A5081551288- Renal Diseases and Glomerulopathies
- Renal Transplantation Outcomes and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Dialysis and Renal Disease Management
- Pharmacological Effects and Toxicity Studies
- Renal and Vascular Pathologies
- Vasculitis and related conditions
- Systemic Sclerosis and Related Diseases
- Neurological Complications and Syndromes
- Organ Transplantation Techniques and Outcomes
- Organ Donation and Transplantation
- Neurological and metabolic disorders
- Drug-Induced Adverse Reactions
- Chronic Lymphocytic Leukemia Research
- Systemic Lupus Erythematosus Research
- Cytomegalovirus and herpesvirus research
- COVID-19 Clinical Research Studies
- Metabolism and Genetic Disorders
- Electrolyte and hormonal disorders
- Blood Pressure and Hypertension Studies
- Genetic and Kidney Cyst Diseases
- Multiple Myeloma Research and Treatments
- Complement system in diseases
- Autoimmune Bullous Skin Diseases
- Nephrotoxicity and Medicinal Plants
University of Sousse
2021-2025
Hôpital Sahloul
2015-2024
Abstract Background In Tunisia, the prevalence of diabetes mellitus increased from 15.5% on 2016 to 23% by 2023. While Chronic Kidney Disease (CKD) stills most dreaded complications diabetes, studies chronic kidney disease non-dialysis diet are scarce. The aim this study was assess among Tunisian diabetic population based investigators’ specialty, demographic criteria (gender, age, duration and geographic distribution) diagnosis (albuminuria and/or eGFR). Methods This observational,...
Social responsibility (SR) in health is of paramount importance the development systems. It is, therefore, frequently presented as one solutions for healthcare improvement most developed countries. In addition, SR has been subject several publications West and Asia. However, absence African data on this motivated us to carry out study which aimed assess public hospitals terms kidney disease management, explore factors that influence it based perceptions patients nephrologists, suggest...
Cisplatin (Cisp) is an active cytotoxic agent that was found efficient in the treatment of various types solid tumors. Its nephrotoxic effect has been very well documented clinical oncology. Erythropoietin (EPO), a renal cytokine-regulating hematopoiesis, recently shown to exert important cytoprotective effects many experimental injuries. The aim this study explore whether EPO would protect against Cisp-induced apoptosis rat kidney. Adult Wistar rats were treated with saline solution as...
In kidney transplant, the use of immunosuppressive drugs, indispensable to avoid organ rejection, implies an increased risk several infectious and neoplastic diseases. Cutaneous infections have a high incidence in transplant recipients are diagnosed 55% 97% these patients. The objectives this study were identify most frequent skin diseases their clinical factors within population recipients.
<br>Living-donor kidney transplantation is a well-established treatment of end-stage renal disease in Tunisia. Over the years, concerns have increased about harmlessness donation. This longitudinal single center study was carried out to evaluate safety nephrectomy as well further medical and surgical outcomes among donors. We collected analyzed clinical, biological, biochemical size data at time M1, M3, M6, Y1, Y2, Y4 after donation measured by ultrasound. All donor nephrectomies performed...
Interferon-beta (IFNβ), the most widely prescribed medication for multiple sclerosis, is generally considered safe. Nevertheless, rare serious and/or life-threatening side effects have been reported such as thrombotic microangiopathy. A few mechanisms proposed to explain how interferon causes microangiopathy, but immunological studies unable pin this phenomenon down a single pathophysiologic pathway. The aim of article was report new mechanism explaining Interferon beta related...
<br>Povidone-iodine is a broad-spectrum antiseptic applied topically to treat wounds and prevent their infection. Despite the apparent innocuousness of this agent, several cases acute kidney injury (AKI) due iodine toxicity have been reported. We report case severe AKI that occurred in 32-year-old female three days after hysteroscopy for diagnosis primary sterility using povidone-iodine as local agent. made clinical tubular necrosis related view presentation high blood concentration. The...
A 43-year-old male was admitted to our hospital because of renal failure and arterial hypertension. He followed from the age 15 years for psychosis had no familial history disease. Investigations revealed sensorineural deafness, a microcytic hypochromic anemia with normal ferritin leading diagnosis β thalassemia minor nephrotic syndrome. Examination biopsy specimen demonstrated severe Ig nephropathy. No classic cause IgA nephropathy found. Review literature showed two previous reported cases...
chronic lymphocytic leukemia (CLL) patients have a high risk of occurrence secondary cancers. This is three times higher for all cancers and eight skin cancer. The coexistence CLL adenocarcinoma the prostate rare.We report case a66-year-old man who underwent radical prostatectomy carcinoma. final histopathological diagnosis Gleason 7 with incidental Rai stage I was made. No further investigations or treatment offered due to age low disease stage. At last follow-up 12 months, patient alive,...
Diabetes after kidney transplant is a common complication. It may increase the risk of cardiovascular disease and mortality transplant. The aim this study was to examine effects diabetes that developed on outcomes in recipients.This included renal allograft recipients without who received transplants from 2008 2019 our Department Nephrology at Sahloul Hospital (Tunisia). Demographic clinical data time events during period were collected. Patient graft survival rates analyzed. Patients with...
Aim: The effects of variants in IMPDH, UGT1A9, UGT1A8, UGT2B7 and SLCO1B1 genes on the efficacy safety mycophenolate mofetil (MMF) Tunisian population were investigated. Materials & methods: A total 245 kidney transplant patients being treated with MMF recruited cotreated cyclosporine or tacrolimus. Genotyping was performed using polymerase chain reaction-restriction fragment length polymorphism method. MMF, tacrolimus trough levels measured by immunoassay. AUC (AUC0-12hMPA) estimated a...
Acute interstitial nephritis (AIN) is a relevant cause of acute renal failure. Drugs are the predominant cause, followed by infections and idiopathic lesions. AIN, as form hypersensitivity reaction, an uncommon manifestation in setting human parasitic infections. We report case polyparasitic infection ( Giardia lamblia, Entamoeba coli, Endolimax nana) resulting severe biopsy-proven AIN 61-year-old male patient. Despite antiparasitic treatment corticosteroid therapy, during 6-month follow-up...
<br>Living donor kidney transplantation is the treatment of choice for patients with end-stage renal disease, especially where deceased programs are limited. There limited data on outcomes living donors (LKD) from developing countries, North Africa. The aim this study to evaluate prevalence hypertension (HTN) in LKD and analyze its risk factors. This a longitudinal monocentric study, who underwent nephrectomy donation between 2006 2015 were included. Ninety-two assessed. mean age at time was...
Plasma exchange (PE) is a non-selective apheresis technique that can be performed by filtration or centrifugation, allowing rapid purification of high molecular weight pathogenic substances. In nephrology, this widely prescribed as treatment. We report our experience
Urinary tract infections are the main infectious complications among kidney transplant recipients and considered as a potential risk factor for poor graft outcomes. However, factors of urinary controversial. The purpose our study was to estimate incidence predisposing in patients undergoing teaching hospital Sahloul, Tunisia.