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Research Areas
- Prion Diseases and Protein Misfolding
- Agriculture, Soil, Plant Science
- Metallurgy and Material Science
- Amino Acid Enzymes and Metabolism
- Recycling and Waste Management Techniques
- Alzheimer's disease research and treatments
- Chemical Synthesis and Characterization
- Nuclear Physics and Applications
- Distributed systems and fault tolerance
- Catalytic Processes in Materials Science
- Agriculture and Biological Studies
- Weed Control and Herbicide Applications
- Biological Research and Disease Studies
- Molten salt chemistry and electrochemical processes
- Parallel Computing and Optimization Techniques
- Alcoholism and Thiamine Deficiency
- Enzyme Production and Characterization
- Inorganic Fluorides and Related Compounds
- Parkinson's Disease Mechanisms and Treatments
- Radioactive element chemistry and processing
University of Washington Bothell
2016
Hypochlorous acid (HOCl) is produced naturally by neutrophils and other cells to kill conventional microbes in vivo. Synthetic preparations containing HOCl can also be effective as microbial disinfectants. Here we have tested whether inactivate prions self-propagating protein amyloid seeds. Prions are deadly pathogens that notoriously difficult inactivate, standard disinfection protocols often inadequate. Recommended treatments for prion decontamination include strongly basic (pH ≥~12)...
10.1371/journal.ppat.1005914
article
EN
public-domain
PLoS Pathogens
2016-09-29
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