A5058723899- Biochemical and Molecular Research
- Enzyme Structure and Function
- Cancer, Hypoxia, and Metabolism
- Immunotherapy and Immune Responses
- RNA Interference and Gene Delivery
- Inhalation and Respiratory Drug Delivery
The University of Texas at Austin
2021-2023
Although mRNA lipid nanoparticles (LNPs) are highly effective as vaccines, their efficacy for pulmonary delivery has not yet fully been established. A major barrier to this therapeutic goal is instability during aerosolization local delivery. This imparts a shear force that degrades the cargo and therefore reduces cell transfection. In addition remaining stable upon aerosolization, LNPs must also possess aerodynamic properties achieve deposition in clinically relevant areas of lungs. We...
Biomolecular visualization skills are paramount to understanding key concepts in the biological sciences, such as structure-function relationships and molecular interactions. Various programs allow a learner manipulate 3D structures, biomolecular modeling promotes active learning, builds computational skills, bridges gap between two dimensional textbook images three dimensions of life. A critical skill this area is model protein site, displaying parts macromolecule that can interact with...
Biomolecular visualization skills are paramount to understanding key concepts in the biological sciences, such as structure-function relationships and molecular interactions. Various programs allow a learner manipulate 3D structures, biomolecular modeling promotes active learning, builds computational skills, bridges gap between two dimensional textbook images three dimensions of life. A critical skill this area is model protein site, displaying parts macromolecule that can interact with...