A5022500366- COVID-19 and healthcare impacts
- Disaster Response and Management
- Global Cancer Incidence and Screening
- COVID-19 epidemiological studies
- Vaccine Coverage and Hesitancy
- Health Systems, Economic Evaluations, Quality of Life
- Artificial Intelligence in Healthcare and Education
- SARS-CoV-2 and COVID-19 Research
- Palliative Care and End-of-Life Issues
- Pharmaceutical Economics and Policy
- Cervical Cancer and HPV Research
- Advances in Oncology and Radiotherapy
- Radiation Dose and Imaging
- Healthcare Policy and Management
- Health and Conflict Studies
- COVID-19 and Mental Health
- Hepatitis B Virus Studies
- Pharmaceutical industry and healthcare
- Economic and Financial Impacts of Cancer
- RNA Interference and Gene Delivery
- Clinical practice guidelines implementation
- Viral Infections and Outbreaks Research
- Biomedical Ethics and Regulation
- Zoonotic diseases and public health
- Risk Perception and Management
Hokkaido University
2021-2025
Jyoban Hospital
2022-2025
Orange (Poland)
2025
Aomori University of Health and Welfare
2023-2024
Keio University
2023-2024
Mimasaka University
2024
Aomori University
2023-2024
Olympus (Japan)
2023-2024
Weatherford College
2024
Sapporo University
2024
To develop an effective strategy to prevent neointima formation after angioplasty injury, we have identified cell-cycle regulatory proteins as targets for inhibition by using antisense oligonucleotides (ODNs). We utilized intraluminal molecular delivery method that employs the protein coat of a Sendai virus complexed with liposomes enhances markedly efficiency ODNs uptake. First, examined effect cdc2 kinase and proliferating-cell nuclear antigen (PCNA) in vitro. Cotransfection PCNA inhibited...
Purpose The purpose of this study was to evaluate the changes in capabilities between Generative Pre-trained Transformer (GPT)-3.5 and GPT-4 versions large-scale language model ChatGPT within a Japanese medical context. Methods involved 3.5 4 responding questions from 112th National Nursing Examination (JNNE). comprised three analyses: correct answer rate score calculations, comparisons GPT-3.5 GPT-4, rates for conversation questions. Results responded 237 out 238 JNNE. While achieved an...
Japan's conditional/time‐limited early approval program, initiated in 2014, aimed to advance regenerative medicine by expediting market access. However, the withdrawal of autologous skeletal myoblast sheets (Heartsheet) due ineffectiveness raises concerns about balance between rapid and scientific integrity. While program seeks boost innovation, it risks endorsing costly, unclear treatments under national health care. This case highlights need refine regulatory approaches, ensuring clinical...
Rigorous and transparent management strategies for conflicts of interest clinical practice guidelines with the best available evidence are necessary development nephrology guidelines. However, there was no study assessing financial nonfinancial interest, quality underlying Japanese CKD, conflict policies guideline development.
Objective To assess financial conflicts of interest (COI) and nonfinancial COI among psoriatic arthritis (PsA) clinical practice guideline (CPG) authors in Japan the US, to evaluate quality evidence strength recommendations PsA CPGs. Methods We performed a retrospective analysis using payment data from major Japanese pharmaceutical companies US Open Payments Database 2016 2018. All CPGs issued by Dermatological Association (JDA) American College Rheumatology (ACR) were included. Results Of...
ChatGPT is gaining widespread acceptance for its ability to generate natural language sentences in response various inputs and expected become a supplementary tool diagnosing determining treatment policies clinical settings. was used evaluate perform inference accuracy answering questions on the 117th Japanese National Medical Licensing Examination held February 2023. The exam were manually inputted into ChatGPT's window, of responses determined based answers provided by preparatory school....
Cervical cancer is prevalent among women, with a reported 604,127 cases in 2020 worldwide. The incidence of cervical has been mitigated most high-income countries by promoting the human papilloma virus (HPV) vaccine. However, Japan, still leading cause mortality and women aged between 15 39. This can be attributed to 7-year suspension HPV vaccination recommendations Japanese government. A decline coverage followed this suspension, caused small number adverse events, resulting steep from over...
