A5055788175- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Asthma and respiratory diseases
- Global Public Health Policies and Epidemiology
- COVID-19 and Mental Health
- Respiratory viral infections research
- Vitamin D Research Studies
- Climate Change and Health Impacts
- interferon and immune responses
- Atrial Fibrillation Management and Outcomes
- Retinal Imaging and Analysis
- T-cell and B-cell Immunology
- Inflammasome and immune disorders
- Immune Response and Inflammation
- Venous Thromboembolism Diagnosis and Management
- Immunodeficiency and Autoimmune Disorders
- Pharmaceutical Practices and Patient Outcomes
- Global Maternal and Child Health
- Healthcare professionals’ stress and burnout
- Child Nutrition and Water Access
- Ophthalmology and Visual Impairment Studies
- Child and Adolescent Psychosocial and Emotional Development
- S100 Proteins and Annexins
- Mental Health Treatment and Access
University of Sharjah
2018-2025
Wenzhou Medical University
2024
The University of Sydney
2024
Institute for Musculoskeletal Health
2024
Institute for Health Metrics and Evaluation
2023-2024
University of Washington
2023-2024
Royal North Shore Hospital
2024
Northern Sydney Local Health District
2024
Jimma University
2023
University of Electronic Science and Technology of China
2023
The COVID-19 pandemic is likely to increase anxiety levels within the community and in particular medical students who are already considered psychologically vulnerable groups. Since outbreak, no study has yet estimated effect of this on university UAE or its impact psychological well-being students.We surveyed 1485 (comprising dental) non-medical across 4 emirates UAE. We used an online platform assess knowledge, sources information, changes hygienic behavior, perceptions fear worry using...
<h2>Summary</h2><h3>Background</h3> Gout is an inflammatory arthritis manifesting as acute episodes of severe joint pain and swelling, which can progress to chronic tophaceous or erosive gout, both. Here, we present the most up-to-date global, regional, national estimates for prevalence years lived with disability (YLDs) due gout by sex, age, location from Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2021, well forecasted 2050. <h3>Methods</h3> YLDs 1990 2020 were estimated...
The WHO Global Oral Health Action Plan has set an overarching global target of achieving a 10% reduction in the prevalence oral conditions by 2030. Robust and up-to-date information on burden is paramount to monitor progress towards this target. aim systematic data analysis was produce global, region, country-level estimates of, disability-adjusted life-years (DALYs) attributed to, untreated caries, severe periodontitis, edentulism, other disorders, lip cavity cancer, orofacial clefts from...
Abstract Background The psychosocial impact of previous infectious disease outbreaks in adults has been well documented, however, there is limited information on the mental health COVID-19 pandemic and children United Arab Emirate (UAE) community. aim this study was to explore anxiety levels among UAE identify potential risk protective factors for well-being during pandemic. Methods Using a web-based cross-sectional survey we collected data from 2200 self-selected, assessed volunteers their...
Mitogen-activated protein kinases (MAPK) and NF-kappaB (NF-κB) pathway regulate many cellular processes are essential for immune cells function. Their activity is controlled by dual-specificity phosphatases ( DUSPs ). A comprehensive analysis of publicly available gene expression data sets human airway epithelial (AECs) infected with SARS-CoV-2 identified DUSP1 DUSP5 among the lowest induced transcripts within these pathways. These proteins known to downregulate MAPK NF-κB pathways; their...
Introduction: The COVID-19 pandemic is likely to increase anxiety levels within the community and in particular medical students who are already considered psychologically vulnerable groups. Since outbreak, no study has yet estimated effect of this on university UAE or its impact psychological well-being students. Methods: In study, we surveyed 1485 (comprising dental) non-medical across 4 emirates UAE. We used an online platform assess knowledge, sources information, changes hygienic...
The immune system is tightly regulated by the activity of stimulatory and inhibitory receptors. This homeostasis usually disturbed during chronic viral infection. Using publicly available transcriptomic datasets, we conducted in silico analyses to evaluate expression pattern 38 selected receptors (IRs) associated with different myeloid lymphoid cells coronavirus disease 2019 (COVID-19) Our revealed a overall upregulation IR mRNA severe acute respiratory syndrome 2 (SARS-CoV-2) A large number...
