A5070137432- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Cervical and Thoracic Myelopathy
- Musculoskeletal pain and rehabilitation
- Anesthesia and Pain Management
- Medical Imaging and Analysis
- Scoliosis diagnosis and treatment
- Pelvic and Acetabular Injuries
- Spinal Hematomas and Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Clinical practice guidelines implementation
- Opioid Use Disorder Treatment
- Surgical site infection prevention
- Orthopaedic implants and arthroplasty
- Health Systems, Economic Evaluations, Quality of Life
- Management of metastatic bone disease
- Hip and Femur Fractures
- Diversity and Career in Medicine
- Pain Management and Opioid Use
- Spinal Cord Injury Research
- Nerve Injury and Rehabilitation
- Intraoperative Neuromonitoring and Anesthetic Effects
- Infectious Diseases and Tuberculosis
- Hip disorders and treatments
- Healthcare Policy and Management
Thomas Jefferson University
2016-2025
Rothman Institute
2016-2025
Thomas Jefferson University Hospital
2015-2025
Rothman Orthopaedics
2019-2025
North American Spine Society
2018-2024
The Medical Device (United Kingdom)
2024
Stryker (United States)
2018-2024
Louisiana State University
2018-2024
Institute of Semitic Studies
2023-2024
Temple University Hospital
2006-2024
Background: We studied the incidence, prevalence, and radiographic progression of symptomatic adjacent-segment disease, which we defined as development new radiculopathy or myelopathy referable to a motion segment adjacent site previous anterior arthrodesis cervical spine.Methods: A consecutive series 374 patients who had total 409 arthrodeses for treatment spondylosis with myelopathy, both, were followed maximum twenty-one years after operation. The annual incidence disease was percentage...
Surgery for spinal stenosis is widely performed, but its effectiveness as compared with nonsurgical treatment has not been shown in controlled trials.
ContextLumbar diskectomy is the most common surgical procedure performed for back and leg symptoms in US patients, but efficacy of relative to nonoperative care remains controversial.ObjectiveTo assess surgery lumbar intervertebral disk herniation.Design, Setting, PatientsThe Spine Patient Outcomes Research Trial, a randomized clinical trial enrolling patients between March 2000 November 2004 from 13 multidisciplinary spine clinics 11 states. Patients were 501 candidates (mean age, 42 years;...
Management of degenerative spondylolisthesis with spinal stenosis is controversial. Surgery widely used, but its effectiveness in comparison that nonsurgical treatment has not been demonstrated controlled trials.Surgical candidates from 13 centers 11 U.S. states who had at least 12 weeks symptoms and image-confirmed were offered enrollment a randomized cohort or an observational cohort. Treatment was standard decompressive laminectomy (with without fusion) usual care. The primary outcome...
This retrospective, questionnaire-based investigation evaluated iliac crest bone graft (ICBG) site morbidity in patients having undergone a single-level anterior cervical discectomy and fusion (ACDF) procedure performed by single surgeon (T.J.A.).To evaluate acute chronic problems associated with ICBG donation, particularly long-term functional outcomes impairments caused donation.Anterior procedures frequently use autologous to facilitate osseous union. Although offers several advantages...
Concurrent, prospective, randomized, and observational cohort study.To assess the 4-year outcomes of surgery versus nonoperative care.Although randomized trials have demonstrated small short-term differences in favor surgery, long-term comparing surgical to treatment remain controversial.Surgical candidates with imaging-confirmed lumbar intervertebral disc herniation meeting SPORT eligibility criteria enrolled into (501 participants), cohorts (743 participants) at 13 spine clinics 11 US...
In Brief Study Design. Randomized trial and concurrent observational cohort study. Objective. To compare 4 year outcomes of surgery to nonoperative care for spinal stenosis. Summary Background Data. Surgery stenosis has been shown be more effective compared treatment over 2 years, but longer-term data have not analyzed. Methods. Surgical candidates from 13 centers in 11 US states with at least 12 weeks symptoms confirmatory imaging were enrolled a randomized (RC) or (OC). Treatment was...