In recent years, Japan has faced a significant demographic crisis, which was further exacerbated by the coronavirus disease 2019 (COVID-19) pandemic. By 2022, country experienced 1.5% decrease in population, is contrast to other G7 nations, and had highest rate of excess mortality among Organization for Economic Co-operation Development (OECD) countries. This crisis mainly attributed aging with Japan's reaching 29.9%, its peer The Japanese government, led Prime Minister Fumio Kishida,...
Before the COVID-19 vaccine became available, many Japanese people were undecided about whether or not to receive them. Their decisions keys achieving herd immunity. The impact of type information source on uptake decision-making process remains unclear. We aimed investigate association between usage and subsequent status among those who have yet decide vaccines from non-prioritized for vaccination.Prospective cohort online self-administered surveys conducted in February 2021 (T1), before...
Artificial intelligence (AI), particularly ChatGPT, developed by OpenAI (San Francisco, CA, USA), is making significant strides in the medical field. In a simulated case study, 66-year-old Japanese female patient's dialogue with physician was transcribed and inputted into ChatGPT to assess its efficacy drafting records, formulating differential diagnoses, establishing treatment plans. The results showed high similarity between summaries generated those of attending physician. This suggests...
Little is known about how crises might affect the long-term uptake of breast cancer screening programs. This study aimed to clarify trend program in Minamisoma City following 2011 Triple Disaster Fukushima, Japan (earthquake, tsunami, and nuclear disaster), evaluate factors associated with this uptake. retrospectively analyzed data from Basic Resident Registry Breast Cancer Screening Program Disaster. We calculated annual rate for women aged 40-74 years who were an even-numbered age at end...
Purpose This study aimed to evaluate the performance and acceptance of responses generated by ChatGPT-3.5 GPT-4 Japanese childcare-related questions assess their potential applicability limitations in childcare field, specifically focusing on accuracy, usefulness, empathy answers. Methods We evaluated answers GPT-3.5 for two types questions. ① For written examination Japan's worker national 2023's fiscal year, we calculated correct answer rates using official ② selected one question from...
Journal Article Corrected proof Japan's medical workforce crisis: Nagoya University's new policy significantly reducing physician compensation for education and research Get access Y Kaneda, Kaneda Conceptualization, Writing - original draft School of Medicine, Hokkaido University, Hokkaido, Japan Address correspondence to Y. Kita15, Nishi7, Kita-ku, Sapporo, 0608638, Japan. email: nature271828@gmail.com https://orcid.org/0000-0001-8302-9439 Search other works by this author on: Oxford...
There is limited information on whether the COVID-19 pandemic was associated with decreased breast cancer screening uptake and if vaccination an increase in uptake. Our study explored of Japan after assessed its association vaccination. We analyzed data from Society Internet Survey (JACSIS), a web-based prospective cohort survey, we included 6110 women without history who were aged 40 to 74 years that participated 2012 2022 surveys. examined regular before employed multivariable Poisson...
Large-scale disasters can severely impact breast cancer care, leading to treatment disruptions and delays. While empirical studies on these effects are limited, patient narratives provide valuable insights. This study explored continuity medical access among local patients affected by the 2011 triple disaster through qualitative research methods. The involved 21 diagnosed before disaster. After obtaining consent, semi-structured interviews ranging from 20 minutes an hour were conducted, data...
Premenstrual syndrome (PMS) is a common menstrual disorder that can significantly impact the physical, emotional, and social well-being of affected women. However, PMS remains neglected problem in Afghanistan, with limited data on its prevalence impact. This study aimed to determine more severe premenstrual dysphoric (PMDD) among female university students Kabul, Afghanistan. Researchers conducted cross-sectional from April October 2021 at four universities Kabul. They included total 310...
ABSTRACT Background Maintaining a high participation rate is crucial for effective colorectal cancer (CRC) screening. The COVID‐19 pandemic placed significant burden on healthcare facilities, which hindered CRC screening efforts. However, the effects of prolonged remain unclear. Methods We analyzed data from Japan and Society Internet Survey in September 2021 2022 to examine over past year. also evaluated association between status, future intentions, background characteristics, anxiety...