A5071242188- Congenital Heart Disease Studies
- Prenatal Screening and Diagnostics
- Ultrasound in Clinical Applications
- Pregnancy and preeclampsia studies
- Assisted Reproductive Technology and Twin Pregnancy
- Birth, Development, and Health
- Pediatric Urology and Nephrology Studies
- Fetal and Pediatric Neurological Disorders
- Tracheal and airway disorders
- Vascular anomalies and interventions
- Cardiac Structural Anomalies and Repair
- Innovations in Medical Education
- Neonatal Respiratory Health Research
- Mechanical Circulatory Support Devices
- Medical Education and Admissions
- Congenital Diaphragmatic Hernia Studies
- Medical and Health Sciences Research
- Urinary Tract Infections Management
- Cardiovascular Issues in Pregnancy
- Renal and related cancers
- Coronary Artery Anomalies
- Teratomas and Epidermoid Cysts
- Abdominal Trauma and Injuries
- Autopsy Techniques and Outcomes
- Clinical Reasoning and Diagnostic Skills
University Hospital Bonn
2017-2025
University of Bonn
2020-2023
Klinik für Frauenheilkunde
2023
Charité - Universitätsmedizin Berlin
2009
Heinrich Heine University Düsseldorf
2006-2007
Choosing a medical specialty is pivotal moment in physician's career, shaped by personal interests, clinical experiences, and professional interactions. Obstetrics gynecology (OB-GYN) offers unique blend of surgical care focused on women's health. Given the growing demand for OB-GYN specialists, understanding factors that influence students' decisions essential workforce planning. This study compares influencing first-year final-year students at University Bonn their decision to pursue...
Abstract Introduction The emergence of handheld ultrasound devices capable connecting to cell phones or tablets heralds a significant advancement in medical technology, particularly within the field obstetrics. These offer promise immediate bedside examinations, potentially revolutionizing patient care by enabling fetal assessments diverse settings. Material and Methods This prospective study aimed validate reliability non‐piezo, chip‐based clinical obstetric practice. Conducted university...
Rac proteins of the Rho-like GTPase family, including ubiquitous Rac1, hematopoiesis-specific Rac2, and least-characterized Rac3 play a major role in oncogenic transformation, tumor invasion metastasis. However, prognostic relevance expression human tumors has not been investigated yet. In present study, protein was analyzed benign secretory epithelium, high-grade prostatic intraepithelium neoplasia (HG-PIN), prostate carcinomas 60 R0-resected radical prostatectomy specimens by...
The Rac-specific guanine nucleotide exchange factor, Tiam1, plays a major role in oncogenicity, tumour invasion and metastasis but its usefulness as prognostic marker human cancer has not been tested yet. In the present study, Tiam1 expression was analysed benign secretory epithelium, pre-neoplastic high-grade prostatic intraepithelium neoplasia (HG-PIN) prostate carcinomas of 60 R0-resected radical prostatectomy specimens by semiquantitative immunohistochemistry. proved significantly...
Gastric adenocarcinomas are associated with a poor prognosis due to the fact that tumor has often metastasized by time of diagnosis and prognostic markers urgently needed tailor treatment. We examined expression mitotic spindle checkpoint protein BUB1 (budding uninhibited benzimidazoles 1) Ki-67 immunohistochemistry in 218 patients primary gastric adenocarcinomas. Tumors low frequency were larger size (pT) (p < 0.001), higher incidence lymph node metastases (pN) = 0.027), distant (pM) 0.006)...
Abstract Objective Restrictive foramen ovale (FO) in dextro-transposition of the great arteries (d-TGA) with intact ventricular septum may lead to severe life-threatening hypoxia within first hours life, making urgent balloon atrial septostomy (BAS) inevitable. Reliable prenatal prediction restrictive FO is crucial these cases. However, current echocardiographic markers show low predictive value, and often fails fatal consequences for a subset newborns. In this study, we described our...
Objectives: Different retrospective growth charts for twin pregnancies debates whether is similar to singletons. Recently, the fetal medicine foundation (FMF) published a chart that indicated twins and singleton if only term delivery of both without major malformation are included. A national Denish confirmed these finding. We constructed prospective estimated weight (EFW) throughout pregnancy monochorionic diamniotic (MCDA) dichorionic (DC) using multi-center, multi-national cohort. Study...
