- Fungal Biology and Applications
- Mycorrhizal Fungi and Plant Interactions
- Periodontal Regeneration and Treatments
- Wound Healing and Treatments
- Antifungal resistance and susceptibility
- Chemical synthesis and alkaloids
- Electrospun Nanofibers in Biomedical Applications
- Stress Responses and Cortisol
- Food Quality and Safety Studies
- Phytochemistry and Bioactivity Studies
- Polysaccharides and Plant Cell Walls
- Lichen and fungal ecology
- Oral and Maxillofacial Pathology
- Fungal Infections and Studies
- Ion channel regulation and function
- Pain Mechanisms and Treatments
- Neuropeptides and Animal Physiology
- Dermatologic Treatments and Research
- Nasolacrimal Duct Obstruction Treatments
- Biochemical and Structural Characterization
- Nanocomposite Films for Food Packaging
- Hair Growth and Disorders
- Slime Mold and Myxomycetes Research
- Retinoids in leukemia and cellular processes
- Medicinal Plants and Bioactive Compounds
Taipei Medical University
2008-2022
Ministry of Health and Welfare
2015
Taichung Hospital
2015
Taipei Medical University Hospital
2007-2013
University of Pittsburgh
2008
Johns Hopkins University
2004
Abstract Human intervertebral disc (IVD) degeneration often initiated from the human nucleus pulposus (hNP) with aging leading to IVD destruction and extracellular matrix (ECM) depletion. Previously, we have successfully employed transforming growth factor‐β1 (TGF‐β1) promote chondrogenesis of mesenchymal progenitor cells (MPCs) immortalized stem cells. In this study, examine role TGF‐β1 in platelet‐rich plasma (PRP) on regeneration, including proliferation, redifferentiation, reconstitution...
Abstract A durable sandwich wound dressing system with high liquid absorbing, biocompatibility, and antibacterial properties was designed. Various solution weight ratios of collagen to chitosan were used immobilize on the polypropylene nonwoven fabric, which pregrafted acrylic acid (AA) or N ‐isopropyl acrylamide (NIPAAm) construct a membrane water easy removal, activity. Swelling activity membranes measured, healing enhancement by skin full‐thickness excision animal model examined. The...
Taiwanofungus Sheng H. Wu, Z.H. Yu, Y.C. Dai & C.H. Su is proposed as a new genus of lignicolous polypore, and Ganoderma comphoratum M. Zang designated its generic type. New combinations for two species are presented: T. camphoratus (M. Su) Su, salmoneus (T.T. Chang W.N. Chou) Su. known in Taiwan “niu-chang-chih”. shares many common charaters with Antrodia Antrodiella. Phylogenetic analysis based on sequence data derived from LSU rDNA indicates that neither clusters Antrodia, nor only...
1. The effects of beta-endorphin and morphine on thermoregulatory responses unanaesthetized rabbits to different ambient temperatures (Ta) 2, 22 32 degrees C were assessed. 2. Intraventricular administration either or produced dose-dependent hypothermia at 2 Ta. At Ta the was brought about solely by a decrease in metabolic heat production. due metabolism an increase peripheral blood flow. However, Ta, there no changes rectal temperature response application. 3. Hypothermic greatly...
Asthma is a chronic disease characterized by airway inflammation caused the dysregulated production of cytokines secreted allergen-specific type 2 T helper (Th2) cells. Antrodia camphorata commonly used fungus in Asian folk medicine, and A. polysaccharides are reported to possess anti-cancer activities. In this study, immunomodulatory effects purified fractionated (GF2) from on dendritic cells (DCs) their potential preventive against ovalbumin (OVA) -induced asthma were investigated....
Taiwanofungus camphoratus, a well-known Chinese medicine used in Taiwan, possesses several pharmacological functions, including anticancer effects. In the present study, we aimed to investigate novel effect by pretreating cancer cells with an ethanolic extract of T. camphoratus (TCEE) followed administration antifungal agent amphotericin B (AmB). Both TCEE and AmB showed significant dose-dependent cytotoxicity HT29 cells. Pretreatment nontoxic dose enhanced AmB. Furthermore, apoptotic cell...
Abstract SACCHACHITIN membranes, prepared from the waste residue of fruiting body Ganoderma taugae , were used in our previous study to enhance skin wound healing animal models. In present study, effects membrane on growth keratinocytes and activity matrix metalloproteinases (MMPs), as well wounds humans, estimated. Fresh human foreskin was employed source keratinocyte culture, a modified keratinocyte‐SFM medium supplemented with 0.2 ng/mL recombinant epidermal factor 30 μg/mL bovine...
The incidence of liver cancer, the second leading cause cancer-related deaths has increased over past few decades. Although recent treatments such as sorafenib are promising in patients with advanced hepatocellular carcinoma (HCC), response rates remain poor thereby warranting identification novel therapeutic agents against cancer. Herein, we investigated anti-cancer effect ergosterol (a secondary metabolite medicinal fungus) pretreatment followed by amphotericin B (AmB) treatment on cancer...
Taiwanofungus camphoratus (Tc) is a basidiomycete fungus that causes brown heart rot of the aromatic tree Cinnamomum kanehirae. The Tc fruiting bodies have been used to treat hangovers, abdominal pain, diarrhea, hypertension, and other diseases first by aboriginal Taiwanese later people in many countries.
Taiwanofungus camphoratus (synonym Antrodia camphorata ) is a widely used medicinal fungus in the folk medicine of Taiwan with several pharmacological features such as anti-inflammatory, liver protection, antihypertensive, and antioxidative activities. The ethanolic extract T. (TCEE) which contains abundant bioactive compounds including triterpenoids polysaccharides also has antitumor effects various human cancer cell lines. aims this study are to clarify TCEE on hepatocellular carcinoma...
There is emerging interest in the use of standardized virally inactivated human platelet lysate preparations rich GFs (growth factors) for cell cultures, therapy and clinical applications. In present paper, we report a simple process to prepare preparation TGF-beta1 (transforming growth factor-beta1), EGF (epidermal factor) IGF (insulin-like depleted PDGF (platelet-derived VEGF (vascular endothelial factor). Apheresis concentrates were treated by S/D (solvent/detergent) viral inactivation...