Antoni Białek

ORCID: 0000-0001-8838-2805
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About
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Research Areas
  • Advancements in Transdermal Drug Delivery
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Bee Products Chemical Analysis
  • Hydrogels: synthesis, properties, applications
  • 3D Printing in Biomedical Research
  • Polysaccharides and Plant Cell Walls
  • Advanced Drug Delivery Systems
  • Additive Manufacturing and 3D Printing Technologies
  • Polysaccharides Composition and Applications
  • Dermatology and Skin Diseases
  • Ocular Surface and Contact Lens

Poznan University of Medical Sciences
2022-2025

Agomelatine (AGM) is an effective antidepressant with low oral bioavailability due to intensive hepatic metabolism. Transdermal administration of agomelatine may increase its and reduce the doses necessary for therapeutic effects. However, transdermal delivery requires crossing stratum corneum barrier. For this purpose, use microneedles efficiency administration. The aim study was prepare agomelatine-loaded hydrogel suitable coating drug AGM. optimized formulations were subjected...

10.3390/molecules30020322 article EN cc-by Molecules 2025-01-15
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