Alternating macrocyclization and polymerization was observed in dynamic nitroaldol reaction systems. The of an aromatic dialdehyde reacting with linear α,ω‐dinitroalkanes even numbers carbon atoms favored the formation lowellane macrocycles, while reactions involving dinitrocompounds consisted odd promoted polymerization. folding patterns alkyl chains played important factor determining outcome reactions.

The Gram-negative, opportunistic pathogen Pseudomonas aeruginosa has become a serious threat to global health, with increasing resistance towards even the most potent antibiotics. Like other bacteria, produces number of virulence factors that promote its pathogenicity. Of these, metallophores constitute an important group, able scavenge metal ions from surrounding environment secure metabolic functions bacterium. Pseudomonads produce iron-chelating metallophore (siderophore) pyochelin (PCH),...

Dynamic covalent gels are synthesized from an aromatic trialdehyde and α,ω-dinitroalkanes via the nitroaldol reaction in organic solvents. The gelation process can be fine-tuned by changing starting nitroalkanes, solvents, feed concentration, catalyst loading, or temperature. resulting organogels demonstrate good structural integrity excellent self-healing ability. Intact xerogels produced upon drying, without damaging network, solvent-free network recover its gel form presence of solvent....

Through a dynamic polymerization and self-sorting process, range of lowellane macrocycles have been efficiently generated in nitroaldol systems composed aromatic dialdehydes aliphatic or dinitroalkanes. All identified show composition two repeating units, resulting tetra-β-nitroalcohols different structures. The effects building block structure on the macrocyclization process demonstrated, influence from solvent has explored. In general, formation lowellanes were amplified response to...

Abstract Complex dynamic systems displaying interdependency between nitroaldol and boronic ester reactions have been demonstrated. Nitroalkane‐1,3‐diols, generated by the reaction, were susceptible to formation with different acids in aprotic solvents, whereas hydrolysis of esters occurred presence water. The led significant stabilization adducts under basic conditions. use bifunctional building blocks was furthermore established, allowing for main chain nitroaldol‐boronate dynamers as well...

The opportunistic pathogen Pseudomonas aeruginosa develops increasing resistance toward even the most potent antibiotics. Like other bacteria, produces a number of virulence factors including metallophores, which constitute an important group. Pseudomonads produce iron-chelating metallophore (siderophore) pyochelin, which, in addition to its iron-scavenging ability, is effector for transcriptional regulator PchR FeIII-bound form (ferripyochelin). In present study, docking studies predicted...

Alternating macrocyclization and polymerization was observed in dynamic nitroaldol reaction systems. The of an aromatic dialdehyde reacting with linear α,ω-dinitroalkanes even numbers carbon atoms favored the formation lowellane macrocycles, while reactions involving dinitrocompounds consisted odd promoted polymerization. folding patterns alkyl chains played important factor determining outcome reactions.

Through a dynamic polymerization and self-sorting process, range of lowellane macrocycles have been efficiently generated in nitroaldol systems composed aromatic dialdehydes aliphatic or dinitroalkanes. All identified show composition two repeating units, resulting tetra-β-nitroalcohols different structures. The effects the building block structure on macrocyclization process demonstrated, influence from solvent has explored. In general, formation lowellanes was amplified response to...

Dynamic covalent gels have been synthesized from an aromatic trialdehyde and α,ω-dinitroalkanes via the nitroaldol reaction in organic solvents. The gelation process could be finetuned by changing starting nitroalkanes, solvents, feed concentration, catalyst loading, or temperature. resulting organogels demonstrated good structural integrity excellent self-healing ability. Intact xerogels were produced upon drying, without damaging network, solvent-free network recover its gel form presence...

Complex dynamic systems displaying interdependency between nitroaldol and boronic ester reactions have been demonstrated. Nitroalkane-1,3-diols, generated by the reaction, were susceptible to formation with different acids in aprotic solvents, whereas hydrolysis of esters occurred presence water. The led significant stabilization adducts under basic conditions. use bifunctional building blocks was furthermore established, allowing for main chain nitroaldol-boronate dynamers as well complex...