A5036260497- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Respiratory Support and Mechanisms
- Respiratory and Cough-Related Research
- Inhalation and Respiratory Drug Delivery
- Healthcare Policy and Management
- Smoking Behavior and Cessation
- Primary Care and Health Outcomes
- Delphi Technique in Research
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Economics and Policy
- Pharmaceutical industry and healthcare
- Obstructive Sleep Apnea Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pediatric health and respiratory diseases
- Health and Medical Research Impacts
- Sarcoidosis and Beryllium Toxicity Research
- Lung Cancer Diagnosis and Treatment
- Tracheal and airway disorders
- Cystic Fibrosis Research Advances
- Chronic Disease Management Strategies
- School Health and Nursing Education
- Pleural and Pulmonary Diseases
- Heart Rate Variability and Autonomic Control
- Clinical practice guidelines implementation
University of Toronto
2016-2025
Toronto Western Hospital
2016-2025
University Health Network
2014-2024
Institute for Clinical Evaluative Sciences
2010-2021
Health Sciences Centre
2011-2020
Sunnybrook Health Science Centre
2011-2020
Public Health Ontario
2016-2019
Jisc
2008-2018
McGill University
2018
Institute of Health Services and Policy Research
2018
Chronic obstructive pulmonary disease (COPD) is a common and deadly disease. Long-acting inhaled β-agonists anticholinergics, first-line medications for COPD, have been associated with increased risk of cardiovascular outcomes. When choosing between the medications, patients physicians would benefit from knowing which has least risk.To assess association these classes hospitalizations emergency department visits events.We conducted nested case-control analysis retrospective cohort study. We...
BackgroundThe Duke Activity Status Index (DASI) questionnaire might help incorporate self-reported functional capacity into preoperative risk assessment. Nonetheless, prognostically important thresholds in DASI scores remain unclear. We conducted a nested cohort analysis of the Measurement Exercise Tolerance before Surgery (METS) study to characterise association with postoperative death or complications.MethodsThe included 1546 participants (≥40 yr age) at an elevated cardiac who had...
<h3>Importance</h3> Chronic obstructive pulmonary disease (COPD), a manageable respiratory condition, is the third leading cause of death worldwide. Knowing which prescription medications are most effective in improving health outcomes for people with COPD essential to maximizing outcomes. <h3>Objective</h3> To estimate long-term benefits combination long-acting β-agonists (LABAs) and inhaled corticosteroids compared LABAs alone real-world setting. <h3>Design, Setting, Patients</h3>...
Sarcoidosis-related mortality appears to be rising in North America, with increasing rates females and the elderly. We aimed estimate trends sarcoidosis incidence, prevalence Ontario, Canada.We performed a cohort study using health administrative data from Ontario between 1996 2015. International Classification of Diseases Health Insurance Plan codes were used for case detection. Three disease definitions created: 1) sarcoidosis, two or more physician claims within 2 years; 2) chronic five 3...
E-cigarettes have been steadily increasing in popularity, both as cessation methods for smoking and recreational social reasons. This increase vaping may pose cardiovascular respiratory risks. We aimed to assess symptoms youth users of e-cigarettes cigarettes.A retrospective survey design was utilized Canadian aged 16-25 years. Participants were recruited from the Ontario Tobacco Research Unit Youth Young Adult Registration Panel November 2020 March 2021. A total 3082 subjects completed...
Rationale: Inhaled corticosteroids (ICS) are established medications for the management of both asthma and chronic obstructive pulmonary disease (COPD), two common airway diseases. However, there is still uncertainty with respect to their use in some cases, specifically older adults asthma, people concurrent COPD, COPD (given association ICS pneumonia).Objectives: To compare effectiveness safety or features a real-word setting.Methods: In this retrospective longitudinal population cohort...
Background: Chronic obstructive pulmonary disease (COPD), a largely preventable and manageable respiratory condition, affects an estimated 12% to 20% of adults. Long-acting inhaled β-agonists anticholinergics have both been shown improve COPD outcomes are recommended for moderate severe disease; however, little is known about their comparative effectiveness. Objective: To compare survival in older patients with who initially receive long-acting that anticholinergics. Design:...
Background Patients with chronic obstructive pulmonary disease (COPD) are more likely to be readmitted than patients other medical conditions, yet knowledge regarding such readmissions is limited. We aimed determine factors associated readmission within 30 days of a COPD hospitalization or death an emphasis on examining aspects socioeconomic status and specific comorbidities. Methods A population-based cohort study was conducted using health administrative data from Ontario, Canada. All...
Introduction: Malignant Pleural Effusion (MPE) is common in advanced malignancy. Data are needed on health care utilization and costs. Methods: This population-based retrospective cohort study included patients aged ≥18 years with an MPE diagnosed between January 1, 2004 December 31, 2018. We described the incidence prevalence of from to 2018, trends hospital admissions, emergency department (ED) visits, pleural-based procedures. In 2006 2016 we estimated 2-year costs (2018 US dollars)...