A5055226370- Management of metastatic bone disease
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Bone Tumor Diagnosis and Treatments
- Sarcoma Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Orthopaedic implants and arthroplasty
- Oral and Maxillofacial Pathology
- Medical Imaging and Analysis
- Anatomy and Medical Technology
- Bone Tissue Engineering Materials
- Artificial Intelligence in Healthcare and Education
- 3D Printing in Biomedical Research
- Advanced Radiotherapy Techniques
- Surgical Simulation and Training
- Biomedical and Engineering Education
- Microfluidic and Capillary Electrophoresis Applications
- Healthcare Operations and Scheduling Optimization
- Anesthesia and Pain Management
- Inflammatory Biomarkers in Disease Prognosis
- Advanced X-ray and CT Imaging
- Neurofibromatosis and Schwannoma Cases
- Spinal Hematomas and Complications
- ATP Synthase and ATPases Research
- Cancer, Hypoxia, and Metabolism
Istituto Ortopedico Rizzoli
2019-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2022-2024
University of Bologna
2023-2024
Sapienza University of Rome
2022
Fondazione Poliambulanza Istituto Ospedaliero
2022
University of Padua
2022
Abstract Purpose In this study, we analyzed the use of a validated capture system (Spinal Adverse Events Severity system, SAVES V2) as first non-technical skill to properly face relevant problem surgical complications (SCs) and adverse events (AEs) in spinal surgery. Methods We retrospectively collected AEs occurring tertiary referral center for spine surgery from January 2017 2018 classified them according V2 system. compared collection with prospective performed without any classification...
CFR-PEEK is gaining popularity in spinal oncological applications due to its reduction of imaging artifacts and radiation scattering compared with titanium, which allows for better follow-up efficacy radiotherapy. We evaluated the use these materials treatment lumbar degenerative diseases (DDs) considered biomechanical potential carbon fiber relation modulus elasticity being similar that bone. Twenty-eight patients DDs were treated using CRF-PEEK instrumentation. The clinical radiographic...
OBJECTIVE The aim of this study was to compare the outcome intralesional gross-total resection (GTR) followed by high-energy particle therapy with en bloc and resections. METHODS A retrospective patients diagnosed primary osteogenic sarcoma (OGS) spine between 2009 2020 conducted. Demographic information, including age, affected site, tumor volume, Weinstein-Boriani-Biagini stage, collected. Additionally, information on metastases at diagnosis, length stay, operating time, complications,...
The use of three-dimensional (3D)-printed custom-made implants is spreading in the orthopedics field for reconstruction bone losses or joint replacement, thanks to their unparalleled versatility. In particular, this novel technology opens new perspectives formulate fixation strategies upper cervical region, sacrum and pelvis, where challenging. We report analyze literature concerning with 3D-printed personalized after tumor surgery, discuss two cases patients was used reconstruct anterior...
Abstract Background and Objective Oncological distal femur resections can leave a proximal too short to host stem. Reconstructive techniques are then challenging. The purpose of the study is compare implant survival, complication rate MSTS two different options. Methods We retrospectively divided 33 patients with primary bone tumours in Group 1 (16 reconstructed knee megaprosthesis augmentation, APC) 2 (17 total prosthesis, TFP). Less than 12 cm remaining were planned for all resections....
Pedicle stress fractures are an uncommon type of non-union often associated with contralateral neural arch interruption in young, active patients. Patients present long-lasting low back pain, and the diagnosis is usually delayed. Treatment generally conservative. Few cases treated surgically described literature, a high degree treatment heterogeneity no consensus on optimal treatment. A 24-year-old male, following sports-related trauma, developed persistent lower pain. Imaging revealed right...
Convolutional Neural Networks are being increasingly applied to the detection of anomalies in Computed Tomographies (CTs). The goal this paper is implement an automated Computer-Aided Detection (CADe) system for spinal lesions using CTs and pre-trained on commercial datasets. proposed pipeline works as follows. CADe takes input CT scans equipped with intuitive GUI allow physicians use it a support tool diagnoses. From scans, selects volumes containing vertebrae extracts 2D slices these...
Background/Objective: Surgical treatment of aneurysmal bone cysts (ABCs) can be challenging, especially in the spine. Non-surgical treatments such as with denosumab have shown promising results different osteolytic pathologies. This retrospective observational study aimed to evaluate long-term clinical and radiologic response patients ABCs mobile spine treated propose an updated algorithm. Methods: Six relapsed symptomatic were (120 mg subcutaneously on days 1, 8, 15, 29, every 4 weeks...
<title>Abstract</title> Background In spinal surgery adverse events (AE) and surgical complications (SC) significantly affect patient’s outcome quality of life. The duration has been investigated in different field as risk factor for complications. aim this study is to analyze the correlation between operative time surgery. Methods We retrospectively analyzed data collected prospectively a cohort 336 patients surgically treated diseases oncological degenerative origin single center, January...
Multiagent chemotherapy offers an undoubted therapeutic benefit to cancer patients, but is also associated with chronic complications in survivors. Osteoporosis affects the quality of life oncologic especially at paediatric age. However, very few studies have described extent loss bone mineral density (BMD) sarcoma patients. We analysed a retrospective series children and adolescents primary malignant tumours (52 osteosarcoma 31 Ewing sarcoma) retrieved their BMD diagnosis follow-up as...
We described an algorithm for the management of spinal metastases in which importance single parameters varies depending on when they are contemplated. Each patient follows his own "personal" sequential process does not necessarily consider all each time as some may be irrelevant purpose choosing type treatment that individual. For instance, a general poor condition with high "ASA" score is usually candidate surgery, regardless primary tumor nature or number metastases. this patient, most...
Describimos un algoritmo para el manejo de las metástasis espinales en que la importancia los parámetros individuales varía dependiendo del momento se contemplan. Cada paciente sigue su propio proceso secuencial "personal" no necesariamente considera todos cada vez, ya algunos pueden ser irrelevantes a hora elegir tipo tratamiento ese individuo. Por ejemplo, mal estado general con una puntuación alta "ASA" generalmente es candidato cirugía, independientemente naturaleza tumor primario o...
Microfluidic principles have been widely applied for more than 30 years to solve biological and micro-electromechanical problems. Despite the numerous advantages, microfluidic devices are difficult manage as their handling comes with several technical challenges. We developed a new portable tool, trainer (MT), that assesses operator skills may be used maintaining or improving ability inject fluid in inlet of vitro cell culture applications. After tests, we optimized MT tester reproduce real...
11532 Background: Limited are data on high-grade osteosarcoma occurring in the spine. Wide resection is recommended, but it a difficult and high morbidity procedure High-energy particle therapy has been recently used. The goal of this study was to examine treatment outcome patients with mobile Methods: Spine grade who underwent surgery at Rizzoli Institute between 2009 2020 were identified. Treatment, outcome, prognostic factors treated single institution examined. Results: Characteristics...