appendicitis Diagnosis and Management
- Restraint-Related Deaths
- Intestinal Malrotation and Obstruction Disorders
- Bone Tissue Engineering Materials
- Aortic Disease and Treatment Approaches
- Bariatric Surgery and Outcomes
- Vasculitis and related conditions
- Pancreatitis Pathology and Treatment
- Congenital Diaphragmatic Hernia Studies
- Esophageal and GI Pathology
- Sinusitis and nasal conditions
- COVID-19 Clinical Research Studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Enhanced Recovery After Surgery
- Geriatric Care and Nursing Homes
Massachusetts General Hospital
2020-2025
Twitter (United States)
2025
Harvard University
2020-2025
American University of Beirut Medical Center
2022-2025
Bridge University
2024
American University of Beirut
2022-2023
Purpose Coronavirus disease-2019 (COVID-19) is associated with a wide spectrum of clinical symptoms including acute respiratory failure. Biomarkers that can predict outcomes in patients COVID-19 assist patient management. The aim this study to evaluate whether procalcitonin (PCT) outcome and bacterial superinfection infected severe syndrome coronavirus-2 (SARS-CoV-2). Methods Adult diagnosed SARS-CoV-2 by nasopharyngeal PCR who were admitted tertiary care center Boston, MA infection between...
Mirzayan, Raffy MD; Panossian, Vahé Avedian, Raffi BS; Forrester, Deborah M. Menendez, Lawrence R. MD
Pulmonary artery catheters use remain invaluable in continuous invasive hemodynamic monitoring for patients with severe cardiopulmonary dysfunction and those undergoing major cardiac surgeries. It detects guides treatment decisions. Its utilization has declined due to common complications associated its insertion. This article highlights a rare, rather an important complication of pulmonary catheter knotting reviews techniques management. Prompt recognition this rare by the clinicians allow...
Objective: To examine the impact of hospital volume on mortality and healthcare utilization in patients admitted with necrotizing pancreatitis (NP). Background: Over 20% acute develop NP, which has been associated higher rates procedural intervention, morbidity, mortality. Methods: Adult NP were identified 2016-2019 Nationwide Readmissions Database 2016-2019. Hospital cutoffs defined by tertiles total admissions per year (low-volume [<9 admissions/year]; medium-volume [9-25 high-volume...
Background: The identification of the optimal management for blunt splenic trauma—angioembolization (AE), splenectomy, or observation—remains a challenge. This study applies Optimal Policy Trees (OPT), an artificial intelligence (AI) model, to prescribe appropriate and improve in-hospital mortality. Methods: OPTs were trained on patients with injuries in ACS-TQIP 2013–2019 one three interventions: angioembolization observation. Prescriptive trees derived two separate patient cohorts: those...
BACKGROUND Previous studies have shown that patients with rib fractures experience long-term functional limitations. However, the specific predictors of these worse limitations remain under-characterized. METHODS We conducted a prospective cohort study including ≥18 years an injury severity score ≥9 and isolated chest injury. Patients included had ≥1 fracture were admitted between July 2015 May 2019 at one three Level I trauma centers present in our region. performed stepwise regression...
<h3>Background</h3> ANCA-associated vasculitis (AAV) carries excessive morbidity and mortality owing to the delay in diagnosis limited prognostication. Identifying clinically useful biomarkers of disease activity that facilitate accurate prognostication would help personalize management decisions. Biomarkers used day-to-day practice include PR3- or MPO-ANCA, CRP, ESR, but these poorly predict future activity. Few studies have examined a number circulating proteins as biomarkers, including...
Mid-regional proadrenomedullin (MR-proADM) is a biomarker released following endothelial damage. Studies have shown correlation in predicting coronavirus disease 2019 (COVID-19) outcomes with MR-proADM levels. Our study aimed to investigate baseline as predictor of wider range clinical varying severity patients admitted COVID-19, and compare other biomarkers. Data from the Boston Area COVID-19 Consortium (BACC) Bay Tocilizumab Trial was used this study. Patients determinations, not intensive...