Living organisms use spatially controlled expansion and contraction of soft tissues to achieve complex three-dimensional (3D) morphologies movements thereby functions. However, replicating such features in man-made materials remains a challenge. Here we report an approach that encodes 2D hydrogels with temporally growth (expansion contraction) create 3D structures programmed motions. This uses temperature-responsive locally programmable degrees rates swelling shrinking. method simultaneously...

The reconstruction of full-thickness chest wall defects is a challenging problem for thoracic surgeons, particularly after wide resection the that includes sternum. location and size defect play major role when selecting method reconstruction, while acceptable cosmetic functional results remain primary goal. Improvements in preoperative imaging techniques materials have an important planning performing with low morbidity rate. In this report, we describe anterior patient-specific custom-made...

Many burns that occur in the first two decades of life are accidental and preventable.The aim this study was to determine demographic features, mortality, other factors associated with pediatric Istanbul, Turkey. METHODSOur retrospective included 375 hospitalized patients (225 male, 150 female; mean age 4.07±3.79;range 0.2 16 years) aged years or less admitted between January 2005 2009.Each child's medical record reviewed mechanism burn, place residence, total body surface area (TBSA),...

Syringocystadenocarcinoma papilliferum is the rare malignant counterpart of a more common, benign adnexal neoplasm known as syringocystadenoma papilliferum. Review literature identified 21 cases syringocystadenocarcinoma Most reported SCACP seem to represent examples in situ adenocarcinoma or invasive adenocarcinomas, whereas our knowledge, only 3 were described with squamous cell carcinoma. In present series 2 cases, we report differentiation and 1 case regional lymph node metastasis. The...

Microvascular surgery plays a crucial role in reconnecting micrometer-scale vessel ends. Suturing remains the gold standard technique for small vessels; however, suturing collapsed lumen of microvessels is challenging and time-consuming, with risk misplaced sutures leading to failure. Although multiple solutions have been reported, emphasis has predominantly on resolving challenges related arteries rather than veins, none proven superior. In this study, we introduce an innovative solution...

Abstract The purpose of the present report is to evaluate outcome subacute and delayed period microsurgical reconstructions traumatic extremity defects pediatric patients. Eighteen free tissue transfers had been performed in 18 Patients ranged age from 5 17 years a median 12.05 years. time between trauma flap transfer varied 8 86 days (mean, 30.8 days). Hospital stay 90 days, with mean 38.7 days. Postoperative complications were seen patients (44.4%). Re‐exploration for venous thrombosis was...

Diclofenac sodium (DS) is used primarily to treat fever and alleviate pain inflammation. We investigated the effects of DS exposure during gestation on testes rat pups investigate safety its use prenatal period. Pregnant rats were separated into control, saline, low dose, medium dose high groups. was given between weeks 15 21 gestation. Total numbers spermatogonia Sertoli cells counted in 7-day-old male using physical disector method. By end study, total number decreased significantly a...

Sakai et al described a composite radial forearm plamaris longus flap (CRFPL) for total lower lip reconstruction. However, this technique is not fully capable of preserving satisfactory oral competence, especially when the patients are speaking or eating. Valuable modifications and refinement using forearm-palmaris have been to improve functional outcomes technique. The purpose case report present successful empowered static partial dynamic reconstruction massive defect with CRFPL. A...

Reconstruction after total maxillectomy with preservation of the orbital contents is technically more challenging than when combined exenteration. It results in severe complications if content not supported. We would like to introduce a new technique using free rectus abdominis myocutaneous (RAM) flap anterior sheath support patient who underwent globe-sparing maxillectomy. The large resection recurrent maxillary peripheral nerve tumor was performed 34-year-old male patient. Right RAM...

The unique anatomy of the orbita and different behavior each malignant tumor cause us to perform various types orbital exenteration that yields varying defect which has own specific demands in terms reconstruction. Current classification defects seems not be adequate provide detailed description. This study reviews 50 offer a more effective anatomical system.Over 15 years period, 47 patients were reconstructed. Defects categorized according resected wall, dura, ethmoid resection. If...