In Brief Study Design. Concurrent, prospective, randomized, and observational cohort study. Objective. To assess the 4-year outcomes of surgery versus nonoperative care. Summary Background Data. Although randomized trials have demonstrated small short-term differences in favor surgery, long-term comparing surgical to treatment remain controversial. Methods. Surgical candidates with imaging-confirmed lumbar intervertebral disc herniation meeting SPORT eligibility criteria enrolled into (501...
Questions remain as to the effect that obesity has on patients managed for symptomatic lumbar disc herniation. The purpose of this study was determine if affects outcomes following treatment herniation.An as-treated analysis performed enrolled in Spine Patient Outcomes Research Trial A comparison made between with a body mass index <30 kg/m² (nonobese) (n = 854) and those ≥30 (obese) 336). Baseline patient demographic clinical characteristics were documented. Primary secondary measured at...
There has been little enthusiasm for somatosensory evoked potential monitoring in cervical spine surgery as a result, part, of the increased risk motor tract injury at this level, to which may be insensitive. Transcranial electric allows assessment tracts; therefore, we compared transcranial and during determine temporal relationship between changes potentials demonstrated by each type neurological sequelae identify patient-related surgical factors associated with intraoperative...
A prospective, multicenter, cross-sectional analysis of data from the National Spine Network database.To compare relative impact radicular and axial symptoms associated with disease cervical spine on general health as measured by SF-36 Health Survey, to these among patients varying age symptom duration.Degenerative disorders can cause debilitating neck arm pain. Physicians generally treat radiculopathy more aggressively than pain alone, although it has never been shown that presence leads a...
A retrospective review of all patients surgically treated for adjacent segment disease the cervical spine over a 20-year period.To determine clinical and radiographic success discectomy with interbody grafting corpectomy strut in treatment spine.Up to 25% undergoing anterior fusion have new due degeneration an within 10 years. The surgical these has not been reported.Thirty-eight were by or grafting. Arthrodesis was evaluated flexion-extension lateral radiographs outcomes assessed using...
Background: An increased rate of pseudarthrosis has been documented following posterolateral lumbar spine grafting in patients who smoke. This same relationship assumed for anterior cervical interbody grafting, but to our knowledge it never proven. study compared the long-term radiographic and clinical results smokers nonsmokers had undergone arthrodesis with autogenous bone graft multilevel decompression treatment radiculopathy or myelopathy, both. Methods: One hundred ninety were followed...
Existing studies suggest a relatively high incidence of dysphagia after anterior cervical decompression and fusion (ACDF). The majority these studies, however, are retrospective in nature lack control group.We therefore (1) prospectively determined the severity ACDF using lumbar patients as group; (2) which factors, if any, associated with increased postoperative dysphagia.Patients undergoing either one- or two-level (n=38) posterior (n=56) were followed. Baseline patient characteristics...
In Brief Study Design. vitro comparison of four reconstruction techniques following transforaminal lumbar interbody fusion in a human cadaveric model. Introduction. Transforaminal (TLIF) is relatively new technique that avoids the morbidity an anterior approach and nerve root manipulation posterior fusion. This study measured effects TLIF on overall segmental flexibility spine using different spinal implant configurations. Summary Background Data. Anterior fusion, combined anterior–posterior...
In Brief Study Design. A prospective, randomized, controlled, multicenter clinical study was conducted. Objective. To compare the and radiographic outcomes of patients treated with OP-1 (BMP-7) Putty to autogenous iliac crest bone graft for one-level uninstrumented posterolateral fusion lumbar spine following decompressive laminectomy treatment symptomatic degenerative spondylolisthesis spinal stenosis. Background. Preclinical studies have demonstrated that osteoinductive recombinant human...
Survey-based descriptive study.To study relationships between surgeon-specific factors and surgical approach to degenerative diseases of the cervical spine.Geographic variations in rates spine surgery are significant within United States. Although surgeon density correlates with spinal surgery, other reasons for variation such as poorly understood.A total 22 orthopedic surgeons 8 neurosurgeons varied ages geographic regions answered questions regarding need approach, use fusion...