A5032794247- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Pelvic floor disorders treatments
- Andrographolide Research and Applications
- Animal Genetics and Reproduction
- Phytochemicals and Medicinal Plants
- Gastric Cancer Management and Outcomes
- Cancer Genomics and Diagnostics
- Cancer, Lipids, and Metabolism
- Folate and B Vitamins Research
- Esophageal Cancer Research and Treatment
- Reproductive Health and Technologies
- Retinoids in leukemia and cellular processes
- Urinary Tract Infections Management
- Acute Myeloid Leukemia Research
- Intraperitoneal and Appendiceal Malignancies
- Ovarian cancer diagnosis and treatment
- Lung Cancer Treatments and Mutations
The University of Texas MD Anderson Cancer Center
2005-2025
National Health and Family Planning Commission
2018-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Academy of Medical Sciences
2024
This study aims to provide reference data for sperm morphology in a healthy, fertile male population providing foundation future studies on infertility assessment and selection assisted reproductive technologies. The included 21 healthy participants, all of whom had partners who conceived within the past 12 months. Sperm samples were collected according WHO guidelines stained using Papanicolaou method. parameters, including head length, width, area, perimeter, ellipticity, acrosome measured...
Goal: To assess the feasibility, reliability, and limitations of using Whole Genome Bisulfite Sequencing (WGBS) for detecting somatic copy number variation (SCNV) tumor-specific allelic imbalance (AI). Background: In cancer genomics, use WGBS SCNV AI detection enables simultaneous analysis genetic variations methylation landscapes, potentially providing insights into interplay between alterations DNA in tumorigenesis. However, data is inherently noisier compared to whole-genome sequencing...
This study aimed to identify the altered pathways and genes associated with freezing damage in human sperm during cryopreservation by multiomics analysis.
Background Recent advances in microbiome research have revealed the presence of diverse microbial communities human tissues previously thought to be sterile. The present study delves into emerging field seminal plasma microbiomics, examining relationship between semen microbes and parameters post-freezing tolerance. Methods involved a cohort healthy fertility males genome analysis using 16S rRNA characterize diversity plasma. Microbial identified unique amplicon sequence variants (ASVs)...
Background: Recent advances in microbiome research have revealed the presence of diverse microbial communities human tissues previously thought to be sterile. The present study delves into emerging field semen microbiomics, examining relationship between microbes and parameters post-freezing tolerance. Methods: involved a cohort healthy fertility males genome analysis using 16S rRNA characterize diversity semen. Microbial identified unique primer sequence variants (ASVs) genera dominant...
4046 Background: The survival of patients with local-regional adenocarcinoma the esophagus or esophagogastric junction (EGJ) treated preoperative chemoradiation is better in pathologic complete response than those residual tumor. Residual tumor, including presence lymph node (LN) metastasis, associated poor outcome. However, prognostic significance number metastases remains unclear. Methods: We studied 187 consecutive followed by esophagectomy. Post-therapy depth tumor invasion (T stage) and...