A5058816491- Substance Abuse Treatment and Outcomes
- Alcohol Consumption and Health Effects
- Behavioral Health and Interventions
- Neurotransmitter Receptor Influence on Behavior
- Neural and Behavioral Psychology Studies
- Gambling Behavior and Treatments
- Memory and Neural Mechanisms
- EEG and Brain-Computer Interfaces
- Decision-Making and Behavioral Economics
- Neural dynamics and brain function
- Cannabis and Cannabinoid Research
Technische Universität Dresden
2018-2020
University Hospital Carl Gustav Carus
2018-2020
Deutsche Forschungsgemeinschaft
2020
Federal Ministry of Education and Research
2020
National Institute on Alcohol Abuse and Alcoholism
2020
Abstract Pavlovian conditioned cues (CSs) can drive instrumental behavior in alcohol‐dependent patients. However, it remains unclear if the influence of CSs might also promote maladaptive decisions that increase risk relapse. We studied 109 abstinent patients and 93 controls who completed a Pavlovian‐to‐instrumental transfer (PIT) paradigm, assessed patients' subsequent relapse status during 1‐year follow‐up. In our PIT task, participants had to collect “good shells” (instrumental approach)...
Background: Neurodevelopmental and alcohol-induced changes in decision-making have been proposed to critically influence impulsive behaviour adolescents. Objective: This study tested the of acute alcohol administration on choice Methods: Fifty-four males aged 18–19 years were a single-blind placebo-controlled cross-over design. During (infusion resulting an arterial blood concentration 80 mg%) placebo condition (saline infusion), participants performed task battery providing estimates delay...
Background: Studies in humans and animals suggest a shift from goal-directed to habitual decision-making addiction. We therefore tested whether acute alcohol administration reduces promotes decision-making, these effects are moderated by self-reported drinking problems. Methods: Fifty-three socially males completed the two-step task randomised crossover design while receiving an intravenous infusion of ethanol (blood level=80 mg%), or placebo. To minimise potential bias long-standing heavy...
Sex, comprising biological and gender-related distinctions, is a known risk factor for alcohol use disorders. Moreover, sensation seeking, impulsivity, aggression have been found to predict binge drinking reflect behavioral disinhibition. We tested effects of these disinhibited traits on binging during intravenous self-administration (ivASA), method that eliminates sex differences in the pharmacokinetics alcohol. Eighty-five German social drinkers (49 men) completed 3 questionnaires...
Research shows that sensitivity to certain alcohol responses conveys risk for problem drinking. This study aimed determine if high-risk adolescent drinkers infuse more and experience greater alcohol-induced stimulation wanting less sedation than low-risk drinkers.
Abstract Alcohol intoxication may affect self‐reports of alcohol use and related constructs, such as impulsivity dependence symptoms. Improved knowledge about potential systematic reporting biases induced by alcohol, e.g. through disinhibition, be relevant for the assessment intoxicated individuals both in clinical routine research. We therefore randomly assigned 54 socially drinking males aged 18 to 19 without lifetime diagnosis DSM‐IV one two experimental arms: either placebo infusion at...