A5026120212- Pesticide Exposure and Toxicity
- Insect and Pesticide Research
- Pesticide and Herbicide Environmental Studies
- Environmental Toxicology and Ecotoxicology
- Analytical Chemistry and Sensors
- Insect Pest Control Strategies
- Quality and Safety in Healthcare
- Aquatic Ecosystems and Biodiversity
- Mosquito-borne diseases and control
- Pharmaceutical and Antibiotic Environmental Impacts
- bioluminescence and chemiluminescence research
- Electrochemical sensors and biosensors
- Air Quality and Health Impacts
- Occupational Health and Safety Research
- Wastewater Treatment and Nitrogen Removal
- Global Public Health Policies and Epidemiology
- Microbial Community Ecology and Physiology
- Zoonotic diseases and public health
- Animal Ecology and Behavior Studies
- Climate Change and Health Impacts
- Electrochemical Analysis and Applications
- Water Quality Monitoring Technologies
- RNA Interference and Gene Delivery
- Heavy Metal Exposure and Toxicity
- Open Source Software Innovations
Swiss Federal Institute of Aquatic Science and Technology
2018-2022
ETH Zurich
2018-2021
Swiss Tropical and Public Health Institute
2019
University of Basel
2019
Babraham Institute
2014
Multiple anthropogenic drivers are changing ecosystems globally, with a disproportionate and intensifying impact on freshwater habitats. A major of urbanization inputs from wastewater treatment plants (WWTPs). Initially designed to reduce eutrophication improve water quality, WWTPs increasingly release multitude micropollutants (MPs; i.e., synthetic chemicals) microbes (including antibiotic-resistant bacteria) receiving environments. This pollution may have pervasive impacts biodiversity...
Multiple epidemiological studies have shown that exposure to single pesticide active ingredients or chemical groups is associated with adverse neurobehavioral outcomes in farmers. In agriculture, multiple the rule, rather than exception. Therefore, occupational on effects of pesticides should account for potential co-exposure confounding. We conducted a cross-sectional study 288 Ugandan smallholder farmers between September and December 2017. collected data self-reported use products during...
A single microRNA (miRNA) can regulate the expression of many genes, though level repression imparted on any given target is generally low. How then selective pressure for a miRNA/target interaction maintained across long evolutionary distances? We addressed this problem by disrupting in vivo between miR-155 and PU.1 mice. Remarkably, proved to be key promoting optimal T cell–dependent B cell responses, previously unrecognized role PU.1. Mechanistically, inhibits expression, leading Pax5...
Pesticides are used globally in agriculture and pose a threat to the health of farmers, communities, environment. Smallholder farmers low- middle-income countries have generally low socio-economic status educational level. Consequently, they particularly vulnerable negative impacts pesticides on their health, yields, or land. In Knowledge, Attitude, Practices study, we compared pest management practices between market-oriented farming system Zarcero County, Costa Rica, subsistence-based...
Pesticide use is increasing in low- and middle-income countries (LMICs) including Costa Rica. This increase poses health risks to farm owners, workers, communities living near agricultural farms.We aimed examine the effects associated with occupational pesticide exposure owners workers from conventional organic smallholder farms Rica.We conducted a cross-sectional study involving 300 horticultural Zarcero County, During baseline visit, we administered structured, tablet-based questionnaire...
Conventional pesticides are associated with numerous human and environmental health risks. Nevertheless, an increasing number of smallholder farmers in low- middle-income countries using conventional pesticides. Adopting safer pest management requires to obtain new information. However, little is known how develop information need, seek, use related information, whether this process differs for organic strategies. In qualitative study, we investigated pest-related behavior depth, from...
Poorly educated smallholder farmers in low-income countries are highly exposed to pesticides. This can result adverse mental health issues, of which sleep problems might be an underlying indicator. We aim examine the association between and pesticide exposure among Uganda.A cross-sectional survey with 253 was conducted October December 2019. Sleep were assessed during week before visit using Medical Outcomes Study Scale (MOS-SS). Exposure pesticides as application days any use 2,4-D,...
Abstract Background Pesticides can have negative effects on human and environmental health, especially when not handled as intended. In many countries, agro-input dealers sell pesticides to smallholder farmers are supposed provide recommendations application handling. This study investigates the role of in transmitting safety information from chemical manufacturers farmers, assesses their shops, what products they sell, how abide by laws best practices for preventing pesticide risk...
