A5101462308- Nicotinic Acetylcholine Receptors Study
- Mitochondrial Function and Pathology
- Vagus Nerve Stimulation Research
- Immune Response and Inflammation
- IL-33, ST2, and ILC Pathways
- GABA and Rice Research
- Immunodeficiency and Autoimmune Disorders
- Neuroscience and Neural Engineering
- interferon and immune responses
- Vestibular and auditory disorders
- Fatty Acid Research and Health
- Respiratory Support and Mechanisms
- Circadian rhythm and melatonin
- Cancer, Stress, Anesthesia, and Immune Response
- Phytoestrogen effects and research
- S100 Proteins and Annexins
- Healthcare and Venom Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Diverse Scientific Research Studies
- Inflammasome and immune disorders
- Medicinal Plant Research
- Barrier Structure and Function Studies
Union Hospital
2016-2022
Huazhong University of Science and Technology
2013-2022
Taihe Hospital
2021
Wuhan Union Hospital
2021
Indiana University – Purdue University Indianapolis
2019
First Affiliated Hospital of Zhengzhou University
2019
Providence College
2014-2015
Union Hospital
2013
The cholinergic anti-inflammatory pathway connects the immune response system and nervous via vagus nerve. key regulatory receptor is
Abstract Background The cholinergic anti-inflammatory pathway (CAP) connects the immune response system and nervous via vagus nerve. key regulatory receptor is α7-subtype of nicotinic acetylcholine (α7nAChR), which localized on surface cells system. CAP has been proved to be effective in suppressing inflammation responses acute lung injury (ALI). Dendritic (DCs), important antigen-presenting (APCs), also express α7nAChR. They not only play an role priming but participating pathological...
INTRODUCTION: Ca2+ release from sarcoplasmic reticulum (SR) is known to contribute the pacemaker activity in embryonic stem cells (ESC) derived cardiomyocytes (CMs). Mitochondria are participate cycling. Nevertheless, role of mitochondria unclear. We studied mitochondrial flux spontaneously ESC CMs. METHODS: CMs were Wt and ryanodine receptor type 2 knockout (RYR2-/-) mouse ESC. Action potentials (APs) recorded by perforated whole-cell current-clamp. Cytoplasmic transients determined Fluo-4...
Introduction: Ca2+ release from the sarcoplasmic reticulum (SR) is known to contribute spontaneous activity via cytoplasmic Na+-Ca2+ exchanger (NCX). Mitochondria are participate in cycling. We studied role of mitochondrial flux spontaneously embryonic stem cells (ESC)-derived CMs. Methods: CMs were derived wild type (Wt) and ryanodine receptor 2 knockout (RYR2-/-) mouse ESCs differentiated for 19-21 days. Action potentials (APs) recorded by perforated whole cell current-clamp. Cytoplasmic...