Abstract The economic growth has paralleled the rise of diabetes and its complications in multiethnic population United Arab Emirates (UAE). Previous studies have shown that characteristics is variable across different ethnicities. objective this study was to compare prevalence risk factors between UAE nationals expatriate’s ethnic groups using data from National Diabetes Lifestyle Study (UAEDIAB). made one-fourth (n = 797, 25%) total cohort remaining 75% belonged immigrants. Across...
Objectives Remdesivir is one of the most widely recommended and used medications for COVID-19 treatment. However, different outcomes have been reported hospitalized patients with treated remdesivir. Specifically, effect timing remdesivir initiation (from patient’s symptom onset) on clinical in has not investigated. Methods This a retrospective cohort study or without remdisivir. The primary outcome was recovery rate, defined as improvement discharge by day 14 onset. secondary need intensive...
Immune homeostasis is disturbed during severe viral infections, which can lead to loss of tolerance self-peptides and result in short- or long-term autoimmunity. Using publicly available transcriptomic datasets, we conducted an in-silico analyses evaluate the expression levels 52 autoantigens, known be associated with 24 autoimmune diseases, SAR-CoV-2 infection. Seven autoantigens (MPO, PRTN3, PADI4, IFIH1, TRIM21, PTPRN2, TSHR) were upregulated whole blood samples. MPO TSHR overexpressed...
Nirmatrelvir plus ritonavir received Emergency Use Authorization for treating mild to moderate COVID-19 in high-risk patients. Its efficacy against the Omicron variant of SARS-CoV-2 remains uncertain. This retrospective cohort study assessed effect nirmatrelvir-ritonavir preventing severe disease progression and long COVID symptoms after acute non-hospitalized adults. SALAMA medical records from Dubai's healthcare centers between May 22, 2022, April 30, 2023, were used identify 7290 eligible...
Adverse drug reactions (ADRs) represent a major burden on the healthcare system. Chronic kidney disease (CKD) patients are particularly vulnerable to ADRs because they usually multiple regimens, have comorbidities, and of alteration in their pharmacokinetics pharmacodynamic parameters. Therefore, one step towards reducing this is identify who at increased risk an ADR. To develop method identifying CKD for experiencing during hospitalisation. Factors associated with were identified by using...
Besides the respiratory system, severe acute syndrome-coronavirus 2 (SARS-CoV-2) infection was shown to affect other essential organs such as kidneys. Early kidney involvement during course of associated with worse outcomes, which could be attributed direct SARS-CoV-2 cells. In this study, effect commonly used medications on expression receptor, angiotensin-converting enzyme (ACE)2, and TMPRSS2 protein in tissues evaluated. This done by silico analyses publicly available transcriptomic...
T-helper 17 cell-mediated response and their effector IL-17 cytokine induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a major cause of COVID-19 disease severity death. Therefore, the study aimed to determine if level in saliva mirrors its circulatory hence can be used as non-invasive biomarker for severity.Interleukin-17 (IL-17) was evaluated ELISA blood 201 adult patients with different levels severity. The also associated severity, need mechanical...
Abstract The COVID-19 pandemic originated in Wuhan, China on December 31 st and spread into international borders, leading to a public health crisis complete shutdown of countries. strict quarantine measures taken by governments kept large number people, around the world, isolation affected many aspects people’s lives. These unprecedented changes triggered wide variety psychological problems ranging from panic disorders, anxiety depression. In this study, we aim explore levels among parents,...
Objectives: Providing medical care during a global pandemic exposes healthcare workers (HCW) to high level of risk, causing anxiety and stress. This study aimed assess the prevalence psychological distress among HCWs COVID-19. Methods: We invited from 3 hospitals across United Arab Emirates (UAE) participate in an anonymous online survey between April 19–May 3, 2020. The GAD-7 K10 measures were used distress. Logistic regression models assessed associations knowledge, attitude, worry, levels...
Objectives Our study aims at comparing the efficacy and safety of IFN-based therapy (lopinavir/ritonavir, ribavirin, interferon β-1b) vs. favipiravir (FPV) in a cohort hospitalized patients with non-critical COVID-19. Methods Single center observational (interferon β-1b, lopinavir/ritonavir) FPV COVID-19 patients. Allocation to either treatment group was non-random but based on changes national protocols rather than physicians’ selection (quasi-experimental). We examined association between...
Drug-related problems (DRPs) are prevalent in critical care settings and can be life-threatening. Involving clinical pharmacists (CP) within the team is recommended to optimize therapy improve patient survival.