Objective Estimates of pesticide exposure among applicators from low- and middle-income countries (LMICs) are scarce, assessment methods sometimes costly or logistically unfeasible. We examined the variability in weeklong Costa Rica its predictors. Methods conducted a cross-sectional survey 221 organic, sustainable conventional farms 2016. administered structured questionnaires to assess application practices at two time points (4–6 weeks apart). adapted an existing algorithm fit context...
Introduction and aim Exposure to some insecticides may cause airway obstruction, but existing evidence is limited by cross-sectional designs inadequate confounder control. We investigated the relation between organophosphate carbamate pulmonary function in a prospective study accounting for important confounders. Methods In cohort of 364 smallholder farmers Uganda (69% women), participants underwent pre-bronchodilator spirometry at baseline (September/October 2018) two follow-up visits...
Pesticides are intensely used in the agricultural sector worldwide including smallholder farming. Poor pesticide use practices this agronomic setting well documented and may impair quality of water resources. However, empirical data on occurrence bodies tropical agriculture is scarce. Many available focusing apolar organochlorine compounds which globally banned. We address gap by studying a broad range more modern pesticides an watershed Uganda. During 2.5 months rainy season 2017, three...
Previous epidemiological studies have reported associations of pesticide exposure with poor cognitive function and behavioral problems. However, these findings relied primarily on neuropsychological assessments. Questions remain about the neurobiological effects exposure, specifically where in brain pesticides exert their whether compensatory mechanisms may masked pesticide-related that purely measures. We conducted a functional neuroimaging study 48 farmworkers from Zarcero County, Costa...
Studies suggest that acute pesticide poisonings (APP) may be linked with long-term neurological effects. To examine and psychological distress symptoms associated having experienced an APP, we conducted a cross-sectional study of 300 conventional organic smallholder farmers from Zarcero County, Costa Rica, May-August 2016. We collected self-reported data on sociodemographic characteristics, occupational history, exposure, APPs, (using the Brief Symptom Inventory (BSI)). Adjusted logistic...
Objectives The risk of diabetes mellitus may be elevated among persons exposed to some pesticides, including cholinesterase-inhibiting insecticides (organophosphates and carbamates). objective this study was investigate how acetylcholinesterase activity associated with mean blood glucose levels smallholder farmers in Uganda. Methods We conducted a short-term follow-up 364 Participants were examined three times from September 2018 February 2019. At each visit, we measured glycosylated...
Wicked problems exceed traditional sectoral and jurisdictional boundaries involve multiple actors as stakeholders, victims, culprits. inherently feature uncertainty knowledge gaps. Science plays a crucial role in generating evidence for solving these contributing to societal transformation. However, researchers may perceive study detached from practitioners' perceptions of the world. We use example smallholder pesticide management Uganda three types approach, framework borrowed...
Over the past three decades, Vietnamese Mekong Delta has experienced a significant increase in agricultural productivity, partly achieved through increased agrochemical use. To abate negative effects on human and environmental health, several national programs were launched to enhance safer pesticide This study aimed assess patterns relationships of official sustainable agriculture educational programs, safety knowledge, practices smallholder farmers Delta. A cross-sectional survey was...
Monitoring and maintaining the quality of water is important since it one most resources basis all life. However, current methods are stationary or obsolete. The IMOLA system able to measure vitality living cells online, marker free in real time through a multiparametric microsensor chip. In combination with green algae as signal transducers was elucidated how an emulsion oil affects algae. It shown that using Parachlorella kessleri biosensor unit suitable for mobile, online-detection...
<sec> <title>BACKGROUND</title> Pesticide use is increasing in low- and middle-income countries (LMICs) including Costa Rica. This increase poses health risks to farm owners, workers, communities living near agricultural farms. </sec> <title>OBJECTIVE</title> We aimed examine the effects associated with occupational pesticide exposure owners workers from conventional organic smallholder farms <title>METHODS</title> conducted a cross-sectional study involving 300 horticultural Zarcero County,...
Objective Evaluate the accuracy and precision of copd-6 mini-spirometer for FEV 1 in a rural Ugandan population. Methods In cross-sectional study, 171 smallholder farmers performed spirometry with copd-6, diagnostic-quality spirometer. Results discussion The underestimated at low flows overestimated high flows. Across all participants, device slightly by 0.04 [0.02; 0.06] L. Calibration data showed similar patterns. Conclusion could be considered as an affordable tool research on lung...