- Poisoning and overdose treatments
- Alcoholism and Thiamine Deficiency
- Drug-Induced Hepatotoxicity and Protection
- Pediatric Pain Management Techniques
- Cannabis and Cannabinoid Research
- Prenatal Substance Exposure Effects
- COVID-19 and healthcare impacts
- Pesticide Exposure and Toxicity
- Silymarin and Mushroom Poisoning
- Renal function and acid-base balance
- Opioid Use Disorder Treatment
- Leaf Properties and Growth Measurement
- Alkaloids: synthesis and pharmacology
- Dental Anxiety and Anesthesia Techniques
- Electroconvulsive Therapy Studies
- Psychedelics and Drug Studies
- Plant-based Medicinal Research
- Cardiac electrophysiology and arrhythmias
- Pain Mechanisms and Treatments
- Treatment of Major Depression
- Pain Management and Opioid Use
- Anesthesia and Sedative Agents
- Takotsubo Cardiomyopathy and Associated Phenomena
- Neurobiology and Insect Physiology Research
- Phytochemistry and Bioactivity Studies
University of Utah
2019-2025
Washington Poison Center
2017-2019
Oregon Health & Science University
2018-2019
Virginia Commonwealth University Medical Center
2016-2017
Virginia Commonwealth University
2016
Brigham Young University
2008-2012
The position of the American College Medical Toxicology (ACMT) and Academy Clinical (AACT) is as follows:Fentanyl its analogs are potent opioid receptor agonists, but ...
Abstract Background: The COVID-19 pandemic caused a significant backlog in the UK National Health Service (NHS), with 7.6 million patients awaiting consultant appointments as of August 2024. A major consequence this was surge urgent suspected cancer (USC) referrals, which rose by 27% compared to pre-pandemic levels without proportional increase detection rates. General Practitioners (GPs) often default USC bypassing initial investigations, strains secondary care services. C Signs, an AI-led...
Background: Amanita muscaria (AM) and A. pantherina (AP) contain ibotenic acid muscimol may cause both excitatory sedating symptoms. Gastrointestinal (GI) symptoms are not classically described but have been reported. There relatively few reported cases of poisoning with these mushrooms in North America.Methods: This is a retrospective review ingestions containing to United States regional poison center from 2002–2016. Cases were included if identification was made by mycologist or AM...
Abstract Background Serotonin toxicity is a common cause of drug-induced altered mental status. However, data on the causes serotonin toxicity, symptomatology, complications, and rate antidotal treatment are limited. Methods This study evaluated cases in ToxIC registry, an international database prospectively collected seen by medical toxicologists. was diagnosed bedside evaluation toxicology specialists explicit criteria were not used. The searched for “serotonin syndrome” between January...
Background Prompt acetylcysteine treatment with standard doses (300 mg/kg over 21 h in divided doses) is almost universally effective preventing hepatotoxicity after paracetamol (acetaminophen) overdose. However, reported despite early when concentrations exceed 300 mg/L (1,985 μmol/L) at 4 h. Prior studies evaluating high-dose to treat high-risk ingestions have shown mixed results. We compared outcomes patients receiving or acetylcysteine.
Background: Salicylates are usually rapidly absorbed and quickly measurable in serum. An undetectable serum salicylate concentration ([ASA]) may occur early after ingestion be interpreted as evidence of non-exposure not repeated. Although cases delayed detection reported rarely, the risk factors associated with this phenomenon known.Research question: What an [ASA] poisoning?Methods: Records from a single regional poison center were searched 2002 to 2016 for toxicity treated bicarbonate > 30...
Introduction: Unintentional mothball ingestions may cause serious toxicity in small children. Camphor, naphthalene, and paradichlorobenzene mothballs are difficult to distinguish without packaging. Symptoms management differ based on the ingested compound. Previous studies have used a variety of antiquated, impractical potentially dangerous techniques identify mothballs. The goal this study is discover simplified identification technique using materials readily available an emergency...
The Ilama is an important agricultural livestock in much of South America. llama increasing popularity the United States as a companion animal. Little work has been done to improve production using modern technology. A paucity information available regarding genome. We report construction bacterial artificial chromosome (BAC) library about 196,224 clones vector pECBAC1. Using flow cytometry and bovine, human, mouse, chicken controls, we determined genome size be<mml:math...
To examine the clinical outcomes of topical lidocaine exposures in pediatric patients reported to National Poison Data System (NPDS). We performed a retrospective review NPDS with toxicity from 2000 2020. Specific data analyzed were age, exposure chronicity, medical outcome, effects, treatments, and disposition. Narrative case records requested poison centers. Of 37 cases identified, mean age was 5 years distribution 1- 0 days (n = 8), 1 24 months 11), 2-18 18). Exposure chronicity acute 33...
Ethylene glycol poisoning causes metabolic acidosis, organ injury, and death. testing is unavailable in many areas. Our laboratory uses an automated glycerol dehydrogenase enzymatic assay to screen for ethylene glycol. We sought determine how often results were available within 12 h of the first dose fomepizole.