Abstract Objective: To demonstrate the clinical and histopathological features of nodular fasciitis in parotid region. Case report: A 24-year-old man presented with a palpable mass superior border gland. The was firm immobile, smooth surface. Fine needle aspiration cytology revealed proliferating fibroblasts, macrophages adipocytes among blood cells. Although superficial parotidectomy initially planned, total excision performed, as observed to be located periphery tissue. Nodular diagnosed,...

Chondrocutaneous (ChC) grafts have been used for nasal alar reconstruction years. One of the consequences using these is restriction in dimensions. In this study, we presented our results which ChC bigger than 20 mm length conjunction with a dermal turnover flap full-thickness subunit defects. Technical details and 8 subunits reconstructions patients were evaluated. Follow-up period ranged from 10 to 27 months, mean 18.3 months. We achieved satisfactory without partial or total graft...

Basal cell carcinoma is exceedingly common, but giant basal carcinomas (GBCCs) are rare. We retrospectively reviewed 34 patients with GBCC on the head and neck region treated aggressive surgical excision reconstruction in a single operative procedure.The large defects were reconstructed 15 free tissue transfers 20 pedicled muscle, musculocutaneous flaps, skin flaps. able to observe 23 for minimum 5 years after surgery. Locoregional recurrence and/or distant metastasis not observed 22...

Reconstruction of a full-thickness cheek defect, especially one associated with large lip and oral commissure remains challenge. After tumor excision, replacement the mucosa is often necessary. The thin, pliable lining. Because skin forearm ideally suited for lining, being pliable, predominantly hairless, radial flap most frequently used soft-tissue this purpose. In addition, vascularity area allows substantial variation in design flap, both relation to its site size. On other hand, might be...

Although early free flap coverage for lower extremity traumatic defects has been recommended by several authors, it is often not practical due to associated patient injuries or logistics. The aim of this study was evaluate the impact subacute and delayed surgical timing on success.A retrospective analysis adult patients who underwent a microsurgical operation between 2007 2012 following trauma performed. were divided into 2 groups according time period injury operation: group (flap performed...

Bilateral traumatic amputation and limb-threatening injury of the lower extremities is more challenging than unilateral amputation. Successful replantation both has been reported previously. However, orthotopic implantations may not be possible when limbs with different levels section degrees damage to surrounding tissues occurs. It was that crossover replanted foot in combination prosthetic limb better 2 artificial limbs. Hence, should considered anatomic as a result bilateral total or...

Abstract The objective of this study was to describe a predictable and easy-to-use model that can create standardized burn wounds. A 450-nm 1000-mW blue beam laser pointer used wounds on the dorsal skin 24 Sprague Dawley rats. Twelve distinct areas were pulsed for 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21, 23 seconds with help punched plastic card template. Three groups 8 animals killed immediately after third day seventh procedure tissue samples taken histological evaluation measurements....

Currently, free flaps and pedicled are the first treatment choices for large heel ulcer reconstruction. However, flap reconstruction of ulcerations cannot be performed in all diabetics especially with concurrent severe peripheral vascular disease because higher failure rate. In recent years, use acellular dermal matrix (ADM) has emerged as an alternative option extremity ulcers.We present 13 diabetic patients a ulceration exposing calcaneus, who were not eligible surgery due to presence only...

Introduction Postradiation sarcomas constitute approximately 0.5% to 5.5% of all sarcomas. They develop locally 3 20 years after the administration radiotherapy (RT). are generally high-grade tumors. Osteosarcomas, fibrosarcomas, malignant fibrous histiocytoma, angiosarcomas, and leiomyosarcomas most frequently observed. It is rare for these tumors originate from free flaps, this patient report one first in literature. Patient A 59-year-old man was operated on because ethmoid sinus cancer...

Telogen effluvium (TE) is a common form of non-scarring alopecia that may manifest as acute or chronic hair shedding. Several studies evaluated possible relationship between various vitamin and mineral deficiencies TE, but it still controversial topic.This study aimed to investigate the status in patients diagnosed with TE evaluate their correlation anagen ratios (AHR) calculated an automated digital phototrichogram (ADCP).Electronic records 973 were retrospectively analyzed. Demographic,...