Daron Smith

ORCID: 0000-0001-8314-4795
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About
Contact & Profiles
Research Areas
  • Kidney Stones and Urolithiasis Treatments
  • Pediatric Urology and Nephrology Studies
  • Ureteral procedures and complications
  • Urological Disorders and Treatments
  • Reproductive Health and Technologies
  • Renal and Vascular Pathologies
  • Pelvic floor disorders treatments
  • Male Reproductive Health Studies
  • Appendicitis Diagnosis and Management
  • Urinary Tract Infections Management
  • RNA modifications and cancer
  • Cardiac, Anesthesia and Surgical Outcomes
  • Urinary Bladder and Prostate Research
  • RNA Research and Splicing
  • Paleopathology and ancient diseases
  • RNA and protein synthesis mechanisms
  • Virus-based gene therapy research
  • Sperm and Testicular Function
  • Traumatic Ocular and Foreign Body Injuries
  • Bladder and Urothelial Cancer Treatments
  • Sexual function and dysfunction studies
  • Prostate Cancer Diagnosis and Treatment
  • Renal cell carcinoma treatment
  • Laser Applications in Dentistry and Medicine
  • Intestinal and Peritoneal Adhesions

University College London
2016-2025

University College London Hospitals NHS Foundation Trust
2015-2025

University College Hospital
2015-2025

Endourological Society
2024-2025

Multiple Sclerosis Society
2024

University of California, San Francisco
2009-2024

George Mark Children's House
2024

University College Hospital at Westmoreland Street
2022-2024

British Association of Urological Surgeons
2022

Northern General Hospital
2019-2020

We sequenced two recombinant DNA clones constituting a single provirus of the milk-transmitted mouse mammary tumor virus characteristic BR6 mice. The complete is 9,901 base pairs long, flanked by 6 base-pair duplications cellular at site integration. Five extensive blocks open reading frame corresponding to gag gene, presumed protease, pol and env genes, orf within long terminal repeat were readily discernible. Translation gag, involved three different translational frames produce...

10.1128/jvi.61.2.480-490.1987 article EN Journal of Virology 1987-02-01

int-2 is one of two cellular genes (int-1 and int-2) currently implicated in the genesis mammary carcinomas by mouse tumor virus may constitute a novel proto-oncogene. Using low-stringency hybridization with probes, we established that homologous exist variety mammalian species, including humans, but failed to detect related sequences other classes phyla. Recombinant bacteriophage clones single cosmid encompassing human gene were isolated characterized restriction enzyme mapping. A survey...

10.1128/mcb.6.2.502 article EN Molecular and Cellular Biology 1986-02-01

Background: Assessment of residual fragments (RFs) is a key step after treatment kidney stones. Objective: To evaluate differences in RFs estimation based on unenhanced computerized tomography (CT) versus X-rays/ultrasound retrograde intrarenal surgery (RIRS) for Design: A retrospective analysis data from 20 centers adult patients who had RIRS was done (January 2018–August 2021). Methods: Exclusion criteria: ureteric stones, anomalous kidneys, bilateral renal Patients were divided into two...

10.1177/17562872231198629 article EN cc-by-nc Therapeutic Advances in Urology 2023-01-01

Background and objective Machine learning (ML) is a subset of artificial intelligence that uses data to build algorithms predict specific outcomes. Few ML studies have examined percutaneous nephrolithotomy (PCNL) Our was build, streamline, temporally validate, use models for prediction PCNL outcomes (intensive care admission, postoperative infection, transfusion, adjuvant treatment, complications, visceral injury, stone-free status at follow-up) using comprehensive national database (British...

10.1016/j.euf.2024.01.011 article EN cc-by-nc-nd European Urology Focus 2024-02-02

To assess the relationship of white blood cell count (WBC) and other routinely collected inflammatory clinical markers including stone size, position, medical expulsive therapy use (MET), with spontaneous passage (SSP) in a large contemporary cohort patients acute ureteric colic, as there are conflicting data on role WBC SSP colic.Multicentre retrospective study coordinated by British Urology Researchers Surgical Training (BURST) Research Collaborative at 71 secondary care hospitals across...

10.1111/bju.14777 article EN BJU International 2019-04-19

Y chromosome microdeletion is the most important genetic cause of impairment spermatogenesis. Nevertheless, a significant proportion patients with spermatogenic failure do not have this condition. This study investigated expression level AZF genes, DDX3Y (DBY), RBMY1, DAZ and TSPY in testicular tissues 42 subjects impaired spermatogenesis compared 33 normal Histopathological evaluation was performed all were classified according to Johnsen Score. Transcript amounts determined by...

10.1093/molehr/gam057 article EN Molecular Human Reproduction 2007-09-19

In the course of analyzing sites proviral integration in tumors induced by mouse mammary tumor virus (MMTV), we have isolated recombinant DNA clones corresponding to 5' and 3' ends four endogenous MMTV proviruses present BALB/c BR6 mice. This has permitted structural characterization each locus detailed restriction mapping preparation probes specific for cellular sequences flanking provirus. These been used trace segregation patterns proviruses, designated Mtv-8, Mtv-9, Mtv-17, Mtv-21, a...

10.1128/jvi.59.3.535-544.1986 article EN Journal of Virology 1986-09-01

Renal stones are common, with a lifetime prevalence of 10% in adults. Global incidence is increasing due to increases obesity and diabetes, these patient populations being more likely suffer renal stone disease. Flank pain from (renal colic) the most common cause emergency admission UK urology departments. Stones commonly develop lower pole kidney (in ~35% cases) here least pass without intervention. Currently there three technologies available within National Health Service remove stones:...

10.1186/s13063-020-04326-x article EN cc-by Trials 2020-06-04
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