Abstract Introduction The technical development of ultrasound devices based on silicon chips has revolutionized examinations, leading to the implementation these portable handheld (PUD) in different medical fields. However, training is necessary assure appropriate use and ensure valid results. While programs for conventional standard (SUD) have been described, no program developed thus far. Methods A obstetric examination was modified through addition an extra module focusing PUDs. After...
Abstract This study aimed to evaluate the effectiveness of a prenatal ultrasound course for medical students, focusing on enhancing competencies in fetal sonography through integration theoretical knowledge and hands-on practice. was longitudinal conducted over winter semester 2023/24. Study took place education setting, with practical sessions clinical environment instruction. Twenty students participated course. The taught by expert faculty included training live models real-life...
To compare the detection rate for trisomy 21 of universal cell free DNA (cfDNA) screening with contingent screening.Retrospective study at 3 German centers. The included euploid and pregnancies where cfDNA first trimester (FT) assessment was carried out. FT risk computed based on combined stratified into following classes: high >1:10, intermediate 1:11 - 2,500, low <1:2,500. For screening, test results were examined. model, result taken account in case an risk. Different strategies combining...
Abstract To assess the spectrum of different etiologies, intrauterine course, outcome and possible prognostic markers in prenatally detected fetal growth restriction (FGR) combined with polyhydramnios. Retrospective study 153 cases FGR Polyhydramnios diagnosed by prenatal ultrasound over a period 17 years. Charts were reviewed for findings, postnatal outcome. All categorized into etiological groups examined differences. Five identified: chromosomal anomalies (n = 64, 41.8%), complex...
Objective: To assess the course and outcome of fetal aortic valvuloplasty (FAV) in fetuses with severe stenosis (SAS) a single center. Methods: All prenatal diagnosis SAS subsequent FAV were retrospectively collected one tertiary center for medicine over period 10 years. In study, considered suitable presence markedly elevated left ventricular pressures (maximum velocity mitral regurgitation (MR Vmax) >250 cm/s and/or maximum (AS cm/s), retrograde flow transverse arch length Z-score >−1....
Objective structured clinical examination (OSCE) is a well-known assessment method to evaluate skills and competence in healthcare. Following the recently reformed National Competence-Based Catalog of Learning Objectives Medicine, implementation this training program for medical students now obligatory Germany. This major change requires reorganization not only programs but also themselves way they learn. We performed poll evaluating students’ opinions regarding these changes OSCE with new...
: Truncus arteriosus communis (TAC) is a rare congenital heart defect characterized by single arterial trunk that supplies systemic, pulmonary, and coronary circulations. This defect, constituting approximately 1-4% of diseases, poses significant challenges in prenatal diagnosis, management, postnatal outcomes.
Abstract Objective To investigate the uptake of different components first trimester screening (FTS) and impact on invasive diagnostic testing (IPT) since introduction non-invasive prenatal (NIPT) at a level III center. Methods Retrospective data analysis was conducted for singleton pregnancies that presented FTS between 01/2019–12/2019 (group 1, n = 990). Patients were categorized into three risk groups: low trisomy 21 (< 1 : 1000), intermediate (1 101–1 1000) high (≥ 100). Uptake NIPT...
Prenatal detection of complex giant hepatic arteriovenous malformation requires an examination the affected fetal hemodynamic situation with emphasis on arterial supply pattern. Early pediatric surgeon presentation is needed, as timely surgical intervention appears to be essential.
Zielsetzung: Die zunehmende Bedeutung von Ultraschalluntersuchungen in der Gynäkologie und Geburtshilfe hebt die Notwendigkeit einer qualitativ hochwertigen Ausbildung hervor. Diese Recherche zielt darauf ab, eine systematische Übersicht über Struktur Qualität Ultraschallausbildung im Fachgebiet zu erstellen mögliche Verbesserungen identifizieren.
to assess the course and outcome of fetuses affected by primary cardiomyopathy (CM). Retrospective study 21 cases with prenatal diagnosis a CM in one tertiary center over period 20 years. Charts were reviewed for echocardiographic findings, pregnancy outcome, postnatal course. The utility evaluation was discussed. mean gestational age (GA) at 26.7 (±5.1) weeks. A total 33.3% (7/21) had associated anomalies. Genetic etiology confirmed 50.0% (10/20, case lost follow up). overall survival rate...